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61481
Gfi1 is required for the generation of LMPPs.
Published 2016“…(K) HSC (Lin<sup>-</sup>Sca1<sup>+</sup>c-Kit<sup>+</sup>Flt3<sup>-</sup>), MPP (Lin<sup>-</sup>Sca1<sup>+</sup>c-Kit<sup>+</sup>Flt3<sup>low</sup>), LMPP (Lin<sup>-</sup>Sca1<sup>+</sup>c-Kit<sup>+</sup>Flt3<sup>+</sup>) and CLP (Lin<sup>-</sup>IL7R<sup>+</sup>Sca1<sup>+</sup>c-Kit<sup>+</sup>) were gated and analyzed for cell death by Annexin V staining. (L) Schematic representation of lymphoid development from Hematopoietic Stem Cells (HSC) to Pro B cells with the different steps including Multipotent Primed Progenitors (MPP), Lymphoid Primed Multipotent Progenitors (LMPP), Common Lymphoid Progenitors (CLP) and Pre-pro B cells. …”