Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> leaves on A) ATP, B) p-mTOR, C) beclin-1, and D) p-AMPK levels. by Fatma A. Moharram (9276104)

Effect of different doses (mg/Kg) of the defatted extract (DE) of the leaves of <i>S. malaccense</i> and <i>S. samarangense</i> on serum ALT and AST levels. Data represented as mea... by Fatma A. Moharram (9276104)

Total ion chromatogram (TIC) obtained from HPLC-MS of the defatted aqueous methanol extract of <i>S. malaccense</i> leaves in (A) positive and (B) negative ionization modes. by Fatma A. Moharram (9276104)

Total ion chromatogram (TIC) obtained from HPLC-MS of the defatted aqueous methanol extract of <i>S. samarangense</i> leaves in (A) positive and (B) negative ionization modes. by Fatma A. Moharram (9276104)

Activation of ERα with estrogen simultaneously increases PR expression and decreases Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Validation of a New Scoring Scale for Behavioral Assessment of L‑Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development by Simon Loiodice (4715610)

“…The rating scale was sensitive enough to highlight a dose-dependent amantadine-mediated decrease (about 2.2-fold) in LID score. …”

Administration of APB5, but not APA5, decreases the hyperplasia of alveolar type 2 epithelial cells induced by BLM. by Masami Kishi (6167105)

“…The administration of APB5 markedly decreased the hyperplasia of type 2 epithelial cells induced by BLM. …”

Decreased ratio of GSH/GSSG in <i>Slc1a1-</i>HET mice. by Parisa Afshari (4423141)

hMSC adjunctive therapy failed to decrease pulmonary inflammation or prevent ALI compared to antiviral therapy alone in experimental severe influenza. by Ilyse Darwish (446378)

“…<p>Eight-week old male C57Bl/6 mice infected with 425 EID₅₀ influenza A/PR/8 virus were administered 2.5 mg/kg oseltamivir in 100 ul ddH2O via gavage, 1×daily for 5 days, beginning day 2 P.I., with or without hMSC administration (5×10⁵ cells) on day 2 P.I. and sacrificed on day 7 P.I. …”

Identification of Gut Microbiota Biomarker Genera Distinguishing Wild and Captive Animals (A) Top 50 discriminative genera selected by random forest classifier, ranked by mean decrease accuracy. by Lin Xu (94491)

DOM assembly monitored with temperature and pH reveals that, as either pH decreases or temperature increases, microgel equilibrium size and assembly rates decrease at a non-linear... by Chi-Shuo Chen (234719)

Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome by Heon Shin (4559110)

“…Surprisingly, in ALDH6A1-O/E cells, NO was decreased nearly 50% but ROS was increased at a similar level, while the former was restored by treatment with <i>S</i>-nitroso-<i>N</i>-acetyl-penicillamine. …”

Attenuation of spheroid size decrease or MUC5AC increase by hit compounds. by Pranjali Beri (14945400)

“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”

Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice. by Katherine R. Sadleir (12035242)

“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”

Co-ordinated spatial propagation of blood plasma clotting and fibrinolytic fronts - Fig 5 by Ansar S. Zhalyalov (4233721)

The effects of GM-CSF on DMN-induced histopathological changes. by Mrigendra Bir Karmacharya (13607415)

Enrichment of Phosphatidylethanolamine in Viral Replication Compartments via Co-opting the Endosomal Rab5 Small GTPase by a Positive-Strand RNA Virus by Kai Xu (122914)

“…Deletion of Rab5 orthologs in a yeast model host or expression of dominant negative mutants of plant Rab5 greatly decreases TBSV replication and prevents the redistribution of PE to the sites of viral replication. …”

Diverse stress conditions trigger a rapid and dramatic decrease in miR-520b-3p and a corresponding increase in ATF5 mRNA over time in HeLa cells. by Kari A. Gaither (9046190)

A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice by Hiroaki Yashiro (2231686)

“…Here, we demonstrate reduced insulin resistance and the anti-obesity effect of a D5D selective inhibitor (compound-326), an orally active small-molecule, in a high-fat diet-induced obese (DIO) mouse model. …”

Circadian Genes, <i>xBmal1</i> and <i>xNocturnin</i>, Modulate the Timing and Differentiation of Somites in <i>Xenopus laevis</i> by Kristen L. Curran (95520)

“…We observed opposing effects on somite size. Depletion of xBMAL1 or xNOCTURNIN caused a statistically significant decrease in somite area (quantified using NIH ImageJ; p<0.002), while overexpression of these proteins caused a significant dose dependent increase in somite area (p<0.02; p<0.001, respectively). …”