Destabilization of dystrophin and β-DG by Lis1-Nde1 deficiency. by Ashley S. Pawlisz (52227)

“…<p>(A) Total protein extracts from cerebral cortices of E12.5 embryos were examined by immunoblotting. …”

Cortical and subcortical regions feature distinct early and late responses during audition. by Sarah H. McGill (22505225)

“…<p>The differences between the mean peristimulus spectrograms of maximum-intensity auditory stimulus trials (65.7 dB) and no-stimulus trials (63.5 dB) are shown here. …”

Lineage tracing of NCCs. by Toshihiro Inubushi (647748)

“…<p>(<b>A</b>) Whole-mount fluorescence images of <i>Tmem2</i>^<i>CKO</i><i>;ZsGreen</i> and control embryos at E9.5. …”

Supplementary Figure 4 Effects of enriched environment on behavior of adult mice in the open field test by Fumio Soeda (9738569)

“…<p>The open field test consisted of two 5-minute trials in mice at 30 weeks old. In the second trial, ambulation (each of five 1-min periods) in the enriched group was significantly decreased compared to the standard group (a, left). …”

DC Response – recurrent dynamics. by Audrius V. Avizienis (145238)

“…<p>(a) Time traces of current response to 1 V DC bias show large current increases and decreases at all time scales around a mean of 5.81 µA (172 kΩ); shorter time traces (ii–iii) are subsets of (i). …”

Glutamate accelerates synaptic release from cone terminals. by Skyler L. Jackman (222281)

“…(C) Time-course of FM1-43 fluorescence decreases from cone terminals in darkness (<i>n</i> = 27, error bars are obscured by the data points) and 2 mM glutamate (<i>n</i> = 5). …”

Holding potential-sensitive K⁺ currents are sensitive to 4-AP. by Snezana Levic (336804)

“…<p>(<b>A</b>) An example of whole cell current recorded from apical HCs at E12 and E18 showing TEA and 4-AP-sensitive components, using the protocol described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029005#pone-0029005-g001" target="_blank">Figure 1</a>. …”

Collagen type I monomers increase Phospho-Akt expression via PI3kinase activation. by Mirjam Stahl (487952)

“…Basal, constitutive phospho-Akt expression was high in AM from each 5 healthy donors and IPF patients. A non-selective inhibitor of PI3kinase, LY294002 (50 μM, DMSO as control), abrogated CCL18 production following stimulation with collagen type I monomers and decreased significantly spontaneous CCL18 production of AM (Panel <b>B</b>). …”

Characterization of the sexual development of deletion mutants for spore-enriched proteins. by Mingwei Huang (788799)

“…Panels show the periphery of a spot of a cross on V8 plate for 24h at 25°C. …”

Comparative Component Analysis of Exons with Different Splicing Frequencies by Shiqin Song (264631)

“…Beyond the conventional classification for alternatively spliced exons (ASEs) and constitutively spliced exons (CSEs), we have classified exons from alternatively spliced human genes and their mouse orthologs (12,314 and 5,464, respectively) into four types based on their splicing frequencies. …”

The Essential Nucleolar Yeast Protein Nop8p Controls the Exosome Function during 60S Ribosomal Subunit Maturation by Marcia C. T. Santos (215784)

“…Although depletion of Nop8p in yeast cells leads to premature degradation of rRNAs, the biochemical mechanism responsible for this phenotype is still not known. In this work, we show that the Nop8p amino-terminal region mediates interaction with the 5.8S rRNA, while its carboxyl-terminal portion interacts with Nip7p and can partially complement the growth defect of the conditional mutant strain <em>Δnop8/GAL::NOP8</em>. …”

Average velocity of FRDA mice. by Sara Anjomani Virmouni (627000)

“…<p>(<b>a</b>) YG8R and YG22R displayed significantly decreased average velocity compared to B6 and Y47R controls when both male and female values were taken together (<i>n</i> = 10 mice per genotype). …”

Experimental detection of critical points in fibers treated with blebbistatin. by Fabio C. Minozzo (189129)

“…<p>(A) Superimposed contractions, showing the force decay during shortening while the fiber was activated with pCa²⁺ 4.5- (solid line), and then treated with blebbistatin (dashed line), with the corresponding fiber length changes. …”

Competition of SP-D binding to gp120 by hexoses. by Jens Madsen (391091)

“…Each trace indicates the response units recorded at a given concentration of SP-D (10, 5, 2.5, 1.25, and 0.625 µg/mL) in 5 mM CaCl₂-containing (HSC) buffer (traces are in order of the highest to lowest concentration). …”

Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye - Fig 6 by Whitney Shatz (2487895)

“…Data are reported as the mean SD; Trace findings were assigned a value of 0.5. …”

The ACD regulators Par3, Scribble and Gpsm2 are not required for erythroid enucleation during stress erythropoiesis. by Christina B. Wölwer (827149)

“…Graphs showing enucleation efficiencies 5h post sort quantified by LSR II. Data represent the mean (+/- SD) of 3 independent experiments. …”

Data_Sheet_1_Association of Gut Microbiota With Metabolism in Rainbow Trout Under Acute Heat Stress.docx by Changqing Zhou (175208)

“…In the current study, the optimal growth temperature (16°C) of rainbow trout was used as the control group, while the fish treated at 22.5°C, 23.5°C, and 24.5°C for 24 h, respectively, were the treatment groups. …”

Image_1_Climate Variability Rather Than Livestock Grazing Dominates Changes in Alpine Grassland Productivity Across Tibet.TIFF by Meng Li (79487)

“…Our results revealed that Tibet’s climate got warmer and wetter, and grazing intensity decreased after starting the project. Mean ANPP increased at approximately 81% of the sites, on average from 27.0 g C m^–2 during 2000–2008 to 28.4 g C m^–2 during 2009–2017. …”

Table_1_Evaluation of the Direct Effect of Bilateral Deep Brain Stimulation of the Subthalamic Nucleus on Levodopa-Induced On-Dyskinesia in Parkinson's Disease.docx by Jiping Li (469560)

“…The postoperative levodopa equivalent daily dose (LEDD) (823.1 ± 201.5 mg/day) was not significantly changed from baseline (844.6 ± 266.1 mg/day, P = 0.348), while the UDysRS on-dyskinesia subscores significantly decreased from 24 (10–58) to 0 (0–18) [median (range)] after STN stimulation (P < 0.0001). …”

The effect of mycophenolic acid (MPA) and guanosine (Gua) on HCV infectious progeny production and intracellular nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…<p>(a) Huh-7.5 reporter cells were infected with HCVp0 at an initial MOI of 0.1–0.2 TCID₅₀/cell, in the absence or presence of the MPA and Gua concentrations indicated in the upper box. …”