Interaction between the N-terminus of both caspase 8 and SPARC are required to reduce cell viability and enhance apoptosis. by Mahbuba Rahman (198499)

“…<p><b>A–B</b>) Cell viability further decreased in MIP/SP and MIP/SP-N after transfection with wild-type caspase 8 and 5-FU treatment, relative to empty vector (EV, control): MIP/SP: 77.2±3.8 (EV) vs. 59.1±1.5% (caspase 8) (p<0.005); MIP/SP-N: 68.8±4.8 (EV) vs. 50.6±3.6% (caspase 8) (p = 0.04). …”

Data_Sheet_1_Are there effects of light exposure on daytime sleep for rotating shift nurses after night shift?: an EEG power analysis.docx by Soonhyun Yook (10769833)

“…We also observed that light exposure during daytime sleep could additionally decrease N2 sleep spindle activity and N3 waves in the last sleep cycle.…”

Sustainable mobility at the EU level – in the new transport white paper by Tamas Fleischer (409919)

“…Funded by the European Commission in FP7. Szentendre, Hungary, 5/6 May 2011</p> <p>The main message of the contribution in four points:</p> <p>(1) The environmental targets for 2050 (sixty percent emission decrease, oil dependence decrease) are based on a very progressive vision, clear target.…”

Sperm beat frequency and CA-activity in CA ^−/− mice. by Petra M. Wandernoth (149629)

“…Within the first 20 seconds after the addition of bicarbonate, the beat frequency of wild-type sperm (solid line) increases from 2.81±0.17 Hz to 6.13±0.35 Hz and frequency of CA IV^−/− sperm from 2.92±0.17 Hz to 5.57±0.18 Hz (<i>n</i> = 10). <b>C</b>, Sperm of CA IV^−/− mice show a decreased response to CO₂. …”

Model for the Differentiation of the HMS. by Caleb Gonzalez (270214)

“…<p>(A) We suggest that differentiation of the HMS results from the convergence of three events: acquisition of a DNA double-strand break (DSB) or double-strand end (DSE, one end of a DSB); induction of the SOS DNA-damage response; and induction of the RpoS general stress-response (modified from Figure 5 in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000208#pgen.1000208-Galhardo1" target="_blank">[2]</a>). …”

Examples demonstrating instances where the minimum number of mt protein-coding (PC) genes is either apparent or ambiguous. by Justin C. Havird (507301)

“…In these cases, the minimum number of genes that statistically recreated the “supergene” topology was chosen (e.g., a single gene, NAD5, for Haplorrhini). This alternative trend was atypical of the data (6.5% and 7.0% of lineages when utilizing amino acid and nucleotide data, respectively). …”

Endogenous BDNF and TrkB levels in retina and SC at various time points after ONC. by Eline Dekeyster (825249)

“…<p>(A) In the retina, the total BDNF levels, analyzed via ELISA, rise upon ONC, reaching a peak at 3 to 5 d, attenuating afterwards. …”

Smooth muscle differentiation and Notch target genes are down regulated in Notch2 and Notch2/Notch3 double mutants. by Qingqing Wang (141110)

“…Notch signaling target gene Heyl shows a robust decrease at E10.5 and E11.5 in the <i>Notch2^−/− (N2^−/−;N3^+/+)</i> and <i>Notch2^−/−;Notch3^−/− (N2^−/−;N3^−/−)</i> yolk sacs, while Hey2 shows a slight decrease and Hes1 expression is unaffected in the mutant genotypes. …”

Effect of RNAi depletion of selected hits on lipid droplet formation and TOR pathway activation. by Vangelis Kondylis (229490)

“…Red and blue columns indicate proteins whose depletion leads to a significant decrease or increase in the number of lipid droplets (marked with double asterisk; p<0.05). …”

Data_Sheet_1_Breeding With Major and Minor Genes: Genomic Selection for Quantitative Disease Resistance.docx by Lance F. Merrick (11240163)

“…There was also a statistical increase in the accuracy using the major markers in the validation sets as the mean accuracy decreased. …”

Ambient oxygen promotes chemical skin carcinogenesis. by Ho Joong Sung (221317)

“…<p><b>A.</b> Decreased skin papilloma formation using the two-stage chemical skin carcinogenesis model in 10% compared to 21% ambient oxygen. …”

Cognitive effects of the progressive exercise test in electricians wearing personal protective equipment by Leonardo Gomes Martins Coelho (5890073)

“…MAL was significantly higher after exercise in all situations: increasing frequency - 36.5 (5.1) Hz vs. 39.5 (2.7) Hz; decreasing frequency-36.0 (5.2) Hz vs. 39.0 (3.88) Hz; and general frequency 36.2 (4.9) Hz vs. 39.2 (3.1) Hz. …”

Tau knockout prevents sensitivity to Kainic acid–mediated stress in AICD-Tg mice. by Kaushik Ghosal (244754)

“…C. Mean seizure severity scores showed a significant rescue of seizure severity by Tau-/- in AICD animals. n = 4–5 mice per group (A-C). …”

Body Surface Potential Mapping during Ventricular Depolarization in Rats after Acute Exhaustive Exercise by Alexey G. Ivonin (13778765)

“…Also, compared with Pre-Ex, an increase in the amplitude of negative BSPM extremum at the R-wave peak on the ECG in lead II (RII-peak) and a decrease in the amplitude of negative BSPM extremum at 3 and 4 ms after RII-peak were showed at Post-Ex 5. …”

SC-1 Inhibited RSK2 Kinase Activity <i>in vitro</i> and an RSK2 Inhibitor Increased Colony Formation. by Susan D. Mertins (380936)

“…<p>COLO 205 tumor cell line was treated with SL0101 (1.25 µM) and SC-1 (0.1 µM) for 24 hrs prior to soft agar cloning, lysate preparation, and immunoblotting. A. SC-1 inhibited RSK2 N-terminal domain <i>in vitro</i> kinase activity with an EC₅₀ of 2.5±1.8 µM (mean±SD, n = 5) but not in other like assays for Aurora kinase B, CHK1, or CHK2 kinases. …”

Stimulation of Type III Nrg1 signaling enhances response to capsaicin in WT sensory axons. by Sarah E. Canetta (46254)

“…The maximum percent change in intracellular calcium ([(F−F₀)/F₀]*100) in response to capsaicin decreased between the 4^th and 5^th capsaicin applications under control conditions (left), but increased when Type III Nrg1 signaling was stimulated by sErbB4-ECD application during that interval (right). …”

Table_1_Postoperative myopic shift and visual acuity rehabilitation in patients with bilateral congenital cataracts.DOCX by Duoru Lin (4037966)

“…The postoperative mean SEs at each follow-up in the five groups were linearly fitted with a mean R² = 0.93 ± 0.03, which showed a downtrend of SE with age (linear regression). …”

DataSheet1_Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase.PDF by Lijun Ma (207865)

“…However, the spleen index decreased in the OXA and LBP + OXA groups (p < 0.05), possibly as a side effect of oxaliplatin. …”

Impact of BCG vaccination on the repertoire of human gamma/delta T cell receptors (ms data) by Mei Xia (14585347)

DataSheet1_Biomass burning-agriculture coupling in the Orinoco savannas—Particulate matter emission scenarios.PDF by Rodrigo Jimenez (10999161)