DAF-16 contributes to inhibition of <i>mec-4d</i>–dependent AVM degeneration associated with reduced IIS signaling. by Andrea Calixto (16070)

“…Scale bar, 5 µm. (F–G) <i>mec-4d</i> worms were treated from the time of hatching with the ROS scavenger trolox (100 µm) and ascorbic acid (AA, 50 mM); after 72 hours both somas (F) and axons (G) were protected several fold compared to control nematodes (mean value for each category is shown; error bars [<1%] not included; N = 3 of 30 worms each per group; *p<0.005 by Student's t test compared with control for the SoW and AxW category).…”

Ammonia has dual functions in autophagy regulation. by Zhiyuan Li (205620)

“…<p>(A) Acridine orange staining shows that 5–10 mM of NH₄Cl increase the vesicular pH in cells. …”

Multiscale spatial patterns of species diversity and biomass together with their correlations along geographical gradients in subalpine meadows by Manhou Xu (640734)

“…<i>γ</i>-Diversity demonstrated quadratic function changes that were initially incremental and then decreased with increasing longitude, elevation, and latitude from 37.5° to 40°. …”

Table_1_Genetic variation for terminal heat stress tolerance in winter wheat.xlsx by Jianming Fu (500731)

DataSheet1_Bayesian denoising algorithm dealing with colored, non-stationary noise in continuous glucose monitoring timeseries.docx by Nunzio Camerlingo (9394596)

“…</p><p>Results: On D_S1, BD allows reducing the root-mean-square-error (RMSE) from 8.10 [6.79–9.24] mg/dL to 6.28 [5.47–7.27] mg/dL (median [IQR]); on D_S2, RMSE decreases from 6.85 [5.50–8.72] mg/dL to 5.35 [4.48–6.49] mg/dL. …”

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles by Guy M. Quanrud (8621454)

Autophagic blockage by metformin-loaded PLGA nanoparticles causes cell cycle arrest of HepG2 cells - supplementary figure by Chen Chen (6544)

Insulin Resistance in Relation to Lipids and Inflammation in Type-2 Diabetic Patients and Non-Diabetic People by Ying-Mei Feng (2609680)

“…</p><p>Methods</p><p>We studied 798 Chinese patients with type-2 diabetes (53.6% women; mean age, 60.6 years) admitted to a tertiary referral centre and 1060 white Flemish (50.5%; 51.1 years) randomly recruited in Northern Belgium. …”

DataSheet_1_Regional Cerebral Associations Between Psychometric Tests and Imaging Biomarkers in Alzheimer’s Disease.docx by Dennis M. Hedderich (9237437)

“…A total of 76 patients (mean age 68.4 ± 8.5 years, 57.9% male) with early AD (median global clinical dementia rating (CDR) score = 0.5, range: 0.5–2.0) were studied. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Differential -/-WT and -/-C3S expression profiling reveals genes acutely responsive to Stat3 oxidation. by Michela Grillo (9866772)

“…Significant DE in each comparison (e.g. -/-WT basal v oxidation) scores 1 (increase), -1 (decrease) or 0 (no significant change). …”

Table_8_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx by Yujia Zhang (757462)

“…The cell morphology altered dramatically 72 h after transfection, becoming rounder, with a decrease in cell number. BCP exhibited the potential to dramatically increase PC-12 cell viability while protecting cell morphology. …”

Table_1_Environmental and Biological Determinants of Algal Lipids in Western Arctic and Subarctic Seas.DOCX by Vincent Marmillot (9912234)

“…Decreasing pH had a negative effect on EPA and MUFA proportions, and DHA proportions tended to decrease with higher temperature. …”