Real-Time Cytotoxicity Assay for Rapid and Sensitive Detection of Ricin from Complex Matrices by Diana Pauly (170378)

“…Upon incubation with toxin the cell status and the cytotoxic effect were visualized using a characteristic cell index–time profile. For ricin, tested in concentrations of 0.06 ng/mL or above, a concentration-dependent decrease of cell index correlating with cytotoxicity was recorded between 3.5 h and 60 h. …”

DataSheet1_Real-time simulation of the transplanted tooth using model order reduction.DOCX by Pierre Lahoud (13931149)

“…The use of MOR reduced the time for delivering the root stresses by a mean 5.9 h. The biomechanical behavior of a transplanted tooth simulated by FE models was accurately captured with a significant decrease of computing time. …”

Data_Sheet_1_Impact of Alcohol Outlet Density on Reported Cases of Child Maltreatment in Japan: Fixed Effects Analysis.docx by Yuna Koyama (7462883)

“…Also, a negative association was observed between a change in the incidence of total child maltreatment by father and a change in alcohol outlet density (coefficient = −3.03, 95% confidence interval: −5.78, −0.28).…”

Hsp70-Hsp40 Chaperone Complex Functions in Controlling Polarized Growth by Repressing Hsf1-Driven Heat Stress-Associated Transcription by Aleksandar Vjestica (262087)

“…<div><p>How the molecular mechanisms of stress response are integrated at the cellular level remains obscure. Here we show that the cellular polarity machinery in the fission yeast <i>Schizosaccharomyces pombe</i> undergoes dynamic adaptation to thermal stress resulting in a period of decreased Cdc42 activity and altered, monopolar growth. …”

PPARγ activity negatively regulates neuronogenesis from NSCs. by Maude Rolland (769547)

“…Wild type uninfected NSC cultures (WT) stained with the same PPARγ antibody (green) are shown as a control (left). Scale bar: 50 μm. Bottom: In vitro neurogenesis assay showing significantly decreased number of HUC/D positive neurons generated from NSC-Pg (PPAR) stimulated by 1 μM rosiglitazone as compared to either untreated NSC-Pg or NSC-GFP (GFP) stimulated or not by rosiglitazone. …”

File S1 - Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex by Koji Yonekura (480516)

“…The representation scheme of molecules is the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078216#pone-0078216-g005" target="_blank">Fig. 5</a>. …”

The effects of EPA supplementation on the adhesive behaviour of neutrophils. by Samantha P. Tull (140603)

“…(C) Inhibition of neutrophil transmigration was evident at levels of EPA supplementation as low as 50 nM. Data are mean±SEM of five experiments. ANOVA showed significant effects of treatment (<i>p</i><0.05); *<i>p</i><0.05 compared to untreated control by Dunnett's test. …”

Supplementary Material for: Interim Evaluation of Germany’s Sugar Reduction Strategy for Soft Drinks: Commitments versus Actual Trends in Sugar Content and Sugar Sales from Soft Dr... by vonPhilipsborn P. (9232163)

“…Results: Between 2015-2021, the mean sales-weighted sugar content of soft drinks sold in Germany decreased by 2% from 5.3 to 5.2 g/100ml, falling short of an interim 9% reduction target and a 29% reduction observed in the United Kingdom over the same period. …”

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 7 by Yuri Efremov (8450409)

Pro-apoptotic effect of burns septic acute renal failure (ARF) group plasma on tubular cells and correlation with proteinuria by Filippo Mariano (11845)

“…Plasma from burns septic ARF group patients induced a dose-dependent decrease of tubular cell viability (XTT-based assay, n = 19, *p < 0.05 burns septic ARF group plasma 2.5%, 5% or 10% vs control healthy plasma). …”

Expression analyses of HSPG and integrin molecules as alternate receptors for fiber-modified Ads on AI-WAm cells. by Anton V. Borovjagin (342382)

“…<p>Expression of α_vβ3 and α_vβ5 integrins (<b>A</b> and <b>B</b>) and heparin sulfate proteoglycans (<b>C–E</b>) in AI-WAm cell population and control cells was analyzed by flow cytometry (<b>A</b>, <b>C</b>, <b>E</b>) and IHC staining (<b>B</b> and <b>D</b>). …”

The effects of intensified training on resting metabolic rate (RMR), body composition and performance in trained cyclists by Amy L. Woods (3839215)

“…Data were analysed using a linear mixed modeling approach.</p><p>Results</p><p>The intensified training period elicited significant decreases in RMR (F_(5,123.36) = 12.0947, p = <0.001), body mass (F_(2,19.242) = 4.3362, p = 0.03), fat mass (F_(2,20.35) = 56.2494, p = <0.001) and HRV (F_(2,22.608) = 6.5212, p = 0.005); all of which improved following a period of recovery. …”

Proteasome function is impaired by mutant or loss of PINK1. by Wencheng Liu (374270)

“…There was a statistically significant decrease of proteasome activity in the SH-SY5Y cells expressing L347P-PINK1 (23% reduction, n = 7, p = 0.018, paired student t test) or in SH-SY5Y cells expressing E417G-PINK1 (19.4% reduction, n = 8, p = 0.012, paired student t test) compared to cells expressing wild type PINK1. …”

Excitation-Contraction Coupling in Zebrafish Ventricular Myocardium Is Regulated by Trans-Sarcolemmal Ca²⁺ Influx and Sarcoplasmic Reticulum Ca²⁺ Release by Moritz Haustein (734263)

“…Surprisingly though, inhibition of the sarcoplasmic Ca²⁺-release decreased force development to 54±3% in ventricular (n=13, p<0.05) and to 52±8% in atrial myocardium (n=5, p<0.05) suggesting a substantial role of SR Ca²⁺-release in force generation. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

Regulation of CD36 mRNA expression by tumor necrosis factor (TNF)α and adalimumab by Jean Frédéric Boyer (32017)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…(D) AGS and GES-1 cells were pretreated with or without TAK-242 (1 uM) or SN50 (50 ug/ml) for 1 h prior to <i>H.pylori</i> infection. …”

FA and glucose oxidations in SCD1-overexpressed cardiac myocytes. by Hiroki Matsui (330019)

“…Each sample was counted in a scintillation counter (cpm) and data are shown as the mean ± SD. **P<0.01 vs. Ad-LacZ in each PA concentration. …”

IBM of growth: The effective carrying capacity 〈<i>N</i>〉 depends on the frequency of system updates. by Natalie Tkachenko (3937883)

“…The carrying capacity is <i>K</i> = 50. 50 realizations are performed for each set of parameters as indicated in the image. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”