TrkB impacts tumor growth, migration, and invasion in vitro. by Wei Bao (241898)

“…Cells were counted with a microscope in five random high-powered fields. Invasion ability was significantly decreased in HEC-1B^sh−TrkB#1 and HEC-1B^sh−TrkB#3 cells (*<i>p</i><0.05, **<i>p</i><0.01; NS, not significant), and it was enhanced in Ishikawa^TrkB cells (*<i>p</i><0.05; NS, not significant). …”

Supplementary Material for: Risk Factors Assessed in Adolescence and the Later Risk of Stroke in Men: A 33-Year Follow-Up Study by Högström G. (3683686)

Table_1_Use of a Smartphone Application to Speed Up Interhospital Transfer of Acute Ischemic Stroke Patients for Thrombectomy.DOCX by Sheng-Ta Tsai (255653)

“…The total number of transfer patients increased over the years: 63, 113, 175, respectively. The mean door-to-puncture time decreased significantly, going from 109, through 102, to 92 min. …”

Firing rate propagation through networks of gain-scaling and nongain-scaling neurons. by Julijana Gjorgjieva (255641)

“…Bottom: The network mean firing rates for a range of mean input currents (to layer 1) as a function of layer number, with a clear convergence to the fixed point by layer 5. …”

Data from: The efficacy of inactivated vaccine against H5 clade 2.3.4.4b highly pathogenic avian influenza virus in turkeys by Erica Spackman (17362552)

“…There was 100% survival in all groups except the sham exposure group which had 100% mortality. A significant decrease in viral shedding was observed in all exposed groups compared to the shams, although the 9wk group shed significantly higher quantities by the cloacal route at seven days post challenge (DPC) compared to the 3wk group. …”

Economic evaluation of brief cognitive behavioural therapy for social activation in recent-onset psychosis by Ben F. M. Wijnen (4997315)

“…</p><p>Methods</p><p>A health-economic evaluation was conducted alongside a single-blind randomised controlled trial in two parallel groups: guideline congruent treatment as usual (TAU; n = 50) versus TAU augmented with adjunct CBTsa (n = 49). …”

Joule heating of the brain tissue during the application of pulsed electric fields for e-biopsy. by Ilai Genish (12569114)

“…Panels <b>a-c</b> show the simulation for high voltage, short-duration protocol: 40 pulses 1000 V, 40 μs, 4 Hz, coupled with the simulation for low voltage, long-duration protocol: 40 pulses 50 V, 15 ms, delivered at 4 Hz. …”

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent <i>STAG2</i> Mutation by Andrew S. Brohl (596305)

“…We report here the largest genomic survey to date of 101 EFT (65 tumors and 36 cell lines). Using a combination of whole genome sequencing and targeted sequencing approaches, we discover that EFT has a very low mutational burden (0.15 mutations/Mb) but frequent deleterious mutations in the cohesin complex subunit <i>STAG2</i> (21.5% tumors, 44.4% cell lines), homozygous deletion of <i>CDKN2A</i> (13.8% and 50%) and mutations of <i>TP53</i> (6.2% and 71.9%). …”

Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance - Fig 7 by Helen E. McNeil (8190873)

“…Data presented are the mean of three independent biological replicates and are shown as the time taken for the fluorescence to decrease by 50% +/- SE. Data were analysed by one way ANOVA. …”

Mosquito-Disseminated Pyriproxyfen Yields High Breeding-Site Coverage and Boosts Juvenile Mosquito Mortality at the Neighborhood Scale by Fernando Abad-Franch (127663)

“…</p><p>Methodology/Principal Findings</p><p>We conducted a four-month trial within a 20-month study to investigate mosquito-driven dissemination of PPF dust-particles from 100 ‘dissemination stations’ (DSs) deployed in a 7-ha sub-area to surveillance dwellings and sentinel breeding sites (SBSs) distributed over an urban neighborhood of about 50 ha. …”

Data_Sheet_1_Data-Driven Modeling of Global Storm Surges.PDF by M. Tadesse (8762661)

“…For extreme events, the average correlation decreases to 0.54 (0.33) and RMSE increases to 14.5 (13.1) cm for extratropical (tropical) regions. …”

