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Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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Tracking spatio-temporal dynamics of harmful algal blooms using long-term MODIS observations of Chaohu Lake in China from 2000 to 2021
Published 2023“…However, environment management policies since 2020 have had a significant and rapid influence in decreasing the lake’s nutrients, which greatly reduced HABs severity in 2020 and 2021. …”
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626
Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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Investigation of Spatiotemporal Variability of Microplastics in Qatar's Cstal Environment
Published 2016“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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Gender Prespecified Sampling for Cost Control
Published 2014“…We find a notable reduction in field costs when field-tested in Qatar. …”
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629
Changes in air quality during the first-level response to the COVID-19 pandemic in Shanghai Municipality, China
Published 2020“…The results showed that air quality improved significantly During-FLR compared with Pre-FLR, with the concentrations of PM2.5, PM10, SO2, NO2, and CO all decreasing significantly. …”
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The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…The hemorrhage-induced vasodilation of the A3 and A4 arterioles was maintained during the post-resuscitation observation period in the CR (+55.3 ± 6.4%) and the vitasol groups (+39.5 ± 5.2%), but remarkably attenuated in the norepinephrine (+9.6 ± 5.8%) and vasopressin (+9.4 ± 8.8) groups. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Chemical characterization and evaluation of antimicrobial and cutaneous wound healing potentials of gold nanoparticles using Allium saralicum R.M. Fritsch
Published 2020“…© 2020 John Wiley & Sons, Ltd. The use of herbal medicines dates back a long way in history. …”
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Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar
Published 2014“…In contrast to Western countries, we report a varied genotypic profile of HPV with a high prevalence of low-risk HPV genotype 81 among the Arab women residing in Qatar.…”
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Evaluation of the inhibition performance of piperazine-based polyurea towards mild steel corrosion: The role of keto-enol tautomerization
Published 2022“…The presence of PUCorr at 100 ppm decreases the corrosion current density from 30.3 to 3.05 μA/cm2 in 0.5 M NaCl at room temperature, exhibiting a remarkable inhibition efficiency of 94.5%. …”
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Therapeutic potential of resveratrol in covid-19-associated hemostatic disorders
Published 2021“…Dysfunctions of endothelial cells and platelets are tightly linked in contributing to the systemic inflammatory response that appears to be both a cause and a consequence of COVID-19-associated coagulation disorders and thrombotic events. …”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…ObjectiveTo objectively evaluate technical skill acquisition in hypospadias repair procedures during surgical training using noninvasive wearable sensor technology. MethodsWe combined subjective video evaluations with objective electromyography (EMG) measurements in a hands-on hypospadias training course. …”
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Financial Intermediaries and Capital Market Development in Nigeria
Published 2018“…The result revealed that in the long run, credit to private sector and money supply will lead to an increase in capital market development while banks total savings and government expenditure results to a decrease in capital market development in the long run. …”
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