Polyunsaturated fatty acid synthesis de novo is required for calcium release in vascular smooth muscle by Nicola Irvine (591917)

“…<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in phenylepherine (PE)- induced vasoconstriction in human femoral artery,<br>and in rat aorta and mesenteric arteries. …”

Spontaneous mitotic recombination depends on normal CTD phosphorylation. by Tiffany Sabin Winsor (403023)

“…Deletion of <i>CTK1</i> causes a 5–20 fold decrease in recombination rates at three different heteroalleles.…”

Comparison of substrate metabolism in brown and white preadipocytes and adipocytes. by Barry R. Bochner (226699)

“…<p>Normalized optical-density scores representing nutrient metabolism, showing the greatest differences between white fat (top) and brown fat (bottom) cells in either an undifferentiated (gray bars) or differentiated (black bars) state. Included are a) wells that cause no change (1, negative control), b) nutrients that are high in brown preadipocytes and decrease upon differentiation (2, α-D-glucose-1-phosphate; 3, D-glucose-6-phosphate; 4, D-fructose-6-phosphate; 5, glycogen), c) a similarly behaved nutrient that is high in white fat (6, hexanoic acid), d) nutrients that decrease during differentiation of both cell types (7, dextrin; 8, butyric acid), and e) nutrients that increase upon white fat differentiation (9, L-leucine; 10, Leu-Leu; 11, succinamic acid, 12. acetoacetic acid). …”

Antihyperglycemic and neuroprotective effects of Wattakaka volubilis (L.f.) Stapf root against streptozotocin induced diabetes by Hajira Banu Haroon (12847493)

“…All the alcohol extract treated animals, showed a significant decrease in serum glucose level (P<0.001), and overall decrease in the severity of diabetic neuropathy. …”

Effect of amikacin-humic acid combination on <i>Acinetobacter baumannii</i> biofilm: an <i>in vitro</i> and <i>in silico</i> study by Seetha Lakshmi Rajangam (19921021)

Stress-induced remodeling of translatomes. by Iván Ventoso (125168)

“…A representative member of this group is the HSPA5 (the BiP chaperone) mRNA. …”

Table_1_Molecular epidemiology and antibiotic resistance profiles of invasive Haemophilus influenzae from Norway 2017–2021.XLSX by Ragnhild Tønnessen (408372)

“…Incidence rates of invasive Hi disease in Norway ranged from 0.7 to 2.3 per 100,000 inhabitants/year (mean 1.5 per 100,000) and declined during the COVID-19 pandemic. …”

Data_Sheet_1_Molecular epidemiology and antibiotic resistance profiles of invasive Haemophilus influenzae from Norway 2017–2021.docx by Ragnhild Tønnessen (408372)

“…Incidence rates of invasive Hi disease in Norway ranged from 0.7 to 2.3 per 100,000 inhabitants/year (mean 1.5 per 100,000) and declined during the COVID-19 pandemic. …”

Supplementary Material for: Evolution of growth following anti-TNF-α therapy in paediatric Crohn’s disease: data from the Swiss IBD Cohort Study by figshare admin karger (2628495)

“…Height velocity z-scores showed a significant increase across both genders. Factors contributing to a decreased height z-score included male sex, age 10 and below at diagnosis, a concomitant corticosteroid treatment and a top-down treatment strategy. …”

Mechanical AVR With Y-Incision Aortic Annular Enlargement by Bo Yang (104813)

“…</p> <p><strong>Patient Selection</strong> </p> <p>The patient was a female with a body height of 155 cm (5’11”), a body weight of 126 kg (277 pounds), a BMI of 52.5 kg/m2, and a body surface area of 2.15 m2. …”

Salinomycin impairs HCC cell survival. by Johannes Klose (562050)

“…<p>HepG2 and Huh7 cells were exposed to increasing concentrations of Salinomycin (1, 2, 5 and 10 µM) for 24 hours. (<b>A</b>) Cell viability was assessed by MTS-assay; high concentrations of Salinomycin led to significantly decreased viability of both cell lines (n = 5). …”

