Effect of changes in the amount of positive reinforcement of R and T. by Guillermo E. Delmas (6169820)

“…<p>(<b>A</b>) The rats were pre-trained by pay-off matrix [<i>P</i>_<i>R</i> = 1, <i>P</i>_<i>T</i> = 3, <i>P</i>_<i>P</i> = 4, <i>P</i>_<i>S</i> = 8 and contrast ] (filled dots) and the cooperation was strongly affected by change of temptation payoff, decreasing when T payoff increased and matrix with changed to [<i>R</i> = 1, <i>T</i> = 5, <i>P</i> = 4, <i>S</i> = 8 and contrast ] (open circles). …”

PXDN mutant mice reveal impairment in bacterial clearance during acute lung infection. by Ruizheng Shi (5236607)

“…<p><b>(A)</b> Decrease of relative survival rates. PXDN-deficient and C57BL/6 wild-type mice were intratracheally instilled with 7 x 10⁶ of <i>P</i>. …”

Data_Sheet_1_Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of Campylobacter jejuni in chickens.pdf by Loïc Deblais (5620073)

“…</p>Results<p>Furthermore, we evaluated 177 SM hits (2.5 μg/mL and above) that increased the susceptibility to CuSO₄ for the inhibition of formate dehydrogenase (Fdh) activity, a Tat-dependent substrate. …”

DataSheet_1_Palmatine treats urticaria by reducing inflammation and increasing autophagy.docx by Tian Xiao (2601859)

“…Compared with the OVA group, the levels of immune and inflammatory factors were significantly reduced, neutrophil recruitment was alleviated, suggesting a reduced inflammatory response. The autophagy results showed that PAL further increased the expression of LC3, Beclin-1 and p-LKB1, p-AMPK, Atg5, Atg12 and Atg5-Atg12, while P62 and p-p70S6K1 expression decreased. …”

Inhibition of Uterine Sarcoma Cell Growth through Suppression of Endogenous Tyrosine Kinase B Signaling by Kenichi Makino (149077)

“…In <em>in vivo</em> studies in athymic nude mice bearing multidrug-resistant uterine sarcoma cell tumors, we demonstrate suppression of tumor growth by treatment with K252a, but not K252b, as reflected by decreased cell proliferation and increased levels of apoptosis and caspase-3/7 activities without obvious side effects. …”

Table_3_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

Table_2_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

Table_6_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

Table_7_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

Table_1_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

Table_4_Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.docx by Qing Song (77132)

“…The expression of GCN2 was significantly decreased (P < 0.05). A total of 106 differentially expressed miRNAs were identified. …”

ScFv 2LF dissociation rate constants with each LF variant, measured by Biacore experiments. by Philippe Thullier (320909)

“…<p>The five residues whose mutation to alanine resulted in a 3-fold, or larger, decrease of the dissociation constant are shown in bold.…”

Examining the Lateral Displacement of HL60 Cells Rolling on Asymmetric P-Selectin Patterns by Chia-Hua Lee (2239972)

“…We also used these findings to construct a Monte Carlo simulation for the prediction of rolling trajectories of HL60 cells on P-selectin-patterned substrates with a specified edge inclination angle. …”

Kinetics and Thermodynamics of Watson–Crick Base Pairing Driven DNA Origami Dimerization by John Zenk (652889)

“…We find that self-assembly reactions can be tuned by manipulating the interface architecture without suffering a loss in yield, even when yield is high, ∼75–80%. …”

Short and Long-Term Effects of the Angiotensin II Receptor Blocker Irbesartan on Intradialytic Central Hemodynamics: A Randomized Double-Blind Placebo-Controlled One-Year Intervent... by Christian Daugaard Peters (748219)

“…Mean start and mean end cardiac output, stroke volume, total peripheral resistance, heart rate, and mean arterial pressure were stable and similar in the two groups, whereas central blood volume increased slightly but similarly over time. …”

Supplementary Material for: First-in-human effects of PPT1 inhibition using the oral treatment with GNS561/ Ezurpimtrostat in patients with primary and secondary liver cancers by Harding J.J. (12088145)

“…Liver trough concentrations were much higher than in plasma a median time of 28 days of administration with a mean liver to plasma ratio of 9559 (Min 149-Max 25759), which is in accordance with rat preclinical data observed after repeated administration. …”

Table_1_Causality of particulate matter on cardiovascular diseases and cardiovascular biomarkers.pdf by Qiubo Wang (13168647)

“…To explore the causality of PM on CVDs and cardiovascular biomarkers, we conducted a Mendelian randomization (MR) analysis.…”

Gene Expression Pattern in Transmitochondrial Cytoplasmic Hybrid Cells Harboring Type 2 Diabetes-Associated Mitochondrial DNA Haplogroups by Seungwoo Hwang (214101)

“…Particularly, mtDNA haplogroup N9a is associated with a decreased risk of T2DM, whereas haplogroups D5 and F are associated with an increased risk. …”

Regulation of Gene Expression by PI3K in Mouse Growth Plate Chondrocytes by Veronica Ulici (76661)

“…Mouse E15.5 tibiae cultured with LY294002 (PI3K inhibitor) for 6 days showed decreased expression of factor XIIIa in the hypertrophic zone compared to control cultures.…”

Rhesus macaque CD4 alleles are universally defective for HIV-1 entry. by Cody J. Warren (563898)

“…Genotype information was used to phase SNPs using Phase 2.1 [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.ref081" target="_blank">81</a>,<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.ref082" target="_blank">82</a>] in DNAsp v5 [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.ref083" target="_blank">83</a>]. …”