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421
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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422
Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices
Published 2012“…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …”
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423
Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells
Published 2014“…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …”
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424
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425
Molecular dynamics of CH4/CO2 on calcite for enhancing gas recovery
Published 2022“…These results highlight how the CO2 geometry of adsorption is well defined and characterized by strong interaction, while methane adsorption is quite loose and depicts a very dynamic picture. Focusing on the effect of pressure, RDF peaks intensities increase, although this effect is limited to the 1-5 MPa range. …”
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426
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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427
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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428
Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity
Published 2023“…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …”
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429
Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…Two batches of sensors were tested in this work: i) sensors based on graphene only, and ii) sensors based on graphene and percolating films of Au nanoclusters, each has a thickness of 5 nm. For nanocluster deposition, each graphene sample was fixed on a cryostat finger. …”
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430
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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431
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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432
Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate
Published 2020“…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …”
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433
Flight Scheduling in the Airspace
Published 2016“…In this study, we developed a scatter search (SS) to deal with larger instances. …”
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434
Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications
Published 2022“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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435
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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436
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437
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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438
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439
Modification of Pd/CeO2 catalyst by Atomic Layer Deposition of ZrO2
Published 2016“…Methane-oxidation rates in 0.5% CH4 and 5% O2 were slightly lower on the ZrO2-covered catalyst when both materials were calcined at 673 K but the activity of the ZrO2-modified catalyst did not decrease with catalyst calcination temperature. …”
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440
Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
Published 2012“…Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. …”
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