Region D is transactivated by ETS and GATA factors. by Alexandra Le Bras (243728)

“…The −252/+38 promoter region responds to Ets-1, Erg and Fli-1 and mutation of EBS5 abolished the response to the ETS factors. Mutation of either EBS3 or of EBS4 had no effect on the response to Ets-1 or to Fli-1, however, mutation of EBS3 increased the response to Erg, that of EBS4 decreased it, *** p<0.001, ** p<0.01, * p<0.05.…”

CD20-TCB induces resident T cell proliferation and recruitment of peripheral blood T cells. by Floriana Cremasco (5580266)

“…<p>a-c) Top: Representative histological staining of WSU DLCL2 tumors 24h post second treatment (0.5 mg/kg CD20-TCB or suitable vehicle i.v.). …”

Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells by Tissa T. Manavalan (406097)

“…Knockdown of ZEB1 in LY2 cells recapitulated the effect of miR-200b and miR-200c overexpression resulting in inhibition of LY2 cell proliferation by TAM and fulvestrant, but not the aromatase inhibitor exemestane. Demethylating agent 5-aza-2′-deoxycytidine (5-aza-dC) in combination with histone deacetylase inhibitor trichostatin A (TSA) increased miR-200b and miR-200c in LY2 cells. …”

Phosphinimino-amino Magnesium Complexes: Synthesis and Catalysis of Heteroselective ROP of <i>rac</i>-Lactide by Hongyan Xie (264700)

“…Complexes <b>1</b>–<b>8</b> are phosphinimino-amine-ligated THF-solvated mono­(alkyl)­s, among which <b>1</b>–<b>4</b> adopt twisted tetrahedral geometries, whereas <b>5</b> contains a trigonal bipyramido geometry core. …”

RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors by Hortensia Sanchez-Calderon (186893)

“…By contrast, there was an increase in the nuclear accumulation of FoxM1 and a corresponding decrease in the nuclear cyclin-dependent kinase inhibitor p27^Kip1.…”

Nature of the Entire Range of Rare Earth Metal-Based Cationic Catalysts for Highly Active and Syndioselective Styrene Polymerization by Fei Lin (156666)

“…The activity increased with the decrease in the rare earth metal size, in striking contrast to the literature that has shown that a large metal facilitates a high activity, which was also not a result of an enthalpic effect (Δ<i>H</i>^⧧) or an entropic effect (Δ<i>S</i>^⧧) according to Eyring plots. …”

FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation by Zhanchao Wang (779221)

“…<i>L. paracasei S16</i> affects miR-31a-5p and SATB2 expression. Dual luciferase reporter gene assay confirmed that miR-31a-5p bound to SATB2. …”

Co-immunoprecipitation experiments to examine the interactions of beclin-1 with Bcl-2 and Bcl-xL. by Tai-Ho Hung (306051)

“…Data are presented as mean ± SEM for 5 separate experiments. *, <i>P</i><0.05, in comparison to vehicle controls.…”

TSPO ligand PK11195 treatment alters mouse WAT metabolic gene expression. by Misty M. Thompson (486672)

“…<p>Intraperitoneal administration of PK11195 (5 mg/kg) in 8–10 week-old male C57BL/6 mice significantly decreased the expression of <i>pck1</i> (A) and <i>srebf1</i> (B) genes in WAT and significantly increased the <i>lipe</i> gene expression (C) as compared to vehicle-treated controls. …”

Change in the number of attractors during the learning process. by Tomoki Kurikawa (228085)

“…In the early stages of the learning process, the number of fixed-point attractors increases, while in the later stage (after 5 or 6 learning steps), the number of fixed-point attractors decreases (fixed-point attractors are replaced by limit-cycle attractors).…”

Table_1_Association of thyroid function, within the euthyroid range, with cardiovascular risk: The EPIPorto study.docx by João Sérgio Neves (5772401)

“…On one hand, individuals with higher BMI, larger waist circumference and higher hs-CRP had higher levels of FT3 and FT3/FT4 ratio. On the other hand, a decreased conversion of T4 to T3 (lower FT3, lower FT3/FT4 ratio and/or higher FT4) was associated with a higher prevalence of diabetes, a more adverse lipid profile, a lower eGFR and an increased 10-year risk of cardiovascular events.…”

DataSheet_1_Influence of beam pruning techniques on LET and RBE in proton arc therapy.docx by Helge Henjum (16931607)

“…The LET was increasingly higher within the PTV for each pruning iteration, where the mean LET from the P6-PAT plan was 1.5 keV/μm higher than for the PAT plan, while the P4- and P5-PAT plans provided an increase of 0.4 and 0.7 keV/μm, respectively. …”

Oxygen Consumption Rates (OCR) and respiration parameters in Aur treated N27 cells. by Pamela Lopert (114596)

“…(e) Proton Leak was increased in cells treated with PQ alone or combined with Aur. α = p<0.05 compared to control, β = p<0.05 compared to 100 nM Aur, χ = p<0.05 compared to 300 nM Aur, φ = p<0.05 compared to 100 µM PQ (n = 5−15) as determined by 1-way ANOVA. Bars represent mean ± SEM.…”

Bioenergetic analysis of Opa1 morphants. by Jennifer J. Rahn (343062)

“…<p>Oxygen consumption rates (OCR) were measured in 24, 48, and 72 hpf morphants (mean +/− SEM, n = 5–10). <b>A.</b> Opa1 morphant basal respiration was significantly decreased compared to MMC morphants at 24 and 72 hpf (p = 0.004 (a) and p = 0.0007 (b), respectively). …”

Diversity of insects found in the Woodlot and Grasslands of the Danby Woods at York University by Muhammad Akram (795962)

An AICD-based functional screen to identify APP metabolism regulators-6 by Can Zhang (56016)

“…(B) SY5Y-APP-Gal4 cells stably expressing Ubiquilin 1 specific shRNA (#2) have decreased Ubiquilin 1, mature and immature APP-Gal4, C83-Gal4, AICD-Gal4, and sAPPα levels compared to cells expressing control shRNA. …”

Image_1_Tremor supression following treatment with MRgFUS: skull density ratio consistency and degree of posterior dentatorubrothalamic tract lesioning predicts long-term clinical... by Kain Kyle (15350116)

“…Combined pre-treatment CRST (mean: 60.7 ± 17.3) and HTS (mean: 19.2 ± 5.7) improved by an average of 45.5 and 62.6%, respectively. …”

Image_1_Tremor suppression following treatment with MRgFUS: skull density ratio consistency and degree of posterior dentatorubrothalamic tract lesioning predicts long-term clinical... by Kain Kyle (15350116)

“…Combined pre-treatment CRST (mean: 60.7 ± 17.3) and HTS (mean: 19.2 ± 5.7) improved by an average of 45.5 and 62.6%, respectively. …”

Effect of HPC silencing on phase-locking of PFC neurons to local theta. by Susanne S. Babl (21169261)

“…The theta frequency range (4–12 Hz) is indicated with a shaded rectangle. Lines show mean ± s.e.m. across sessions. …”

Image1_Dynamics of optical properties of sequentially diluted lucigenin aqueous solutions according to luminescence data.TIF by Dmitrii L. Tytik (19855203)