Data_Sheet_1_Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na+ and hyperpolarization-activated cation currents.docx by Te-Yu Hung (15861305)

“…However, CRS strongly decreased the strength (i.e., Δarea) of the nonlinear window component of I_Na (I_Na(W)), which was activated by a short ascending ramp voltage (V_ramp); the subsequent addition of deltamethrin (DLT, 10 μM) counteracted the ability of CRS (100 μM, continuous exposure) to suppress I_Na(W). …”

Mcl-1 plays critical roles in regulating the sensitivity of melanoma cells to apoptosis induced by EGb761. by Yufang Wang (105742)

“…<p>(A) Knockdown of Mcl-1by siRNA decreases the levels of Mcl-1expression. …”

Data_Sheet_1_Severe Disease in Patients With Recent-Onset Psoriatic Arthritis. Prediction Model Based on Machine Learning.docx by Rubén Queiro (8445777)

“…Objectives<p>To identify patient- and disease-related characteristics that make it possible to predict higher disease severity in recent-onset PsA.</p>Methods<p>We performed a multicenter observational prospective study (2-year follow-up, regular annual visits). …”

DataSheet2_Rejuvenation of Helicobacter pylori–Associated Atrophic Gastritis Through Concerted Actions of Placenta-Derived Mesenchymal Stem Cells Prevented Gastric Cancer.PDF by Jong Min Park (3387806)

“…Significant changes in various pathological parameters including inflammation, gastric atrophy, erosions/ulcers, and dysplastic changes were noted in the control group (p < 0.01), but these were all significantly reduced in the PD-MSC/CM-treated groups. Lgr5+, Ki-67, H⁺/K⁺-ATPase, and Musashi-1 expressions were all significantly increased in the treated animals, while inflammatory mediators, MMP, and apoptotic executors were significantly decreased in the PD-MSC group compared to the control group (p < 0.001). …”

DataSheet1_Rejuvenation of Helicobacter pylori–Associated Atrophic Gastritis Through Concerted Actions of Placenta-Derived Mesenchymal Stem Cells Prevented Gastric Cancer.DOCX by Jong Min Park (3387806)

“…Significant changes in various pathological parameters including inflammation, gastric atrophy, erosions/ulcers, and dysplastic changes were noted in the control group (p < 0.01), but these were all significantly reduced in the PD-MSC/CM-treated groups. Lgr5+, Ki-67, H⁺/K⁺-ATPase, and Musashi-1 expressions were all significantly increased in the treated animals, while inflammatory mediators, MMP, and apoptotic executors were significantly decreased in the PD-MSC group compared to the control group (p < 0.001). …”

MSC^hUCB1 express neural specific markers suggesting neural differentiation. by Murni Tio (197880)

“…The MAPK pathway is down-regulated as a consequence of differentiation as shown by decreasing levels of P-ERK1/2 correlated to increasing length of differentiation. …”

Reduction in DRG neuronal numbers following error correction. by Ayal Ben-Zvi (438134)

“…A significant decrease in neuron number is observed in the Sema3A^−/−:BAX^−/− embryos as compared to Sema3A^+/+: BAX^−/−, which correlates with error correction (P = 0.0169). …”

Demography of normoxic and hypoxic flies by Paul Vigne (373124)

“…</p> <p>(A) Survivorship analysis.</p> <p>Hypoxia decreased the mean life span from 33.6±0.8 days (n = 79) to 6.3±0.1 days (n = 282).…”

COMPARISON OF RESPONSE SURFACE METHODOLOGY (RSM) AND ARTIFICIAL NEURAL NETWORKS (ANN) TOWARDS EFFICIENT OPTIMIZATION OF FLEXURAL PROPERTIES OF GYPSUM-BONDED FIBERBOARDS by Morteza Nazerian (5256530)

“…The weight ratios of fiberglass (at three levels 0, 3 and 6%), bagasse fiber (at three levels 0, 7.5 and 15%) and kenaf fiber (at three levels 0, 7.5 and 15%) to gypsum are used to make the gypsum-bonded fiberboard with the nominal density 1.10 g.cm-3 . …”