Heatmaps of the top 536 differentially expressed genes (DEG) by calcitriol in CaSki cells with fold changes ranging from 1.5 to −1.5. by Euclides Avila (41023)

Image_5_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF by Guangjin Chen (1989892)

“…Notably, the downregulation of PLAU decreased the expression of TNFRSF12A. Moreover, knockdown TNFRSF12A also inhibits cell proliferation and migration. …”

A savanna response to precipitation intensity - Fig 3 by Ryan S. Berry (3913207)

Azole Assisted C–H Bond Activation Promoted by an Osmium-Polyhydride: Discerning between N and NH by Beatriz Eguillor (1326744)

“…The latter is the result of a N-assisted <i>ortho</i>-C–H bond activation of the phenyl group promoted by 0.5 equiv of <b>1</b> and the N–H bond activation promoted by the remaining 0.5 equiv of hexahydride <b>1</b> along with the agostic coordination of the remaining <i>ortho</i>-C–H bond to the metal center of the unsaturated fragment OsH­(η ²-H₂)­(PⁱPr₃)₂. …”

Azole Assisted C–H Bond Activation Promoted by an Osmium-Polyhydride: Discerning between N and NH by Beatriz Eguillor (1326744)

“…The latter is the result of a N-assisted <i>ortho</i>-C–H bond activation of the phenyl group promoted by 0.5 equiv of <b>1</b> and the N–H bond activation promoted by the remaining 0.5 equiv of hexahydride <b>1</b> along with the agostic coordination of the remaining <i>ortho</i>-C–H bond to the metal center of the unsaturated fragment OsH­(η ²-H₂)­(PⁱPr₃)₂. …”

Erg251 is the major methyl sterol oxidase controlling drug susceptibility compared to its paralog Erg25. by Xin Zhou (54275)

A Randomized Clinical Trial to Evaluate Two Doses of an Intra-Articular Injection of LMWF-5A in Adults with Pain Due to Osteoarthritis of the Knee by David Bar-Or (518741)

“…LMWF-5A resulted in a significant decrease in pain at 12 weeks compared to vehicle control (−0.93 vs −0.72; estimated difference from control: −0.25, p = 0.004); an injection volume effect was not observed (p = 0.64). …”

Sensitivity of COPD classification using 1, 2, 3, and 4 year LBPs compared to 5-year LBP among patients with 5 years continuous enrollment (The reference LBP). by Eman Metwally (19928829)

Hill function parameters used in Eqs (4), (5) and (6). by Ilaria Demori (19105915)

SARS-CoV-2 inhibition by MAP30 and Momordin. by Norman R. Watts (1964959)

Impact of group 1 and group 2 drugs on hyperglycemia based on HbA1c levels before and after 3 months of administration. by Nadia Gul (249538)

Microgliosis and astrogliosis are not exacerbated by homozygous GBA1 D409V mutation in the striatum and substantia nigra. by Nicole K. Polinski (10947787)

Bovine Serum Albumin Adsorption at a Silica Surface Explored by Simulation and Experiment by Karina Kubiak-Ossowska (1271013)

“…Molecular details of BSA adsorption on a silica surface are revealed by fully atomistic molecular dynamics (MD) simulations (with a 0.5 μs trajectory), supported by dynamic light scattering (DLS), zeta potential, multiparametric surface plasmon resonance (MP-SPR), and contact angle experiments. …”

A) Surface water, B) precipitation, and C) mean annual temperature (MAT) trends, 2000–2019, smoothed by loess curves (degree = 2, span = 0.5) for better visualization of patterns.... by Danielle L. Rupp (12889935)

CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

Schematic diagram of time stamp synchronization between LIDAR and camera in a multi-sensor system. by Hongliang Zou (20707270)

Simulated Sea Level Rise in Coastal Peat Soils Stimulates Mercury Methylation by Bryce A. Cook (19433235)

“…Here, the effect of sea level rise on MeHg formation in the Florida Everglades was evaluated by incubating peat cores from a freshwater wetland for 0–20 days in the laboratory at five salinity conditions (0.16–6.0 parts-per-thousand; 0.20–454 mg L^–1 sulfate (SO₄^2–)) to simulate the onset of sea level rise within coastal margins. …”

Definitions of the features selected [50]. by Yu Zhang (12946)

Data_Sheet_1_5-HT1A Receptor Agonist Promotes Retinal Ganglion Cell Function by Inhibiting OFF-Type Presynaptic Glutamatergic Activity in a Chronic Glaucoma Model.docx by Xujiao Zhou (6661499)

“…However, the roles of excitatory amino acids and their interactions with the 5-HT1A receptor in glaucoma remain unknown. Here, we found that ocular hypertension increased glutamine synthetase (GS) and excitatory amino acid transporter 2 (EAAT2) expression in rat retinas. …”

DataSheet1_Gestational intermittent hypoxia reduces mandibular growth with decreased Sox9 expression and increased Hif1a expression in male offspring rats.docx by Takumi Suzuki (12687350)