Genetic variance of a trait under stabilizing selection with multi-population demography. by Aaron P Ragsdale (20968248)

“…In Deme 2, <i>V_G</i> decreases due to their population size reduction. …”

Table_3_Genetic associations between ULK3 and epilepsy: a two-sample Mendelian randomization study.xlsx by Baolai Liu (19369291)

“…Bidirectional MR analyses were conducted to explore these relationships. We selected a set of single nucleotide polymorphisms (SNPs) with an association threshold of less than 1 × 10⁻⁵ as instrumental variables for further analysis. …”

Data_Sheet_1_A Secondary Metabolism Pathway Involved in the Production of a Putative Toxin Is Expressed at Early Stage of Monilinia laxa Infection.xlsx by Maria Villarino (5543435)

“…We identified a class of genes highly expressed at 6 hpi and that their expression decreased to almost undetectable levels at 14 to 48 hpi. …”

Role of Operon <em>aao</em> in Antioxidant Defense in <em>Streptococcus oligofermentans</em> by Peng Zhou (116747)

“…Like paraquat, <em>aao_So</em> mutations increased the expression of SOD, and addition of aminoacetone (final concentration, 5 mM) decreased the mutant’s growth by 11%, indicating that the <em>aao_So</em> mutants are under ROS stress. …”

DataSheet_1_Epidemiology of turbot bacterial diseases in China between October 2016 and December 2019.xlsx by Ye Gao (338234)

“…Vibrio anguillarum was isolated in nine cases (5.81%), and Streptococcus parauberis in five cases (3.23%). …”

The Putative C₂H₂ Transcription Factor MtfA Is a Novel Regulator of Secondary Metabolism and Morphogenesis in <i>Aspergillus nidulans</i> by Vellaisamy Ramamoorthy (459033)

“…The presence of VeA is necessary for the biosynthesis of this carcinogenic compound. We identified a revertant mutant able to synthesize ST intermediates in the absence of VeA. …”

Raw data set for Table 3. by Smriti Shrestha (21212910)

“…Notably, one case of Influenza A/H5N1 was reported in 2019. This study shows that the influenza positivity rate decreased substantially after the COVID-19 pandemic began, possibly due to the stringent public health and social measures implemented during the pandemic. …”

Table_4_Genetic associations between ULK3 and epilepsy: a two-sample Mendelian randomization study.xlsx by Baolai Liu (19369291)

“…Bidirectional MR analyses were conducted to explore these relationships. We selected a set of single nucleotide polymorphisms (SNPs) with an association threshold of less than 1 × 10⁻⁵ as instrumental variables for further analysis. …”

A Spontaneous Mutation of the Rat <em>Themis</em> Gene Leads to Impaired Function of Regulatory T Cells Linked to Inflammatory Bowel Disease by Marianne Chabod (187222)

“…In BN^m rats, we found that the T cell lymphopenia originated in the thymus, was intrinsic to CD4 T lymphocytes, and was associated with the development of an inflammatory bowel disease. …”

Table_1_Overexpression of Cinnamoyl-CoA Reductase 2 in Brassica napus Increases Resistance to Sclerotinia sclerotiorum by Affecting Lignin Biosynthesis.DOCX by Dongxiao Liu (583846)

“…We further evaluated the Sclerotinia resistance of BnaC.CCR2.b overexpression lines at the flower-termination stage and found that the disease lesions on the stems of plants in the T₂ and T₃ generations decreased by 12.2–33.7% and 32.5–37.3% compared to non-transgenic control plants, respectively, at 7days post-inoculation (dpi). …”

Table_2_Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic... by Yi-Tung Chen (6743102)

“…We found that TCRα repertoires, TCRβ repertoires, and CDR3 clonotypes were altered in mCRC patients compared with healthy controls. …”

Data_Sheet_1_G721-0282 Exerts Anxiolytic-Like Effects on Chronic Unpredictable Mild Stress in Mice Through Inhibition of Chitinase-3-Like 1-Mediated Neuroinflammation.DOCX by Hyeon Joo Ham (7623410)

“…Chitinase-3-like 1 (CHI3L1) is expressed in several chronic inflammatorily damaged tissues and is well known to play a major role in mediating inflammatory responses. In the present study, we investigated the anxiolytic-like effect of N-Allyl-2-[(6-butyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-5-yl)sulfanyl]acetamide (G721-0282), an inhibitor of CHI3L1, on mice treated with chronic unpredictable mild stress (CUMS), as well as the mechanism of its action. …”

Table_1_Genetic associations between ULK3 and epilepsy: a two-sample Mendelian randomization study.xlsx by Baolai Liu (19369291)

“…Bidirectional MR analyses were conducted to explore these relationships. We selected a set of single nucleotide polymorphisms (SNPs) with an association threshold of less than 1 × 10⁻⁵ as instrumental variables for further analysis. …”

Demographic Effects of Habitat Restoration for the Grey-Crowned Babbler <i>Pomatostomus temporalis</i>, in Victoria, Australia by Peter A. Vesk (770301)

“…Restoration was responsible for a difference of about one bird per group of 3-5 individuals; this is an important effect on the reproductive success of the social group. …”

Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip by Xuanchun Huang (17359851)

“…Reverse Mendelian randomization suggested that the onset of heart failure might potentially influence the levels of four inflammatory factors, with ARTN and FGF5 decreasing after the onset of heart failure, and SLAM and MMP-10 increasing. …”

Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration by Victoria Begley (4670281)

“…RNA pol II profiles at 5ʹ exhibited significant alterations that were compatible with decreased elongation rates in the absence of Xrn1. …”

Data_Sheet_2_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). The functions of DNA transcription, amino acid metabolism (including histidine, lysine, and isoleucine), ATP metabolism, and phospholipid metabolism significantly decreased, while glucose metabolism, protein acetylation, and aspartate kinase activity significantly increased in the OA group. …”

Gene expression and metabolite profiling of gibberellin biosynthesis during induction of somatic embryogenesis in <i>Medicago truncatula</i> Gaertn by Rafał Igielski (4281487)

“…Moreover, by analyzing expression of <i>MtBBM</i>, SE marker gene, we confirmed the inhibitory effect of manipulation in GA_s metabolism, applying exogenous GA₃, which not only impaired the production of somatic embryos, but also significantly decreased expression of this gene.…”

Data_Sheet_3_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). The functions of DNA transcription, amino acid metabolism (including histidine, lysine, and isoleucine), ATP metabolism, and phospholipid metabolism significantly decreased, while glucose metabolism, protein acetylation, and aspartate kinase activity significantly increased in the OA group. …”

Intragenic <i>ERG</i> Deletions Do Not Explain the Biology of <i>ERG</i>-Related Acute Lymphoblastic Leukemia by Eliska Potuckova (525220)

“…They represent the only genetic lesion described so far present in the majority of cases clustering into a subgroup of B-other subtype characterized by a unique gene expression profile, probably sharing a common, however, not yet fully described, biological background. We aimed to elucidate whether <i>ERG</i> deletions could drive the specific biology of this <i>ERG</i>-related leukemia subgroup through expression of aberrant or decreased expression of wild type <i>ERG</i> isoforms. …”