Table_6_RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.xlsx by Yibin Yang (262311)

“…However, the toxicological mechanisms of Del on channel catfish remain unclear. In the present study, we exposed channel catfish to 0, 0.5, and 5 μg/L Del for 6 h, and analyzed the changes in histopathology, trunk kidney transcriptome, and intestinal microbiota composition. …”

Table_7_RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.xls by Yibin Yang (262311)

“…However, the toxicological mechanisms of Del on channel catfish remain unclear. In the present study, we exposed channel catfish to 0, 0.5, and 5 μg/L Del for 6 h, and analyzed the changes in histopathology, trunk kidney transcriptome, and intestinal microbiota composition. …”

Linagliptin does not increase catalase and MnSOD mRNA but trends to increase catalase protein level while significantly enhancing MnSOD protein level in G6PD^- mouse kidn... by Netanya Y. Spencer (5488931)

HeLa (Cilengitide treatment or MBCD treatment) PREM membrane images supporting "The structure and spontaneous curvature of clathrin lattices at the plasma membrane" by Kem Sochacki (10280270)

“…<br><div><br></div><div>HeLa cells were treated with drugs to remove cholesterol (methyl-β-cyclodextrin) or block the binding of aVB5 integrin (Cilengitide). Removing cholesterol caused an increase in flat clathrin while blocking integrins caused a decrease in flat clathrin. …”

Cx26 immunostaining and quantitative analysis in the neuromuscular compartment of normal and diverticular disease human colon. by Letizia Mattii (302997)

“…At higher magnification (C–F), SMCs show a punctuated immunoreactivity, which is localized at the membrane (arrows), cytoplasmic (asterisks), paranuclear and nuclear (arrowheads) levels; scale bars: 50 µm. (G) Image analysis of Cx26 expression. Each column represents the PPP mean ± SD (9</p>…”

The IgE repertoire is closely related to the IgG1 repertoire. by Adriana Turqueti-Neves (820798)

“…(D) Morisita-Horn indices show the relatedness (0 = unrelated; 1 = identical) between 1,000 randomly selected CDR3 sequences of the IgE and IgG1 repertoires or IgE and IgM repertoires (mean + standard deviation [SD], <i>n</i> = 3). (E) Mean frequency + SD of silent (blue) and nonsilent (red) mutations in V_H segments of IgG1 and IgE. …”

From Food to Offspring Down: Tissue-Specific Discrimination and Turn-Over of Stable Isotopes in Herbivorous Waterbirds and Other Avian Foraging Guilds by Steffen Hahn (185584)

“…Comparing these results with published data from other species we found no effect of foraging guild on discrimination factors for carbon but a significant foraging-guild effect for nitrogen discrimination factors.…”

Data_Sheet_1_Heterozygous Recurrent Mutations Inducing Dysfunction of ROR2 Gene in Patients With Short Stature.docx by Baoheng Gui (10645124)

“…The mRNA expression of downstream signaling molecules of the Wnt5a–ROR2 pathway was also examined.</p>Results<p>We identified 12 mutations in ROR2 in 21 patients, including 10 missense, one nonsense, and one frameshift. …”

Deletion of miR132/212 influences synaptic transmission and plasticity in the neocortex. by Judit Remenyi (178669)

“…Scale bar measures 20 ms and 5 pA. C) Superimposition of corresponding amplitude distributions of mEPSCs recorded in the fl/fl neuron (black) and miR-132/212 KO (grey) neuron. …”

Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport by Shanthie Thamotharan (3992894)

“…Finally to establish functional significance we performed dual-luciferase reporter assays with 3’-insertion of <i>miR-10b</i> alone and observed a ~10% reduction in the 5’-luciferase activity versus the control. …”

<i>In cellulo</i> Evaluation of Phototransformation Quantum Yields in Fluorescent Proteins Used As Markers for Single-Molecule Localization Microscopy by Sergiy Avilov (575857)

“…To this aim, we developed a data processing strategy based on the clustering optimization procedure proposed by Lee et al (PNAS 109, 17436–17441, 2012). …”

Functional connectivity revealed by rsfcMRI. by Corinna M. Bauer (3854026)

Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function by Jonathan J. Cherry (501180)

Changes in connectivity strength and network metrics during resting state and task periods. by Thomas P. K. Breckel (455915)

“…Attentionally resilient subjects (blue) began to recover during the post-task phase and showed a decrease in functional connectivity in the direction of the pre-task values, whereas attentionally impaired subjects (red) showed further increases in global connectivity strength until the end of the measurement (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074125#pone-0074125-g005" target="_blank">Figure 5</a> A). …”

Increased aerobic glycolysis in MADD fibroblasts and <i>xav</i> mutants. by Yuanquan Song (238595)

“…<p><b>A.</b> ECAR was measured in intact control and MADD Patient 1 fibroblasts under basal conditions, following the addition of the mitochondrial inhibitor oligomycin (0.5 µg/ml), in the presence of the uncoupler CICCP (3 µM) and following the addition of the complex I inhibitor rotenone (100 nM). …”

Vulnerability to high fat diet-induced obesity. by Alessandro Bartolomucci (165364)

“…At baseline, when mice were fed standard diet, all experimental groups showed a decrease in body weight, while controls (Con) showed a slight increase (F(3,23) = 3.2, p<0.05). …”

Cx43 immunostaining and quantitative analysis in the neuromuscular compartment of normal and diverticular disease human colon. by Letizia Mattii (302997)

“…At higher magnification (C–F), SMCs show a punctuated immunoreactivity, which is localized at the membrane (arrows), cytoplasmic (asterisks), paranuclear and nuclear (arrowheads) level; scale bars: 50 µm. (G) Image analysis of Cx43 expression. Each column represents the PPP mean ± SD (8</p>…”

Endometriosis Is Associated with Rare Copy Number Variants by Rakesh Chettier (73475)

“…Three CNV's passed a genome-wide P-value threshold of 9.3×10⁻⁴; a deletion at <i>SGCZ</i> on 8p22 (P = 7.3×10⁻⁴, OR = 8.5, Cl = 2.3–31.7), a deletion in <i>MALRD1</i> on 10p12.31 (P = 5.6×10⁻⁴, OR = 14.1, Cl = 2.7–90.9), and a deletion at 11q14.1 (P = 5.7×10⁻⁴, OR = 33.8, Cl = 3.3–1651). …”

Measurement of mitochondrial function in nasal fibroblasts with and without TGF-β1 or with and without PX-478 To investigate whether mitochondrial function are elevated by TGF-β1,... by Min-Sik Jo (14636809)

“…<p>Oxygen consumption rate (OCR) was significantly increased at 5 ng/ml TGF-β1 (S1A Fig). To determined whether PX-478 decrease mitochondrial function, PX-478 (20 nM) was pretreated for 1 hour, followed by TGF-β1 48 hours. …”

Modelling of the effects of En1 and En2 on hippocampal cells. by Asma Soltani (4356841)

“…In normal conditions (black lines), low levels of endogenous secreted En1 (from GABA cell for instance) could participate to dendritogenesis (1), spinogenesis (2) (insert), and mTOR signaling (3) in neighbor glutamatergic neurons. In a pathological context, such as autism (red lines), a rise of En2 expression and secretion would generate additional effects, i.e. the increase in dendritic complexity of GABA cells (4), a decrease of clustered PSD95 (5), and the mispairing of glutamatergic synapses (6) (insert). …”