Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder by Elena Amendola (565348)

“…Here we describe the physiological, molecular, and behavioral phenotyping of a <i>Cdkl5</i> conditional knockout mouse model of CDKL5 disorder. …”

Table_5_PRMT5 Interacting Partners and Substrates in Oligodendrocyte Lineage Cells.DOCX by David K. Dansu (12252515)

“…This analysis identified a similar number of peptides in the two subcellular fractions and a total number of 57 proteins with statistically decreased symmetric methylation of arginine residues in the CRISPR-PRMT5 knockdown compared to control. …”

Source data for Figs 2E, 3A, 4A and 5B. by Isabel Raposo (21615517)

“…To date, it remains unclear whether periodic and aperiodic temporal structure reflect distinct neural mechanisms. Here, we combined computational simulations with a multimodal approach encompassing five experiments, and three different variants of classic spatial attention paradigms, to differentiate aperiodic from oscillatory-based sampling. …”

<i>TBX5</i> R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway by Nariaki Miyao (8655054)

“…We identified a <i>TBX5</i> variant (c.791G>A, p.Arg264Lys), that is over-represented in cardiomyopathy patients. …”

Video_5_Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder.avi by Valerio Laghi (12228728)

“…Bath exposure, as well as microinjection in the coelom, pericardium, brain ventricle, or bloodstream, resulted in a rapid decrease of SARS-CoV-2 RNA in wild-type larvae. …”

table5_Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.pdf by Jordi Rodon (201558)

“…Here, we have screened existing drugs approved for human use in a variety of diseases, to compare how they counteract SARS-CoV-2-induced cytopathic effect and viral replication in vitro. …”

TCR-induced proximal signaling is decreased in <i>Gimap5</i> deficient T cells. by Xi-Lin Chen (803969)

ST2-104 decreases the Aβ_25-35-mediated increase in intracellular Ca²⁺. by Yingshi Ji (9013004)

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)

Dimensional and Coordination Number Reductions in a Large Family of Lanthanide Tellurite Sulfates by Jian Lin (323268)

“…We attribute the transitions to a decrease in the ionic radii of the 4f ions. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Experimental and <i>ab Initio</i> Study of Catena(bis(μ₂‑iodo)-6-methylquinoline-copper(I)) under Pressure: Synthesis, Crystal Structure, Electronic, and Luminescence Pr... by Amagoia Aguirrechu-Comerón (2882069)

“…In particular, the band gap decreases slowly with pressure in a quadratic way with d<i>E</i>_<i>g</i>/d<i>P</i> = −0.011 eV/GPa and d²<i>E</i>_<i>g</i>/d<i>P</i>² = 0.001 eV/GPa².…”

PI+ CD3+ T cells decrease at day 14 after IR while PI+ CD3- cells decrease at all time points. by Jordan A. Gunning (18143970)

Table_1_Elevated hypertriglyceridemia and decreased gallstones in the etiological composition ratio of acute pancreatitis as affected by seasons and festivals: A two-center real-wo... by Wenhua He (5721077)

“…The composition ratio of gallstone AP in the south center was higher than that in the north center (59.5% vs. 49%), especially in summer (62.9% vs. 44.0%) and autumn (61.5% vs. 45.7%, all P<0.001).…”

5-Aza-2’-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats by Xiaomeng Qiao (3139755)

“…Alcohol-drinking behavior and the anxiety related behavior were evaluated by two-bottle choice and open field test. We found that 5-Aza-dc injection into the mPFC significantly decreased alcohol consumption and alcohol preference in alcohol-exposure rats, corresponding to the reduced blood alcohol levels. …”

Mutations in inverted DNA repeats in P_<i>ganS</i> decrease GanR binding. by Cameron Habib (4112590)

Nonstructural 5A Protein of Hepatitis C Virus Interacts with Pyruvate Carboxylase and Modulates Viral Propagation by Seung-Ae Yim (430539)

“…By employing tandem affinity purification method, we identified pyruvate carboxylase (PC) as a cellular partner for NS5A protein. …”

The aquaporin 5 -1364A/C promoter polymorphism impacts on resolution of acute kidney injury in pneumonia evoked ARDS by Tim Rahmel (5244230)

“…Accordingly, we tested the hypothesis that the <i>AQP5</i> promoter -1364A/C polymorphism is associated with AKI in patients suffering from pneumonia evoked ARDS.…”

Heat-treated spores show a decrease in the overall number of spores that are able to germinate and grow out within 5 hours. by Rachna Pandey (394151)