Involvement of clathrin-mediated endocytosis in NTBI uptake by PBMCs and HepG2 cells. by Joao Arezes (488491)

“…<p>(A–B) ⁵⁵Fe uptake by PBMCs and HepG2 cells in the presence of 0.45M of sucrose (A) or 80 µM of Dynasore (B) to inhibit clathrin-mediated endocytosis, after incubation with 5 µM of ⁵⁵Fe-citrate (5∶100) at 37°C (C–D) ¹²⁵I-Transferrin internalization in the presence of 0.45M of sucrose (C) or 80 µM of Dynasore (D). …”

Lyn regulated MCP-1 production by activating NF-κB. by Shibichakravarthy Kannan (265789)

“…Data were representative of two experiments with a group of 5 mice (infected and control). (D) Dominant negative Lyn construct transfection (DN = LynK275D) reduced NF-κB translocation in AECII as determined by a Luciferase NF-κB reporter assay. …”

Structural change induced in αS vs. NAA-αS by negatively charged vesicles. by Tim Bartels (606170)

“…Note the isobestic point (at 204 nm) indicative of a pure two state coil-helix transition. The arrow indicates the decrease in ellipticity at 222 nm as a consequence of helical folding. …”

Sema3C preserves type 2 alveolar epithelial cells (AEC2) viability in hyperoxia and promotes wound healing <i>in vitro</i>. by Arul Vadivel (424484)

“…Mean data of cell viability as assessed by measuring the mitochondrial-dependent reduction of colorless 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) shows that hyperoxia significantly decreases AEC2 viability as compared with room air exposed cells. …”

Phosphorylation of Cav-1 in ACT-treated CHO-K1 cells. by Kepa B. Uribe (229307)

“…In addition, incubation of cells with PP2 (5 nM) significantly decreased the degree of Cav-1 phosphorylation, being similar to control cells. …”

Anti-CD30 therapy reduces total HIV-1 DNA burden <i>ex vivo</i>. by Louise E. Hogan (4576501)

“…<p>Following <i>ex vivo</i> culture of PBMC in the presence of antiretroviral drugs (raltegravir, 3TC) and brentuximab vedotin for 5 days, we observed a significant reduction in the mean total cell-associated HIV-1 DNA from seven ART-suppressed individuals, despite no change in viable cell numbers. …”

Results of parameter exchange analysis. by Jing-yu Yu (181194)

“…One plus or minus sign corresponds to a 1.1 to 1.5 fold change in AUC; two plus or minus signs to a 1.5 to 2 fold change; and three plus or minus signs to a >5 fold change. …”

TREM-1 expression in B6 mice after treatment with FK506. by Weilan Huang (583018)

“…ELISA data (B) demonstrated that at 1 and 3 days post-infection, TREM-1 protein expression decreased after treatment with FK506, whereas no change was detected between the vehicle-treated group and the FK506-treated group at 5 days post-infection. …”

Ofd1, ciliary associated genes and Wnt signaling pathway genes expression in RCS rat retina. by Juan Wang (115708)

“…<p>RCS rats were sacrificed between 1 and 6 postnatal weeks. One-week-old (1w) RCS rats were used as the control. (A) <i>Ofd1</i> mRNA expression level increased between the 1st and 4th weeks, and decreased after the 4th week, as determined by qRT-PCR. …”

Stratification of genes that were differentially expressed in tissues determined to be infected (WNV (+)) or uninfected (WNV (−)) based on sensitive qRT-PCR detection of WNV RNA. by José Peña (95514)

Apocynin restores vasorelaxation of the diabetic aorta. by Sachin Gupte (363123)

“…</b> Diabetes did not alter the response to SNAP (a nitric oxide donor). Values are mean±SEM of 5 animals. * p<.05 compared to Wistar.…”

γδ T cells have similar TCR threshold but enhanced ERK1/2 phosphorylation comparing to αβ T cells. by Hsin-Yuan Cheng (414160)

“…Results were averaged from 5 mice, and shown in mean ± SEM. Lower: Log scaling of αCD3 concentration against % of maximum response was used to calculate EC₅₀. …”

Supplementary Material for: Idiopathic Vitreopapillary Traction: Case Report and Literature Review by Abdullah H. (18877477)

Genetic Polymorphism of Cytochrome P450 4F2, Vitamin E Level and Histological Response in Adults and Children with Nonalcoholic Fatty Liver Disease Who Participated in PIVENS and T... by Shaminie Athinarayanan (554806)

“…Among those receiving Vit E treatment, CYP4F2 V433M genotype was associated with significantly decreased plasma α-tocopherol levels at w48 (p = 0.003 for PIVENS and p = 0.026 for TONIC) but not at w96. …”

DMSO induces HLJ1 expression through AP-1. by Chi-Chung Wang (170486)

“…<p>(A) Western blotting analysis shows that the expressions of the components of AP-1 (JunD and JunB) are regulated by DMSO in a dose-dependent manner, whereas the expression of Fra-1 shows no change with DMSO treatment. …”

PF-04991532 increased hepatic futile cycling. by Derek M. Erion (568011)

“…PF-04991532 increased total hepatic substrate cycling due to increased substrate cycling between glucose and glucose-6-phosphate (n = 5–7/group) (<b>C</b>). The increased substrate cycling decreased hepatic ATP concentrations as assessed by NMR (n = 6/group) (<b>D</b>) which in turn increased hepatic pAMPK/AMPK ratio (<b>E</b>) (n = 5/group). …”

RNAi-based DtSER-1 deorphanization. by Mostafa Zamanian (315563)

“…<i>DtSER-1</i> knockdown corresponds to significantly decreased cAMP stimulation (∼32%) in response to 5-HT. …”

Supplementary Material for: Local recurrence in choroidal melanomas following Robotic assisted Radiosurgery (CyberKnife) by Schmelter V. (14069160)

“…Local recurrence occurred after 42.1 months post CyberKnife treatment (mean; range: 5 – 100 months). 14 out of 74 patients (18.9%) died during follow-up. …”

Effects of tiger17 on the MAPKs signal pathway. by Jing Tang (33607)

“…<p>(A) Raw 264.7 cells were treated with the indicated concentrations of tiger17 (2.5, 5, 10, 20 μg/ml) or vehicle; Western blotted for total or phospho-JNK, Erk or P38 was performed. β-Actin was used as the internal control. …”

Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx by Juanjuan Fang (413481)

“…Individuals whose DI-GM was 5 or above had a 34% decreased chance of sleep disorders compared to those with scores of 3 or less (OR: 0.66, 95% CI: 0.52–0.85), while DI-GM beneficial scores ≥6 reduced the risk by 35% compared to those with scores ≤1 (OR: 0.65, 95% CI: 0.49–0.85). …”