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Image_5_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.TIF
Published 2020“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”
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282
MMR mutants show decreased mating-type silencing.
Published 2020“…<i>sir1Δ</i> mutant was used as a positive control. <b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”
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Intracameral injections of ATX inhibitor decreases IOP in rabbits.
Published 2012“…Drug treated eyes showed a significant decrease in IOP from the baseline (by 6–7 mm Hg) at 24 and 48 hrs based on paired t-test. …”
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288
Decreased cell stiffness after dissociation of intercellular adhesion.
Published 2014“…Cell stiffness was measured before and after the nanorobotic surgery and decreases from 30.0±1.5 kPa to 20.5±2.8 kPa, respectively. …”
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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer
Published 2015“…Two of the five siRNAs tested were found to efficiently inhibit mRNA of both <i>TMPRSS2-ERG</i> variants and to decrease ERG protein expression. …”
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294
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Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study
Published 2016“…We previously demonstrated that early initiation of sustained low-efficiency dialysis (SLED) followed by daily SLED significantly decreases mortality. …”
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296
Validation of a New Scoring Scale for Behavioral Assessment of L‑Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development
Published 2017“…The rating scale was sensitive enough to highlight a dose-dependent amantadine-mediated decrease (about 2.2-fold) in LID score. …”
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297
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A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population
Published 2015“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”
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