MCH expression is Shh dependent. by Sophie Croizier (337099)

“…The mutant embryo is not viable due to multiple malformations in particular of the head. Scale bar: A = 1,5 mm; B = 4 mm. (C) The relative level of pMCH mRNA was assessed by quantitative real-time PCR in one Shh+/+ and one Shh −/− E13 embryos. pMCH mRNA level was 85% lower in the mutant. …”

Model dynamics with <i>β</i>₁ = 0. by Kiersten Utsey (9553724)

“…The concentrations then rapidly decrease to a level that does not support HBB nucleation. …”

Surgical treatment of macrodactyly of the foot in children by Lu Chen (75170)

Ift88 facilitates polarization in migrating cells. by Christopher Boehlke (74656)

“…<b>(D)</b> Quantification of Golgi apparatus polarization (for details see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140378#sec009" target="_blank">methods</a>) showed a significant decrease of polarized Golgi in Ift88-knockdown conditions (+Tet: 37.5 ±4.8%) compared to non-induced controls (-Tet: 53.6 ±3.3%), p<0.05 (Chi²-Test), n = 3, -Tet: 258 cells/ +Tet: 269 cells. …”

Old mice have increased numbers of circulating and recruited Ly6C^high monocytes during the course of <i>S</i>. <i>pneumoniae</i> colonization. by Alicja Puchta (845752)

“…<i>pneumoniae</i> colonization was measured by a high sensitivity ELISA. The data represent the mean (± SEM) of 3 mice per time point. …”

8oxoG inhibits TRF1 binding to telomeric DNA by Patricia L. Opresko (7493)

“…All rights reserved</p> Boxes indicate the GGG runs of the tandem telomeric repeats, and (X) marks the position of the 8oxoG lesion(s) within the G runs (see ). Substrates (2.5 nM) were incubated alone (−) or together with decreasing concentrations of purified TRF1 (200, 100, 50 or 25 nM) (lanes 2–5, 7–10, and 12–15, 17–20, 22–25 and 27–30) for 20 min at 4°C in TEL buffer. …”

An SMN gradient in the <i>Drosophila</i> adult testis. by Stuart J. Grice (225342)

“…(E–G) SMN is enriched in GSCs and levels decrease as cells differentiate. (H) Schematic showing the gradient in the testis from (i) the most intense to (v) the least intense. …”

Deterministic Model: Robustness Analysis of the Period and Amplitude of the Internal cAMP Oscillations with Respect to Perturbations in the Model Parameters and Initial Conditions by Jongrae Kim (36310)

“…The distributions of the amplitudes also show a similar tendency, i.e., the mean value decreases and the standard deviation increases as the magnitude of the perturbation increases. …”

Supplementary Material for: Early-Life Stress Perturbs Key Cellular Programs in the Developing Mouse Hippocampus by Wei L. (4146940)

Data_Sheet_1_Altered flexor carpi radialis motor axon excitability properties after cerebrovascular stroke.PDF by C.S. Klein (15783482)

“…A decrease (14%) in Na⁺ channel inactivation rate (Aah) was also needed to fit the paretic axon recovery cycle. …”

Effect of LFS on currents and gene expression of GABAergic receptors. by Samireh Ghafouri (7832474)

“…Control: n = 8, Control+LFS: n = 5, Kindled: n = 5, Kindled+LFS: n = 5. Data are shown as mean±SEM. * p<0.05, ** p<0.01 and *** p<0.001 compared to the control group.…”

Dynamic correlation between the rate of HIV-1 evolution and the rate of CD4+ T cell count decline. by Ha Youn Lee (375454)

“…<p>(A) Evolutionary rate and CD4+ T-cell level as a function of time relative to seroconversion. …”

JS model produces sustained arch-shaped gamma oscillations within the previously identified superlinear inhibitory regime. by R Krishnakumaran (12085900)

“…Input combinations used in (C) were chosen to have constant I_E (5 vertically distributed markers; the increase in size modelled as an increase in I_I) while those used in (D) simultaneously varied in I_E and I_I (5 markers distributed obliquely; the increase in contrast modelled as a linear increase in I_E and I_I). …”

Effects of Sacubitril/Valsartan on clinical symptoms, echocardiographic parameters, and outcomes in HFrEF and HFmrEF patients with coronary heart disease and chronic kidney disease by Dominick Mkombozi Raphael (10435309)

“…A reduction of 15.6% was observed in HFrEF patients, whereas a reduction of 7.1% was observed in HFmrEF patients. …”

No Evidence for Ionotropic Pheromone Transduction in the Hawkmoth <i>Manduca sexta</i> - Fig 8 by Andreas Nolte (409768)

“…</b> Only HMA decreased LLPR during rest (B,D). The LLPR neither includes the phasic, nor the tonic pheromone response (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166060#pone.0166060.g002" target="_blank">Fig 2C</a>), but was measured from 5–300 s after pheromone stimulation. …”

Hypothermia suppressed MNU-mediated DNA demage by TGF-β1 unregulation and TNF-α down-regulation. by Gangjun Du (450828)

“…<p>A and B. Hypothermia decreased MNU-induced BEAS-2B cell DNA demage examined by comet assay. …”

Integrated NMR interface and mutagenesis data illustrated onto the HPV16 E6 3D structure. by Katia Zanier (17371)

“…Side-chains that when mutated decrease E6/pep11** binding in mammalian two-hybrid assays by 1.5-fold or more (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0112514#pone-0112514-g005" target="_blank">Figure 5C</a>) are displayed.…”

Interference from the vertical variation of soil phosphorus and from water stress on growth in maize, the soybean and sunflower by Clovis Orlando Da Ros (8184435)

“…The design was completely randomised with five replications, in a 3 x 2 factorial scheme: three soil depth gradients of P (decreasing, increasing and nil) and two conditions of soil water availability (with and with no water stress). …”

EIT images for all algorithms from three representative animals. by Bartłomiej Grychtol (613117)

“…Each column shows images for a different algorithm. Peep, positive end-expiratory pressure; ZEEP, zero end-expiratory pressure; V_T tidal volume.…”

Effect of glibenclamide on the [Ca²⁺]_i transient elevation induced by extracellular ATP. by Duo-ling Li (523730)

“…<p>A, C, time series of the mean F ratio during the application of different agents. …”