PIAS1 inhibits the ability of TGFβto suppress E-cadherin promoter activity. by Stuart J. Netherton (152258)

“…Aii) Each column is the mean (± SEM, n = 5) of the percent repression of luciferase activity by TGFβ relative to that of the basal (− TGFβ) of the corresponding transfection as shown in Ai (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013971#s4" target="_blank">MATERIALS and METHODS</a>). …”

Longitudinal MRI study of changes in BTB permeability and rCBV of brain metastases. by Heling Zhou (368949)

“…All the tumors except one (yellow arrowhead) still kept BTB intact at week 4. rCBV maps were created and rCBV values of the tumors were presented in the table (<b>B</b>). <b>C.</b> A total of 32 lesions in 5 animals were seen on both scans of weeks 3 and 4. rCBV of brain metastases (solid) was initially similar to that of contralateral normal brain (open; mean  = 1.05±0.05 (se) vs. 0.96±0.04), but decreased significantly (p<0.05) and became significantly lower as compared to their contralateral normal brain in the late scan (mean  = 0.88±0.06 vs. 1.00±0.06; p<0.05).…”

Ndrg2 mRNA is induced in wt mice by FXR agonists, reduced in livers of FXR^−/− versus wt mice and both FXR and NDRG2 mRNAs are reduced in human HCC versus normal liver.... by Ulrich Deuschle (129085)

“…Relative mRNA levels of Ndrg2, Shp, Cyp7a1 and Cyclophilin E were determined by RT-qPCR from wt (n = 5) and FXR^−/− (n = 5) mice as indicated. …”

Data_Sheet_1_Characteristics of Very High-Power, Short-Duration Radiofrequency Applications.pdf by Gábor Orbán (838800)

“…The very high-power, short-duration (vHPSD) radiofrequency (RF) ablation is a novel technology that favors resistive heating while decreasing the role of conductive heating. …”

<i>In vitro</i> validation of VH411 phage binding. by Marion David (366485)

“…In the present example, the cells were incubated with the anti-PVIII antibody (1/1000) detected with an allophycocyanine (APC) secondary antibody (1/800) (vertical axis) (B1, B3, B4, B5, B6) and with the anti-LDLR antibody (1/50) detected with a secondary FITC-labeled antibody (1/800) (horizontal axis) (B2, B3, B4, B5, B6). …”

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol by Peitao Wu (8811071)

Evaluation of ammonium fluoride for quantitative microwave-assisted extraction of silicon and boron from different solid samples by Lenka Husáková (776109)

“…The proposed method is recommended for fast and reliable preparation of samples with silicon content <8.2% (w/w). However, further decreasing the sample mass to 10 mg enabled the quantitative extraction of silicon from fly ashes at levels of 23% (w/w).…”

BMP signaling is required between 27 and 37 hpf for <i>runx2b</i> expression and head cartilage development. by Julia Dalcq (116948)

“…Dorsomorphin treatment of wt embryos and heat shock treatment of <i>(hsp70l:dnBmpr-GFP)w30</i> between 27 hpf and 37 hpf decreases <i>runx2b</i> expression in pharyngeal cartilage, but not in the cleithrum. …”

Neuronal living cells in hippocampus of wild type and CHOP−/− mice. by Chang-Mu Chen (315897)

“…<p>Tunicamycin (0.1 mg/ml) were intracerebroventricular injected in the hippocampus of wild type C57BL/6J (W; A) and CHOP−/− (B) mouse for 5–7 days. Neuronal cells were identified by immunofluorescence staining with Neu-N (green fluorescence). …”

Metabolites displaying the highest differences between TCF7L2 risk genotype carriers and controls. by Cornelia Then (81529)

“…Delta t35 (p = 2.7E-03) and t240 (p = 4.2E-03) of PC ae C40:5 are given as a representative example. Data are given as mean and standard error of the mean. * = p ≤ 0.05 after correction for multiple testing.…”

Effect of population size on the magnitude of distortion. by Alexander Coulton (8468724)

“…The dashed lines mark the 5% significance threshold for a chi-square test, whilst the dotted line marks a 1:1 segregation ratio. …”

Supplementary Material for: Efficacy and safety of transdermal medical cannabis (THC:CBD: CBN formula) to treat painful diabetic peripheral neuropathy of the lower extremities by Seevathee K. (20196534)

“…Results: The intervention group demonstrated statistically significant reductions in NPSI-T scores across all measured dimensions (p<0.001). Mean total NPSI-T scores decreased markedly from 25.60 to 5.57 in the treatment cohort, contrasting with minimal reduction from 25.24 to 22.85 in the placebo group. …”

MPA gap analysis results based upon alternate choices of datasets. by Casey C. O'Hara (3997529)

“…Scenario 2 updates the results using AquaMaps version 08/2015, showing very small changes despite the inclusion of an additional 5,545 species. Scenario 3, still using 2015 AquaMaps data, drops the presence threshold to zero, showing an expected decrease in gap species, but also a decrease in species with 5% or greater protected range. …”

Example simulation of the 2D Ising model. by Manfred Füllsack (4691716)

“…<p>Simulation of the 2D-Ising model with an external magnetic field H taken as critical parameter (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0259177#pone.0259177.e001" target="_blank">Eq 1</a>), on the x-axis, first increasing (H = -0.5 to 0.6, left half) and then decreasing (H = 0.6 to -0.5, right half). …”

Pace Versus Prediction: Is the Experience of the Runner Associated With Marathon Success? by Dan Gordon (2110918)

“…Significant differences observed between PT and FT for all EXP groups apart from EXP-5 (P= 0.0001). EXP-0 showed significant difference across all split times apart from 35-40 km (P=0.0001) with a decrease in normalised speed from 5km (109.0 ±7.6) –40km (89.9 ±7.4%). …”

LIS1 modulates cytoplasmic dynein activity in osteoclasts. by Shiqiao Ye (198070)

“…(B) Decreased LIS1 expression in osteoclasts causes dispersed Golgi apparatus (arrows in upper panels and inset 1, 3 and 5) and reduced transportation of CLIP170 to the periphery of osteoclasts. …”

Example of data processing for one participant and one task, Grooming. by Ryan R. Bailey (605367)

“…Vector magnitudes were smoothed using a 5-sample moving average, resulting in decreased amplitudes. …”

Supplementary file 1_Usage, anti-inflammatory effect and safety of adjunctive acupuncture for cerebral infarction: an Apriori algorithm-based data mining and meta-analysis.docx by Fangfei Yu (11906322)

“…Acupuncture with intermittent treatment (5–7 times per week), a combination of multiple points and multiple meridians (an average of 9.35 points in each prescription), typically lasting for 2–4 weeks, was commonly used for CI treatment. …”

12-HETE induces phosphorylation of VEGF-R2 and dephosphorylation of protein tyrosine phosphatase (PTP) SHP1 in REC. by Amira Othman (380131)

“…<p>Western blotting analysis (A) demonstrated significant increase in the level of pVEGF-R2 after 5 and 60 minutes from the beginning of treatment with 12-HETE. …”

Stronger evidentiary standards do not reduce the need to publish negative outcomes by Silas Boye Nissen (6815351)

“…Figure 6 Strengthening evidentiary requirements does not necessarily decrease canonization of false facts. In panel A, the false positive rate is α=0.05, the false negative rate is β=0.2, the original belief in the claim is q_0=0.5, and the evidentiary standards are symmetric τ_1=1-τ_0. …”