Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Decreased expression of 5-HT_2A receptors but not of PSD-95 in spinal cord of carrageenan-injected rats. by Anne-Sophie Wattiez (460341)

Fig 5 - by Rabeya Binta Alam (17364707)

Inhibition of the TrkA signaling protected mice from lethal A/PR8 infection. by Vikram Verma (13822961)

EMBS-treated cells undergo apoptosis correlated with decreased cell viability, metabolic activity and mitochondrial membrane potential. by Michelle Helen Visagie (3927308)

S5 Table - by Mohamad Karaky (8910497)

Subjects:

Effect of CXB and DMC combinations on P-glycoprotein protein content and activity of P-glycoprotein in HeLa (A) and SiHa cells (B). by Diana Xochiquetzal Robledo-Cadena (5265959)

Effect of the stabilized MetA on the persister cell frequency under acidic conditions. by Elena A. Mordukhova (646403)

Shiga toxin expression in O157 following treatment with hGRNL, bNK2A, and pNKL peptides. by Erika N. Biernbaum (12647386)

Effect of thalidomide on expression and cellular localization of CUL5 in control RAMEC and RAMEC transfected with ^S730ACUL5. by Bryan Kunkler (5204327)

Annexin A2 accumulates in the nucleus and decreases in the cytoplasm in response to genotoxic agents. by Patricia A. Madureira (114480)

Effect of L-methionine on the frequency of persisters at different temperatures. by Elena A. Mordukhova (646403)

Mutation of <i>talB</i> in BAI3 results in a decrease of virulence partially complemented by the induction of <i>OsERF#123</i>. by Tuan T. Tran (5335004)

Inner medullary expression of the V2 vasopressin receptor. by Sophie Constantin Lütken (689916)

Subjects:

Photostimulation of DRN 5-HT neurons <i>in vivo</i>. by Guillaume P. Dugué (620333)

Physiologic values. by Hiroki Iwata (2434012)

“…The serum syndecan-1 concentration, a glycocalyx component, in the 4% hydrogen group (5.7 ± 4.4 pg/mL) was lower than in the control (19.5 ± 6.6 pg/mL) and 2% hydrogen (19.8 ± 5.0 pg/mL) groups (<i>P</i> < 0.001 for each), but it was not significantly different from the sham group (6.2 ± 4.0 pg/mL, <i>P</i> = 0.999). …”

Hemolytic activities of hGRNL, bNK2A, and pNKL peptides on cattle red blood cells (RBCs). by Erika N. Biernbaum (12647386)

Caspase-1 activation during <i>Eh-</i>macrophage contact degrades cullin-1/5. by Attinder Chadha (11414273)

Subjects:

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<i>fapR</i> mRNA levels were quantified by RT-qPCR using 16S rRNA as reference gene on total RNAs extracted from <i>wt</i> strain (PR01), <i>ΔcshA</i> strain (PR01-ΔcshA), and suppressor strains <i>ΔcshA/accC</i>^<i>M385V</i> (C51), <i>ΔcshA/accC</i>^<i>T183I</i> (sup30), <i>ΔcshA/accD</i>^<i>F253V</i> (sup17), <i>ΔcshA/accD</i>^<i>A164V</i> (sup16), <i>ΔcshA/birA</i>^{<i>D320F-FsX28</i>} (C58), <i>ΔcshA/birA</i>^{<i>R280stop</i>} (sup1) and <i>ΔcshA/bioY</i>^{<i>P123R-FsX1</i>} (C66), all at exponential growth phase in MH medium at 25°C. n = 5 for <i>ΔcshA</i>, <i>4 for wt</i> and 3 for all others. …”

LY5 does not inhibit growth of <i>ex vivo</i> pulmonary metastasis. by Peter Y. Yu (4281448)