Role of Key Salt Bridges in Thermostability of <i>G. thermodenitrificans</i> EstGtA2: Distinctive Patterns within the New Bacterial Lipolytic Enzyme Family XV by David M. Charbonneau (468136)

“…Despite a high tolerance to non-conservative mutations for folding, all the alanine substitutions were destabilizing (decreasing <i>T</i>_<i>m</i> by 5 to 14°C). …”

Image 1_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.jpeg by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Data_Sheet_1_Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism.docx by Sébastien Bontemps-Gallo (2941824)

“…Using specific enzymatic assays, we were able to demonstrate that hyperacetylation of proteins in S phase appeared to play a role in decreasing the enzymatic activity of at least two glycolytic proteins. …”

Data_Sheet_1_Older males whistle better: Age and body size are encoded in the mating calls of a nest-building amphibian (Anura: Leptodactylidae).XLSX by Florina Stănescu (13879760)

“…The dominant frequency (1381.7 ± 16.2 Hz) decreased with arm length (χ² = 5.244, df = 1, p = 0.022) and had an upward modulation (456.4 ± 11.0 Hz) which increased with age (χ² = 4.7012, df = 1, p = 0.030). …”

DataSheet_1_Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.docx by Mengyao Li (2634310)

“…The production of IFN-γ in CD4⁺ T cells was increased, whereas IL-5 and IL-13 in ILC2 were decreased. Importantly, anti-IFN-γ antibody treatment of Ncf1 deficient mice increased eosinophil infiltration and rescued ILC2 activation in the lung. …”

Table_1_Disentangling the responses of dissolved organic carbon and nitrogen concentrations to overlapping drivers in a northeastern United States forested watershed.DOCX by Manya Ruckhaus (14781274)

“…These results are consistent with the increasing trend in stream DOC concentrations and generally decreasing trend in stream DIN we observed in the long-term data. …”

Image 2_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.tif by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Data_Sheet_1_Host Antiviral Response Suppresses Ciliogenesis and Motile Ciliary Functions in the Nasal Epithelium.docx by Qianmin Chen (9422841)

“…Using this model, we observed reduced ciliated cell differentiation compared to goblet cells, reduced protein and mRNA in ciliogenesis-associated markers, and increased mis-assembly and mis-localization of ciliary protein DNAH5 following treatment with 25 μg/ml Poly(I:C) in differentiating hNECs. …”

Image1_Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways.tif by Kubra Karagoz (6670640)

“…Upregulated downstream targets of BATF, EZH2, and IKZF1 are components of TNFA signaling via NFKB, IL2/STAT5 signaling pathways, and IFNG response pathways. …”

Table_4_Altered Lipid Profile Is a Risk Factor for the Poor Progression of COVID-19: From Two Retrospective Cohorts.docx by Hui Jin (38113)

“…</p>Methods<p>In this retrospective cohort study, we consecutively enrolled 430 adult COVID-19 patients from two Chinese hospitals (one each in Chengdu and Wuhan). …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

Table 2_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Image_3_Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism.TIF by Sébastien Bontemps-Gallo (2941824)

“…Using specific enzymatic assays, we were able to demonstrate that hyperacetylation of proteins in S phase appeared to play a role in decreasing the enzymatic activity of at least two glycolytic proteins. …”

Image_1_Disentangling Environmental Effects on the Tree Species Abundance Distribution and Richness in a Subtropical Forest.TIFF by Guang Feng (1281627)

“…We concluded that soil nutrients were more important than topographical factors in regulating species diversity. …”

Functional Testing of an Inhalable Nanoparticle Based Influenza Vaccine Using a Human Precision Cut Lung Slice Technique by Vanessa Neuhaus (309919)

“…In contrast, we found an antigen-specific induction of the T cell proliferation and differentiation cytokine, IL-2, compared to baseline level (152±49 pg/mg vs. 22±5 pg/mg), which could not be seen for the NP alone. …”

<i>AEBP1</i> expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p by Glenn S. Gerhard (259020)

“…Here we sought to investigate the relationship between <i>AEBP1</i> and hepatic fibrosis. …”

Image_2_Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study.PNG by Romain Icick (12490924)

“…In the Norwegian subsample, we also investigated association with lack of medication.…”

Data_Sheet_1_Where to mount the IMU? Validation of joint angle kinematics and sensor selection for activities of daily living.pdf by Lena Uhlenberg (15212035)

“…Analysis of sensor selection showed that after three sensors for the lower limbs and four sensors for the complex shoulder joint, the estimation error decreased only marginally. Global optimum (lowest RMSE) was obtained for five to eight sensors depending on the joint angle across all ADLs. …”

Image_1_Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism.TIF by Sébastien Bontemps-Gallo (2941824)

“…Using specific enzymatic assays, we were able to demonstrate that hyperacetylation of proteins in S phase appeared to play a role in decreasing the enzymatic activity of at least two glycolytic proteins. …”

Table_2_Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism.XLSX by Sébastien Bontemps-Gallo (2941824)

“…Using specific enzymatic assays, we were able to demonstrate that hyperacetylation of proteins in S phase appeared to play a role in decreasing the enzymatic activity of at least two glycolytic proteins. …”