Image_1_Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy.TIF by Chengzhi Yang (2585791)

“…</p>Results<p>Plasma apelin levels were significantly lower in patients with OHCM than those in control subjects (96.6 ± 34.3 vs. 169.4 ± 62.5 μg/L, p < 0.001). When patients with OHCM were divided into two groups according to the mean value of plasma apelin, patients with lower apelin levels (plasma apelin ≤ 96.6 μg/L) had greater septal wall thickness (SWT; 25.6 ± 5.5 vs. 23.2 ± 4.3 mm, p = 0.035) and less right ventricular end-diastolic diameter (RVEDD; 20.4 ± 3.3 vs. 23.0 ± 3.6 mm, p = 0.001). …”

Table_1_Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy.DOCX by Chengzhi Yang (2585791)

“…</p>Results<p>Plasma apelin levels were significantly lower in patients with OHCM than those in control subjects (96.6 ± 34.3 vs. 169.4 ± 62.5 μg/L, p < 0.001). When patients with OHCM were divided into two groups according to the mean value of plasma apelin, patients with lower apelin levels (plasma apelin ≤ 96.6 μg/L) had greater septal wall thickness (SWT; 25.6 ± 5.5 vs. 23.2 ± 4.3 mm, p = 0.035) and less right ventricular end-diastolic diameter (RVEDD; 20.4 ± 3.3 vs. 23.0 ± 3.6 mm, p = 0.001). …”

Simultaneous measurements of cytosolic and mitochondrial Mg²⁺ concentration changes. by Yutaka Shindo (209437)

“…Administration of 5 µM FCCP induced a rapid increase in [Mg²⁺]_cyto and a gradual decrease in [Mg²⁺]_mito. …”

Development of an <i>in vitro</i> media perfusion model of <i>Leishmania major</i> macrophage infection by Alec O’Keeffe (7037294)

“…Media perfusion also decreased amastigote replication and both macrophage phagocytosis (by 44±4% under slow flow and 57±5% under fast flow compared with the static condition) and macropinocytosis (by 40±4% under slow flow and 62±5% under fast flow compared with the static condition) as measured by uptake of latex beads and pHrodo Red dextran.…”

Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia by April C.E. van Gennip (10993229)

“…</p> <p><b>Results </b>After a mean follow-up of 9.0 years, 147(1.4%) individuals with diabetes and 412(0.5%) controls had incident dementia. …”

DataSheet1_Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita.PDF by Concetta Altamura (13232397)

“…In this study, we tested the ability of niflumic acid (NFA), a commercial nonsteroidal anti-inflammatory drug, to act as a pharmacological chaperone on trafficking-defective MC mutants (A531V, V947E). …”

Fluoride exposure and its interaction with <i>ATP2B1</i> polymorphism in the alteration of lipid metabolism in adults by Junhua Wu (154979)

“…There was an interaction between urinary fluoride which was lower than 0.9 mg/L and rs7136259 for carriers of T allele (OR = 2.67 [95% CI, 1.34–5.31]) in serum ApoA1 decrease. It indicated fluoride exposure might be associated with the alteration of serum ApoA1 and ApoB in adults.…”

NCA-1 Activity Is Required for Normal Synaptic Transmission at NMJs by Edward Yeh (42793)

“…Individual results are shown in black, mean ± SEM in gray, for recordings at 5 mM and 1 mM extracellular Ca²⁺.…”

Exploring the Scope of the 29G12 Antibody Catalyzed 1,3-Dipolar Cycloaddition Reaction by Jonathan D. Toker (2668999)

“…Given the unique nature of 29G12 as a protein biocatalyst for this chemical reaction, we have investigated both the substrate specificity and mechanistic parameters of the 29G12-catalyzed process. …”

Diversity, distribution and dynamics of large trees across an old-growth lowland tropical rain forest landscape by David B. Clark (7846700)

“…Large trees accounted for 2.5% of stems and ~25% of mean basal area and Estimated Above-Ground Biomass, and produced ~10% of the estimated wood production. …”

Image_2_Blood Lead Level Is Negatively Associated With Bone Mineral Density in U.S. Children and Adolescents Aged 8-19 Years.tif by Aiyong Cui (12984401)

“…</p>Methods<p>We analyzed 5,583 subjects aged 8-19 years (mean age, 13.49 ± 3.35 years) from the NHANES 2005-2010. …”

Image_1_Blood Lead Level Is Negatively Associated With Bone Mineral Density in U.S. Children and Adolescents Aged 8-19 Years.tif by Aiyong Cui (12984401)

“…</p>Methods<p>We analyzed 5,583 subjects aged 8-19 years (mean age, 13.49 ± 3.35 years) from the NHANES 2005-2010. …”

Changes in mitochondrial protein expression levels following ND-13 treatment. by Lior Molcho (4898791)

“…SDHAF4 protein levels increased after ND-13 treatment (A, FC = 107.4, p<0.001). Ubiquinone protein levels decreased after ND-13 treatment (B, FC = 3.5, p<0.01). …”

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…Error bars represent means ± SD for five independent experiments (> 1,200 cells per condition). …”

Loss of pancreatic cell identity in <i>Pdx1-Cre; Ctnnb1</i>^{<i>tm1Mmt/+</i>} pancreas. by Jose Luis Muñoz-Bravo (3220134)

“…<p>Hematoxylin/eosin staining of E13.5 pancreatic sections showing reduced branching and multiple dilations in the pancreatic epithelium of <i>Pdx1-Cre; Ctnnb1</i>^{<i>tm1Mmt/+</i>} pancreata (A) compared to control pancreata (B). …”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…<p>(<b>A–D</b>) mRNA expression levels of <i>Igf1</i>, <i>Igf1r</i>, <i>Igfbp2</i> and <i>Igfbp3</i> were analyzed by qRT-PCR in <i>Igf1^+/+</i> (open circles) and <i>Igf1^−/−</i> (closed circles) mice at E15.5 and E18.5 (n = 8), P5, P15, P30, P60 and P90 (n = 6). …”

Astragaloside IV regulated BBB permeability and ROS levels. by Yixin He (466799)

“…All data are presented as mean±standard error of the mean. n = 5 in each group. *, p<0.05; **, p<0.01; ***, p<0.001. …”

Data_Sheet_1_The Role of Sustained Photoprotective Non-photochemical Quenching in Low Temperature and High Light Acclimation in the Bloom-Forming Arctic Diatom Thalassiosira gravid... by Thomas Lacour (5877947)

“…We investigated T. gravida physiological plasticity growing it at two temperatures (0 and 5°C) and under different light intensities typically found in its natural environment. …”

Pancreatic islets function normally in double transgenic Ins2-rtTA/pBI-cAMP mice induced to express the cAMP reporter in pancreatic islet β-cells. by Joung Woul Kim (271961)

“…Double transgenic mice, subjected to a Glucose Tolerance Test before (○), and 1 week after (•) induction of the cAMP reporter showed similar rise and fall in plasma glucose (mean±s.e.m.; n = 5 mice). …”

LLIF IN THE CORRECTION OF DEGENERATIVE SCOLIOSIS IN ELDERLY PATIENTS by VLADIMIR SERGEEVICH KLIMOV (10418250)

“…Results Back pain, measured according to the Visual Analogue Scale (VAS), decreased from 5.9/6 (4;8) (format – mean/median (1;3 quartile)) to 2.6/3 (1;3) points (p <0.0001). …”