The novel <i>carboxylesterase 1</i> variant c.662A>G may decrease the bioactivation of oseltamivir in humans by Jaeseong Oh (3947381)

“…A novel <i>CES1</i> c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an <i>in silico</i> analysis. …”

L665W decreased AR5A binding to H77/JFH1 particles and to the E1/E2 complex in H77/JFH1 infected cells, but did not alter receptor dependency. by Rodrigo Velázquez-Moctezuma (3776023)

A decrease in circulating CXCR5+CD4+ Tfh cells is associated with HCC progression, and CXCR5+CD4+ Tfh cells are decreased in tumor regions. by Yiqiong Jia (692871)

“…<p>(A) The prevalence of CXCR5+CD4+ Tfh cells decreases with progressive stages in HCC. …”

Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function). by Luciana Kase Tanno (785410)

“…<p>Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function).…”

Sildenafil decreases intestinal transit time in a DSS-recovery model of IBS. by Sarah K. Sharman (3966476)

Irbesartan Decreases ¹⁴C-FDG and ^99mTc-annexin A5 Accumulation Levels. by Yan Zhao (58882)

Subjects:

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)

Decreased Sho levels in ScN2a-Sho cells. by Joel C. Watts (195735)

“…(<b>C</b>) Quantification of Sho levels in ScN2a-Sho-1 (<i>n</i> = 10) and ScN2a-Sho-2 (<i>n</i> = 5) subclones revealed a significant decrease of 40–45% compared to the uninfected parental cell line (<i>n</i> = 15) (***<i>P</i><0.001).…”

CpG/c stimulated CLL B cells exhibit decreased survival and decreased activation of the Wnt pathway. by Albert Gutierrez Jr. (342562)

Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs. by Jingping Ge (636557)

“…The nuclear p-SMAD2 decreased in <i>RPL5</i> mutant and corrected lines. …”

Activin A decreases MPTP and LPS-induced inflammation. by Sandy Stayte (728461)

“…<p>Stereological quantification of the left SNpc demonstrated activin A significantly decreased the number of GFAP-immunoreactive cells (A) and Iba1-immunoreactive cells (B) in the SNpc following MPTP. …”

KDM6A mRNA expression is decreased in PTFE mice. by Simon Lebek (9756148)

Inhibition of PKC or Rho protein kinase decreases Ad5 wild type replication <i>in vitro</i>. by Alice Liu (4814415)

Spleen PAX5 significantly decreased in APRIL/BLyS blockade treated mice. by Natalie M. Bath (6316517)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

Interferon-β release is strongly decreased after MNV-S99 infection. by Sandra Niendorf (2832785)

Comparison of mean differences in temperature decreases. by Hans-Jörg Gillmann (8460585)

Subjects:

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…Statistical analysis was performed using ANOVA (F_3.9 = 5.066, **p<0.01; *p<0.05). (<b>C</b>) PC12 cells transfected with MK-STYX, scrambled shRNA, or MK-STYX shRNA-A. 24 hr post-transfection cells were stimulated with NGF or not, and were lysed 24 hr thereafter and immunoblotted. …”

The decreasing rates of V_p with temperature. by Nazlı Tunar Özcan (14833635)

“…In this study, P-wave velocity (V_p), Brazilian tensile strength (σ_t), uniaxial compression strength (σ_c) of Çankırı rock salt were investigated under different temperatures ranging from 20°C to 250°C since the temperature is a factor that causes changes in some physical and geo-mechanical properties of rocks. …”