Translocation of HMGB1 into extranuclear and extracellular milieu in LPS/GalN-treatment. by Noriyuki Kuroda (545666)

“…GL-treatment strongly inhibits immunoreactivity of cytoplasmic and additional extracellular HMGB1 (<b>F</b>) and significantly retrieve a decrease of intranuclear immunoreactive products (<b>H</b>). …”

Loss of <i>Tbx4</i> and <i>Tbx5</i> causes reduced lung branching and lethality at birth. by Ripla Arora (145097)

“…H & E on histological sections shows a decrease in lung size at E12.5 in the conditional <i>Tbx4</i> null;<i>Tbx5</i> heterozygous lungs (G,H,). …”

Supplementary Information Files for 'Intraarticular injection of bone marrow-derived mesenchymal stem cells enhances regeneration in knee osteoarthritis' by Emily Claire Doyle (8383038)

“…Likewise, signifcant improvements were reported when using lower (24×106 ) and higher (100×106 ) cell numbers, although adverse efects including persistent pain and swelling were a consequence. …”

Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine by Chordoma Foundation (4391989)

“…A panel of 4 chordoma cell lines were seeded in a white-walled 96-well plate so that at the start of treatment, 36 hours after plating, the confluence was 15%. …”

Strategies against gHAT in the Mandoul focus. by Marina Antillon (4439002)

“…The active screening algorithm specificity under <i>Mean AS & VC (a)</i> is 99.93% and for the strategies <i>Mean AS & VC (b)</i>, <i>Mean AS</i> and <i>Max AS</i> it is 100%. …”

Quantitative structure activity relationship studies of novel hydrazone derivatives as α-amylase inhibitors with index of ideality of correlation by Meenakshi Duhan (4592857)

“…Molecular dynamics simulations performed on protein–ligand complex for 100 ns, the protein gets stabilised after 20 ns and remained below 2 Å for the remaining simulation. …”

Self-limiting of the gTLR9 signaling by <i>gTlr9</i> alternative splicing. by Frank Fang-Yao Lee (2210863)

“…DRB pre-treatment (0 h) led to slight increase of <i>9A</i> (<b>B</b>) and decrease of <i>9B</i> (<b>C</b>) (Cf. the two gray bars vs. white and black bars). …”

Top 16 pfam domains with least selective active drugs. by Tyler William H. Backman (3726991)

“…We also excluded domains with under 100 amino acid residues in the homology model, to avoid small repeats and domains unlikely to be drug targets. …”

Tinnitus development, hearing loss and sleep disruptions assessed over time. by Linus Milinski (10532121)

“…Displayed values correspond to the m(thresh) metric used to calculate the tinnitus index (TI, see panel <b>A</b>) for each individual case. Values are based on gap detection thresholds fitted on a continuous scale ranging from 0–100%. 100% corresponds to a gap detection threshold of 3ms, and the remaining gap lengths (5, 10, 20, 50, 270ms) correspond to the evenly spaced decrements in threshold (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0304306#sec002" target="_blank">methods</a> for details). …”

Changes in first-time registration for opioid agonist treatment in Ireland between 1999 and 2019 by Peter McCarron (58489)

“…</p> <p>The overall incidence of first-time treatments for opioid use decreased from 40.7 per 100,000 in 1999 to 23.0 per 100,000 in 2019 (<i>p</i> < .001). …”

Image_1_Immune Protective Evaluation Elicited by DNA Vaccination With Neospora caninum Dense Granules Proteins in Mice.TIF by Guili Yu (10201136)

“…The immune protective efficacy revealed that pcNcGRA4, pcNcGRA14, and pcNcGRA17 DNA vaccines could individually increase the survival rate to 50, 37.5, and 25% in comparison with 0% in the control group; prolong the survival time more than 20.88 ± 11.12, 18.88 ± 10.83, and 16.63 ± 10.66 days compared with the control group of 4 ± 1.31 days; and decrease parasite burden in the brains to 297.63 ± 83.77, 471.5 ± 110.74, and 592.13 ± 102.2 parasites/100 ng comparing with 1221.36 ± 269.59 parasites/100 ng in the control group. …”

Image1_Passive heating-induced changes in muscle contractile function are not further augmented by prolonged exposure in young males experiencing moderate thermal stress.tif by Viktorija Treigyte (14819209)

“…Under the unfatigued state, HWI did not affect electrically induced torques at 20 Hz (P20) and 100 Hz (P100). However, it induced a shift towards a faster contractile profile during both SP and IPP, as evidenced by a decreased P20/P100 ratio (p < 0.05) and an improved muscle relaxation (i.e., reduced half-relaxation time and increased rate of torque relaxation; p < 0.05). …”

COINOCULATION WITH Bradyrhizobium AND Trichoderma ALLEVIATES THE EFFECTS OF SALT STRESS IN COWPEA by LANESSA VIEIRA DA SILVA (7028990)

“…The stem diameter increased in cowpea coinoculated with Bradyrhizobium and T. asperelloides, mainly in plants subjected to salt stress at 100 mmol L-1 NaCl. Cowpea coinoculated with Bradyrhizobium and T. asperelloides maintained a higher content of free ammonia and organic compounds in its nodules even under salt stress. …”

Effect of initial total solids concentration on volatile fatty acid production from food waste during anaerobic acidification by Quan Wang (31224)

“…Considering the above variables, we conclude that initial TS of 100 g/L shall be the most appropriate to VFAs production.…”

Current responses of different ChR variants to light steps of increasing intensities. by Marion Mutter (490174)

“…<p>In each panel, we show the light responses of a certain variant of ChR to 8 different 1-sec light steps of increasing intensity (top). …”

Data_Sheet_1_Single-Cell Electrical Stimulation Using CMOS-Based High-Density Microelectrode Arrays.docx by Silvia Ronchi (6451451)

“…Stimulation signals as low as 70 mV or 100 nA, with pulse durations as short as 18 μs, yielded measurable action potential initiation and propagation. …”

Table 1_Changes in the provision of psychiatric beds and incarceration in the Eastern Mediterranean Region from 1990 to 2022.docx by Adrian P. Mundt (16963860)

“…The median prevalence of psychiatric beds decreased from 8.8 to 5.8 per 100,000 population (-35%) between 1990 and 2022. …”

Image_1_High-dimensional single-cell analysis unveils distinct immune signatures of peripheral blood in patients with pancreatic ductal adenocarcinoma.pdf by Yu Pan (162493)

“…The proportion of cytotoxic CD8+ T cells and the level of cytotoxicity per cell were increased in PDAC patients, with reduced TCR clonal diversity. We also found a significantly enriched S100A9+ monocyte population and an increased level of TIM-3 expression in immune cells of peripheral blood in PDAC patients. …”

Table_1_Microplastics Effects on Reproduction and Body Length of the Soil-Dwelling Nematode Caenorhabditis elegans.pdf by Lion Schöpfer (8693133)

“…This decline was independent on the plastic type. We detected a tendency toward greater decreases in offspring at higher concentrations. …”

Table_1_High-dimensional single-cell analysis unveils distinct immune signatures of peripheral blood in patients with pancreatic ductal adenocarcinoma.doc by Yu Pan (162493)

“…The proportion of cytotoxic CD8+ T cells and the level of cytotoxicity per cell were increased in PDAC patients, with reduced TCR clonal diversity. We also found a significantly enriched S100A9+ monocyte population and an increased level of TIM-3 expression in immune cells of peripheral blood in PDAC patients. …”