Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Alhujaily, Muhanad

“…Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. …”
Get full text
Get full text
Get full text

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Uncertainty from past data inputs and model estimation was propagated throughout analyses by taking 1000 draws for past and present fertility estimates and 500 draws for future forecasts from the estimated distribution for each metric, with 95% uncertainty intervals (UIs) given as the 2·5 and 97·5 percentiles of the draws. To evaluate the forecasting performance of our model and others, we computed skill values—a metric assessing gain in forecasting accuracy—by comparing predicted versus observed ASFRs from the past 15 years (2007–21). …”
Get full text
Get full text
Get full text

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Uncertainty from past data inputs and model estimation was propagated throughout analyses by taking 1000 draws for past and present fertility estimates and 500 draws for future forecasts from the estimated distribution for each metric, with 95% uncertainty intervals (UIs) given as the 2·5 and 97·5 percentiles of the draws. To evaluate the forecasting performance of our model and others, we computed skill values—a metric assessing gain in forecasting accuracy—by comparing predicted versus observed ASFRs from the past 15 years (2007–21). …”
Get full text
Get full text
Get full text

Microstructure, wear and corrosion characteristics of Cu matrix reinforced SiC–graphite hybrid composites by Jamwal A.

“…Copper matrix composites with SiC-graphite reinforcement (0, 2.5,5, 7.5 and 10 wt.%) were prepared by stir casting process. …”
Get full text
Get full text

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
Get full text
Get full text
Get full text

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
Get full text
Get full text
Get full text

Performance assessment of renewable energy-fed three-phase grid-connected voltage source converters and boost inverters during DC side faults by Elserougi, A.

“…The simulation results elucidate a significant decrease in the DC fault current in case of boost inverter due to its blocking capability.…”
Get full text
Get full text

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …”
Get full text
Get full text
Get full text

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. …”
Get full text
Get full text
Get full text

Impact of fines type on gas flow using 3D micro-computed tomography by Al-Raoush, Riyadh

“…Therefore, there is a need to model and quantify fines impact on multi-phase flow using 3D reconstruction to better understand gas recovery systems. …”
Get full text
Get full text

Analysis of bioconvection and oxytactic microorganisms in a porous cavity with nano-enhanced phase change materials and quadrant heater: Application of support vector regression ba... by Hussain, Shafqat

“…The Galerkin finite element method (GFEM) is employed to compute the governing equations for the considered system by developing a computer code. The study is performed for wide range of parameters as aspect ratio, Darcy number, Hartmann number, nanoparticle fraction, bioconvection Rayleigh number and natural convection Rayleigh number were tested. …”
Get full text
Get full text

Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide-based gels: Rheological and molecular simulation study by Hamza A.

“…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …”
Get full text
Get full text
Get full text

Growth performance, intestinal histomorphology, gut microflora and ghrelin gene expression analysis of broiler by supplementing natural growth promoters: A nutrigenomics approach by Gilani, S.M.H.

“…In an epoch of escalating number of antibiotic-resistance bacteria, there is a dire need to develop efficient and novel feeding strategies for animal nutrition as alternatives to antibiotics. …”
Get full text
Get full text
Get full text

The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: Ab initio calculations by Shalabi, A.S.

“…The calculated Stokes shifted optical transition bands suggest that laser activity is relatively weak and fades quickly as the coordination number of the surface ions decreases from 5 (flat) to 4 (edge) to 3 (corner). …”
Get full text
Get full text

A Reduction in Maximal Incremental Exercise Test Duration 48 h Post Downhill Run Is Associated with Muscle Damage Derived Exercise Induced Pain. by Chrismas, Bryna C R

“…Conclusion: EIMD resulted in premature termination of a MIE test (decreased TTE), which was associated with EIP, MVC, and VA. …”
Get full text
Get full text

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

“…We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. …”
Get full text
Get full text
Get full text

Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial by Meng W.

“…Prolonged dilation (300 s) with a 10 mm diameter balloon decreases the occurrence of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). …”
Get full text
Get full text

Antagonistic Effects of Trichoderma harzianum Isolates against Ceratocystis radicicola: pioneering a Biocontrol Strategy against Black Scorch Disease in Date Palm Trees by Al-Naemi, Fatima A.

“…The aim of this study was to develop a method of biological control through the isolation, identification and examination of the effectiveness of bioagents in controlling black scorch disease. …”
Get full text
Get full text

Artificial weathering and accelerated heat aging studies on low-density polyethylene (Ldpe) produced via autoclave and tubular process technologies by Luyt, A. S.

“…In particular, a mechanism of chain scission/branch-ing that resulted in crosslinking was assumed for the neat polyethylenes, after combining the decrease of molecular weight observed in the GPC analysis with the increase in Young's modulus after UV exposure. …”
Get full text
Get full text

VANET-based smart navigation for emergency evacuation and special events by Elbery A.

“…The objective of the proposed system is to clear the network in a shorter time by better utilizing the network resources while taking into consideration the road capacities. …”
Get full text
Get full text