Diarrhea-free days up to day 10. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Gastrointestinal symptoms-free days up to day 10. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Nausea-free days up to day 10. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Flow of patients in Halos trial. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Cough-free days up to day 10. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Dyspnea-free days up to day 10. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Simulations on the response of protein denaturation temperature to changes in environmental temperatures under conditions of threshold selection for kinetic stability. by M. Luisa Romero-Romero (347004)

“…<p>The simulation starts with the final state of the T_ENV = 37°C and τ* = 10⁴ min of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0156657#pone.0156657.g005" target="_blank">Fig 5</a>. …”

<b>Simulated climate change impacts health, growth, photosynthesis and reproduction of high-elevation epiphytic lichens</b> by Fiona Ruth WORTHY (19668100)

Integrated analysis of methylation and gene expression. by Marsha Reyngold (607573)

“…<p><b>A</b>. 80-gene expression signature separates primary breast cancers from regional metastasis. …”

HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling Pathway by Chi-Ting Chiu (734340)

“…Time-lapse experiments with immunoprecipitation further displayed that the association between EB-1 and β-tubulin was significantly decreased following a short-term treatment (2 h), but gradually increased in a prolonged treatment (6-24 h) with HYS-32. …”

Data Sheet 1_Spatiotemporal variability of turbulent fluxes in snow-covered mountain terrain.csv by Rainette Engbers (22611641)

“…Our findings indicate that while higher-resolution simulations improve agreement between measured and modeled variables, they tend to underestimate wind speeds (with a bias of up to 1.5 ± 0.2 m s−1), and turbulent fluxes (up to 14 ± 3.7 W m−2) and consequently lower snow surface temperatures (up to 3.3 ± 0.3 °C). …”

DataSheet1_Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis.docx by Mohammed Y. Behairy (12194234)

“…As a consequence, all other 14 mutations were expected to increase the risk of carcinogenesis, with 5 mutations (G13R, G13C, G13V, P34R, and V152F) expected to have the highest risk. …”

Table_1_The Effect of Kyolic Aged Garlic Extract on Gut Microbiota, Inflammation, and Cardiovascular Markers in Hypertensives: The GarGIC Trial.pdf by Karin Ried (816690)

“…High blood pressure has been linked to gut dysbiosis, with a significant decrease in microbial richness and diversity in hypertensives compared to normotensives. …”

An amine oxidase gene from mud crab, <i>Scylla paramamosain</i>, regulates the neurotransmitters serotonin and dopamine <i>in vitro</i> by Junguo Liu (126628)

“…The expression of <i>SpAMO</i> tended to decrease and then increase in the brain and haemolymph after treatment with 5 mg/kg/d quercetin; after treatment with 50 mg/kg/d quercetin, the expression of <i>SpAMO</i> declined rapidly and remained low in the brain and haemolymph. …”

HIF-dependent effects on carbohydrate catabolism. by Yan Li (23143)

“…Although sima animals showed a similar trend, the decrease observed was not significant. …”

Temperature dramatically modulates the expression of the pigmentation gene <i>tan</i> in posterior abdominal epidermes of females. by Jean-Michel Gibert (68707)

“…(B) Quantification of pigmentation gene expression in posterior abdomen epidermes (segments A5, A6 and A7) from female <i>w</i>^<i>1118</i> pharates (left) and young <i>w</i>^<i>1118</i> adult females (right) grown at 18°C or 29°C (pools of 50 epidermes for pharates and 30 epidermes for adults, n = 3, error bars: standard deviations; gene expression at 18°C has been normalized on gene expression at 29°C). …”

Smallness of spines was important for short-term PKA activity and its time window. by Hidetoshi Urakubo (578508)

“…The membrane AC1 activity rapidly increases cytosolic cAMP level (the number density of black points), which is rapidly decreased by the membrane PDE. In the somas, cAMP level is increased by the membrane AC5, and slowly decreased by the membrane PDE (bottom). …”

Spiropyran Sulfonates for Photo- and pH-Responsive Air–Water Interfaces and Aqueous Foam by Marco Schnurbus (5219201)

“…In fact, SFG spectroscopy shows that with increasing pH the intensity of the O–H stretching band from interfacial water molecules increases, which we associate to an increase in surface net charge. At a pH of 5.3, irradiation with blue light leads to a reversible decrease of O–H intensities, whereas the C–H intensities were unchanged compared to the corresponding intensities under dark conditions. …”

Image_1_EPC infusion ameliorates acute graft-versus-host disease-related endothelial injury after allogeneic bone marrow transplantation.jpg by Weiwei Wang (105069)

“…Interestingly, infusion of EPC reduced the clinical and pathological score of aGVHD, decreased infiltration of mononuclear cells, improved survival as well as upregulated VE-cadherin and downregulated MHC-II molecule.…”

Data_Sheet_1_Double-Sine-Wave Quadri-Pulse Theta Burst Stimulation of Precentral Motor Hand Representation Induces Bidirectional Changes in Corticomotor Excitability.docx by Nikolai H. Jung (3560903)

“…There, a quadruple burst consisted of four single-sine-wave (SSW) pulses with a duration of 160 μs and inter-pulse intervals of 1.5 ms to match I-wave periodicity (666 Hz). …”