Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease by Sandra L. Dabora (206838)

“…Kidney angiomyolipomas regrew when sirolimus was discontinued but responses tended to persist if treatment was continued after week 52. We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). …”

Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

“…The pre-defined secondary outcomes were better in the Tac group compared to the control group. The frequency of decrease in pcUACR and percentage change of UPCR (pcUPCR) ≥50% at 16 weeks were 65.0% (13/20) and 55.0% (11/20)in the Tac group, and 25.0% (5/20) and 15.0% (3/20), in the control group, respectively (p = 0.025 for pcUACR and p = 0.019 for pcUPCR). …”

SARS-CoV‑2 Delta Variant Decreases Nanobody Binding and ACE2 Blocking Effectivity by Mert Golcuk (10789806)

SARS-CoV‑2 Delta Variant Decreases Nanobody Binding and ACE2 Blocking Effectivity by Mert Golcuk (10789806)

CK2α decreases CLK transcription factor activity. by Áron Szabó (450885)

Overexpression of Pax6 decreases Olig2 protein levels. by Eun Sook Jang (217069)

“…(<b>a</b>) Oli-Neu cells were transfected with flag-tagged WT Pax6 (WT), Pax6(5a)R128C (128), or eGFP control vector (-). …”

Mean Decrease in Margin (MDM) variable importance. by Yuliya V. Karpievitch (259460)

At E9.5 Actb^−/− neural crest cells show a significant decrease of cadherin-11 expression. by Davina Tondeleir (426905)

“…We only observed a significant reduction of cadherin-11 intensities in Actb^−/− neural crest cells at E9.5. …”

HC-070 decreases anxiety in a standard EPM. by Stefan Just (4811358)

Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study by Sérgio Aparecido Cleto (3143949)

“…Direct bilirubin and the arterial oxygen tension/fraction of inspired oxygen ratio were significantly higher in the SLED group. We identified the following risk factors (sensitivities/specificities) for mortality in severe leptospirosis: age ≥ 55 years (67%/91%); serum urea ≥ 204 mg/dl (100%/70%); creatinine ≥ 5.2 mg/dl (100%/58%); Acute Physiology and Chronic Health Evaluation II score ≥ 39.5 (67%/88%); Sequential Organ Failure Assessment score ≥ 20.5 (67%/85%); and inspiratory pressure ≥ 31 mmHg (84%/85%).…”

Detection of epistasis is confined in a time window whose width is controlled by the mean selection coefficient. by Gabriele Pedruzzi (5753792)

Propagation of an action potential through ephaptic coupling is achieved for a decreased extracellular conductivity. by Karoline Horgmo Jæger (6785450)

Effect of iron mining tailings as a red ceramic additive for decreased sintering temperature by Igor Brumano Coelho Amaral (10472061)

“…We produced test pieces including a mixture of soil with 10 and 20% content of waste exposed to the sintering process at temperatures of 750, 850 and 950° C. …”

Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf by Lisa J. M. Slimmen (16464600)

“…Percentage of AMs expressing lipid scavenger CD36 was low overall (mean 20.1% ± 16.5) and did not correlate with other factors. …”

siRNA-mediated APP-BP1 knock-down significantly decreases BrdU-incorporated fetal neural stem cells. by Yuyoung Joo (236048)

<i>SIRT6</i> Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort by Mindi J. TenNapel (679433)

Panel (a) shows ensemble mean global mean near-surface air temperature in historical and RCP simulations from CanESM2 by Nathan P Gillett (557010)

“…Shaded bands show estimates of the 5–95% uncertainty ranges in the ensemble mean ratios, derived by taking the standard deviation of the ratio from each of the five independent pairs of simulations with and without aerosol changes, dividing by the square root of five (the ensemble size), and multiplying by a Student-<em>t</em> statistic with a cutoff value of 0.05 and four degrees of freedom (one less than the ensemble size). …”

Decrease of dermal markers after <i>Wnt11</i> RNAi. by Gabriela Morosan-Puopolo (211008)

Evaluation of the Acid Baking Technique to Decrease the Phosphorus Content of the Iron Ore by Leonardo Martins da Silva (7425692)

“…We performed a design of experiment (DOE) to investigate the optimal conditions of heating and leaching, which maximize the rate of phosphorus removal. …”

The G357S mutation decreases both activation and termination thresholds for SOICR. by Yingjie Liu (317210)