Noise reduction and quantification of fiber orientations in greyscale images by Maximilian Witte (8313381)

“…A comparison to a state-of-the-art band-pass method revealed that the AF method is more suitable for the application on greyscale fiber images, since the error of the fiber dispersion significantly decreased from (33.9 ± 26.5)% to (13.2 ± 12.7)%. Both methods were found to accurately quantify the mean fiber orientation with an error of (1.9 ± 1.5)° and (2.3 ± 2.1)° in case of the AF and the band-pass method, respectively. …”

Impact on functionality of the paliperidone palmitate three-month formulation in patients with a recent diagnosis of schizophrenia: a real-world observational prospective study by Maria Paz Garcia-Portilla (8898926)

“…The total PSP score increased from a mean of 68.5 (15.3) at baseline to a mean of 72.1 (15.4) at month 6 and 74.8 (16.7) at month 12 with a before-and-after difference of 3.6 (95% CI, 1.6 to 5.5, p < 0.001) at month 6 and 6.2 (95% CI, 4.2 to 8.3, p < 0.001) at month 12. …”

<b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b> by Jincy Immanuel (17735170)

“…Women treated early (n=213) showed lower mean glucose (MG) and mean fasting glucose (MFG) compared with those treated late (n=116) (MG:5.7±0.4 vs. 5.9±0.5, p<0.001, MFG:5.2±0.3 vs. 5.3±0.4, p=0.004) with greater optimal glycemia (74.6% vs. 59.5%, p=0.006) and similar glycemic variability. …”

Datasheet1_Beat-to-beat alterations of acoustic intensity and frequency at the maximum power of heart sounds are associated with NT-proBNP levels.docx by Kazuhiro Fujiyoshi (8910803)

“…The cutoff values of ΔS₁ and ΔfS₁ for discriminating the presence of high-risk HF were 4.0 dB and 5.0 Hz, respectively.</p>Conclusions<p>Despite significant attenuations of all four components of HS by BMI, beat-to-beat alterations of both intensity and frequency of S₁ were associated with the severity of HF. …”

Nitrated BLG enhances the anaphylactic response in BLG immunized animals. by Susanne C. Diesner (359191)

“…Animals challenged with BLGn showed a significant decline of body temperature compared to BLG and BLGs, while in OVM allergic mice decrease was most prominent in OVMs. Mean temperatures of all groups at 30 min were compared using One-way ANOVA prior to Tukey multiple comparison test (*P>0.05, **P<0.01, ***P<0.001). …”

Enhanced proliferation inhibition in TKI-resistant cell lines after sitravatinib treatment. by Melissa Dolan (7114667)

“…(G) Corresponding IC50 values from MTS proliferation assays for P or SuR/AxR cell variants following sitravatinib or cabozantinib treatment (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0220101#pone.0220101.s004" target="_blank">S2 Fig</a> for additional MTS proliferation assays). …”

The IgE repertoire is closely related to the IgG1 repertoire. by Adriana Turqueti-Neves (820798)

“…(D) Morisita-Horn indices show the relatedness (0 = unrelated; 1 = identical) between 1,000 randomly selected CDR3 sequences of the IgE and IgG1 repertoires or IgE and IgM repertoires (mean + standard deviation [SD], <i>n</i> = 3). (E) Mean frequency + SD of silent (blue) and nonsilent (red) mutations in V_H segments of IgG1 and IgE. …”

Datasheet1_Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms.pdf by Shirli Tay (13991808)

“…</p>Results<p>35 patients were identified (21 rPEVAR; 14 rEVAR), 86% were male with a mean age of 72 ± 9 years. All patients underwent emergent endovascular aortic repair with 100% technical success. …”

The impact of excessive DNA amounts used for bisulfite conversion on the amplification efficiency and the methylation level of <i>LINE-1</i> and <i>Alu</i>. by Trang Thi Quynh Tran (20485595)

“…(<b>D, E</b>) An increase in methylation level of <i>LINE-1</i> (D) and <i>Alu</i> (E) was associated with a decrease in DNA input for bisulfite conversion. …”