DataSheet_1_Nationwide Trends of Pediatric Obesity and BMI z-Score From 2017-2021 in China: Comparable Findings From Real-World Mobile- and Hospital-Based Data.docx by Yan Yang (33204)

“…The trend of obesity prevalence remained stable with slight decrease, but COVID-19 lockdown caused a significant increase of 1.86% in 2020. …”

Mutations at p53 binding sites augment PIK3CA promoter activity. by Snehal M. Gaikwad (279479)

“…Representative bioluminescent images of the mice bearing tumors of A2780-MPFT3 cells. Mouse from control and treated group exhibited specific [Fig. 5e3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 5e3 (post-treatment)].…”

Table1_Effect of botanical drugs in improving symptoms of hypertensive nephropathy: Analysis of real-world data, retrospective cohort, network, and experimental assessment.XLSX by Jia-Ming Huan (15185389)

“…</p><p>Results: A total of 14 botanical drugs and five symptom communities were obtained from real-world clinical data. …”

Image_1_Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infa... by Yang Xiao (146335)

“…., opiates, benzodiazepines, P2Y₁₂ antagonist, propofol) need to be identified in preclinical models.</p><p>Methods: Here, we examined the efficacy of promising cardioprotective compounds [fingolimod (Fingo), empagliflozin (Empa), melatonin (Mela) and nicotinamide riboside (NR)] administered i.v. as bolus before start ischemia. …”

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations by Hafiz Muhammad Ali (554920)

“…Our aim is to demonstrate <i>in vitro</i> and <i>in vivo</i> molecular and cellular effects of siRNA on <i>RET/PTC3</i> knockdown for therapeutic application.First, we established a novel cell line stably expressing <i>RET/PTC3</i> junction oncogene, named RP3 which was found tumorigenic in nude mice compared to NIH/3T3 mouse fibroblasts. …”

Data_Sheet_1_Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces... by Yang Xiao (146335)

“…., opiates, benzodiazepines, P2Y₁₂ antagonist, propofol) need to be identified in preclinical models.</p><p>Methods: Here, we examined the efficacy of promising cardioprotective compounds [fingolimod (Fingo), empagliflozin (Empa), melatonin (Mela) and nicotinamide riboside (NR)] administered i.v. as bolus before start ischemia. …”

Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen <i>Ehrlichia chaffeensis</i> by Nan Duan (4837896)

Presentation 1_Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study.pdf by Brittany McFeeley (21104825)

“…Study 1.0 participants indicated a decrease in cognitive activities since the start of COVID-19 restrictions, whereas those in Study 2.0 reported an increase in cognitive activities.…”

Modulating the excitability gradient changes domino speed. by Jennifer Creaser (9427932)

“…Scale bar: 500 <i>μ</i>V, 5s. Panel <b>c</b> shows the mean recruitment time of model simulations of the network with different values of excitability gradient <i>δν</i>. …”

Schematic of experimental paradigms. by Shiva Farashahi (5018381)

“…A central yellow bar represented the probability of reward (between 0.5 and 1.0), while the peripheral arc indicated the amount of reward. …”

Study on the properties of oil-water interface after the interaction between ionized water and naphthenic acid by Qin Guowei (22155073)

“…The results show that after the action, the interfacial tension of oil and water continues to decrease, and 1/3 ionized water (salinity diluted to 1/3 of the prepared ionized water, 1253 ppm) decreases to a maximum of 50.89%, while 1/5 ionized water (752 ppm) only decreases 14.40%; the thickness of the oil-water interface film decreases with the salinity of ionized water, but the decrease increases after 1/3 ionized water. …”

RSK2 regulates cell cycle progression in response to genotoxic stress. by Han Chi Lim (439624)

“…RSK2 WT (A) and KO (B) MEFs were treated with 0.5 µM AD at various time points, and the cells were fixed and stained with propidium iodide, followed by flow cytometry analysis. …”

IL6/STAT3 modulates estrogen-induced GREB1 transcriptional activity in breast cancer cells. by Mingli Liu (304361)

“…The samples were treated with E2 as indicated before assaying for luciferase activity. As shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046410#pone-0046410-g005" target="_blank">Figure 5G</a>, STAT3-C decreases GREB1 transcription by approximately 39%. …”

MCF-DCIS clusters co-cultured with 3D HMF and with 2D HMF. by Kyung Eun Sung (467005)

“…<p>(A) MCF-DCIS clusters (red and outlines) co-cultured with 3D HMF and neutralizing HGF antibody at 0.5 μg/ml (3D HMF-HGF). …”

Actin polymerization lead to YAP de-phosphorylation and nuclear localization. by Pradeep Reddy (371909)

“…<p>A. The levels of pYAP are decreased after treatment with jasplakinolide. …”

Figure 6 by Chris Murgatroyd (373352)

“…<p>A, DZNep treatment inhibited Suz12 occupancy and Mecp2 recruitment at the <i>Avp</i> enhancer during hypothalamic-like differentiation of EB5 cells. …”

Empagliflozin Reduces Liver Fat in Diabetic and Nondiabetic Subjects by Siham Abdelgani (17756772)

Agmatine treatment reduced the gliosis activation following SCI. by Yu Mi Park (275600)

“…</b> The GFAP expressions were substantially decreased after SCI in the Agm treated group (<i>n</i> = 5) compared with the EC group (<i>n</i> = 5). …”

Steroidogenic programme is differently regulated in the XX and XY gonads of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> mice. by Alejo Torres-Cano (12878169)

“…<p>(A) Immunostaining for NR5A1 (red) and nuclear DAPI staining (blue), using sections of gonads from XY and XX control and <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> E14.5 mice. …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”