Data Sheet 1_Propionic acid supplementation promotes the expansion of regulatory T cells in patients with end-stage renal disease but not in renal transplant patients.pdf by Moritz Anft (11995520)

“…Our data suggest that dietary supplements containing propionate might have a beneficial effect decreasing systemic inflammation in dialysis patients through Treg expansion. …”

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome by Sumedha S. Gunewardena (817801)

“…The average expression of growth factors peak between Day-3 and Day-10, and decrease thereafter. We identified critical biological functions, upstream regulators, and putative transcription modules that seem to govern age-specific gene expression. …”

Impacts of <i>Metarhizium brunneum</i> F52 infection on the flight performance of Asian longhorned beetles, <i>Anoplophora glabripennis</i> by Eric H. Clifton (7354049)

“…The maximum observation for total flight distance was a healthy male that flew 10.9 km in 24 hours on a flight mill. …”

Data Sheet 1_Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.pdf by Robert M. N. Tran (20539130)

“…Heart rate variability analysis showed that SGB with lidocaine on the right or left side caused a decrease in the ratio of the power of low-frequency over high-frequency. …”

Image_1_Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis.tiff by Joseph Kuo (244331)

“…Here, we investigated whether NV556, a cyclophilin inhibitor derived from sanglifehrins, would decrease the development of NASH and HCC in a preclinical mouse model. …”

CXCR4 homodimerization vs. CXCR4 heterodimerization. by Elisabeth Steel (545397)

“…(n = 8, mean ± S.E.) When homogeneity of variance was not met, a Kruskal Wallis test was performed according to the method described by Zar <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093646#pone.0093646-Vischer1" target="_blank">[6]</a>, in which a significant effect of receptor pair on biotinylation signal was found (Hc = 19.84) considered for the critical value X²(2) = 14.067 (p<0.05, ν = 7). …”

Avoided recurrences and costs with adjuvant atezolizumab for patients with early non-small cell lung cancer in Europe by Alastair Greystoke (9562178)

“…Immunotherapies such as atezolizumab may delay or prevent recurrence if given after surgery (known as “adjuvant” treatment) to appropriate patients, but the benefits for all suitable patients remain unclear. We developed a mathematical model based on clinical trials and real-world data that estimated ~5000 recurrences avoided over a 10-year period when adjuvant atezolizumab was available for eligible patients in 5 European countries. …”

Pharmacological blockade of K_ATP channels negates the hippocampal synaptic and neuronal protection afforded by ketones. by Do Young Kim (131974)

“…Asterisks denote significant differences between experimental groups and the control at a specific time-point (*** <i>p</i> < 0.001). The dotted line indicates the mean PS amplitude of the control group. …”

Dose-dependent Inhibition of SNAT4 Transport Activity by DTT and TCEP. by Rugmani Padmanabhan Iyer (381482)

“…<p>Xenopus oocytes expressing wild type SNAT4 were preincubated with DTT (0–10 mM) (A) or TCEP (0–10 mM) (B) for 30 min. [³H] L-alanine uptake assay was then performed in the presence of DTT or TCEP. …”

Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss by Leanne M. Redman (170737)

“…</p><h3>Conclusions</h3><p>For the first time we show that in free-living conditions, CR results in a metabolic adaptation and a behavioral adaptation with decreased physical activity levels. …”

SAP inhibits HMWHA-induced fibrocyte differentiation and potentiates LMWHA-induced fibrocyte inhibition. by Anu S. Maharjan (342245)

“…After 5 days, the cells were air dried, fixed, stained, and the number of fibrocytes was counted. The results are mean ± SEM of fibrocytes per 2.5×10⁵ PBMC (n = 5 separate experiments, except n = 11 separate experiments for HMWHA with no SAP). …”

Effects on increment and decrement bars are consistent with effects on gratings. by Markku Kilpeläinen (356137)

Comparison of average virus neutralization in adapted plaque reduction neutralization tests using liver homogenates of YFV-, MAYV-, and CHIKV-infected mice. by Thaís Alkifeles Costa (16024584)

“…Pairwise analyses indicated differences between all serial dilutions, with the decrease of average neutralization values with increasing dilutions (p< 1.0−6, A and B). …”

Neural Networks To Analyze Market Demographic Data by OS BH-Labs (281477)

“…s Facebook page likes from 10k to almost 18k likes. </p> <p>From the graph presented in the updated pdf, you can clearly see the impact our training phase had on the advertising performance, showcasing how the software package's suggestions increased/decreased page engagement. …”

Seizure changes during study phases. by Mark Bodner (33604)

“…Posterior density was obtained using Markov Chain Monte Carlo methods and implemented using the rjags package <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045303#pone.0045303-Plummer1" target="_blank">[45]</a> within the R computing environment <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045303#pone.0045303-R1" target="_blank">[46]</a>. …”

Effects of the activation and inhibition of NOTCH signalling on spinal cord progenitor cell proliferation and neuronal generation. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm at the level of the 12^th and 13^th somites of an HH13 embryo that was electroporated with NICD at stage HH10. …”

Investigation of the radiosensitization effect of DNA polymerase theta inhibition in homologous recombination proficient and deficient human breast cancer and fibrosarcoma cells by Natalie West (16549035)

“…While the dose required to reach 10% cell survival was unchanged in the wild type cells, the dose decreased by 2 Gy for the HR-deficient cells treated with the Polθ inhibitor. …”

Investigation of the radiosensitization effect of DNA polymerase theta inhibition in homologous recombination proficient and deficient human breast cancer and fibrosarcoma cells by Natalie West (16549035)

“…While the dose required to reach 10% cell survival was unchanged in the wild type cells, the dose decreased by 2 Gy for the HR-deficient cells treated with the Polθ inhibitor. …”

Graphene with high electrical conductivity by Junjie Chen (13997541)

“…If two atoms of some element are brought close enough together so that they interact, the two-atom system has two closely spaced levels for each level of the single atom. If 10 atoms interact, the 10-atom system will have a cluster of 10 levels corresponding to each single level of an individual atom. …”