Performance in reconstruction of detailed parameters. by Jiawen Chang (12864896)

“…<p><b>(A)</b> Ground truth features of Model A. The regional recurrent strength <i><i>w</i></i>_<i>i</i> is rescaled from empirical anatomical heterogeneity [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013612#pcbi.1013612.ref043" target="_blank">43</a>], while the external input <i><i>I</i></i>_<i>i</i> is set to decrease with hierarchy to be consistent with previous work [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013612#pcbi.1013612.ref036" target="_blank">36</a>]. …”

RanBP2 promotes the sumoylation and inhibits the ubiquitination of AGO1. by Qingtang Shen (200108)

“…Note that Ubc9 overexpression rescued RanGAP1-sumoylation in RanBP2-dE3 cells and decreased the amount of ubiquitinated FH-AGO1. See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009378#pgen.1009378.s010" target="_blank">S10F Fig</a> for the quantification of (Ub)n-FH-AGO1 levels. …”

Data_Sheet_1_Changes in the Thermal and Hydrometeorological Forest Growth Climate During 1948–2017 in Northern Germany.docx by Banzragch Bat-Enerel (12547519)

“…Here, we analyze T, P, CWB, and SPEI trends separately for all growing season months (April-September) during the 1948–1982 (before the recent warming) and 1983–2017 periods (after the onset of warming) in their spatial variation across the North German Lowlands based on a dense climate station network. While trends in thermal and hydrometeorological variables were weak from 1948 to 1982, we find a significant decrease in April precipitation and increase in July precipitation from 1983 to 2017 throughout much of the study region, while June precipitation has decreased locally by 10 mm or more (or up to 20%). …”

Combined Enzymatic and Physical Deinking Methodology for Efficient Eco-Friendly Recycling of Old Newsprint by Antar Puneet Virk (446380)

“…Surface appeared more fibrillar along with changes in surface functional groups. A combination of physical and enzymatic processes (S-MW-XL) for deinking further improved brightness (28.8%) and decreased ERIC (73.9%) substantially.…”

EPO down-regulates proliferation of MOG-specific T cells and suppresses T cell cytokine production. by RuiRong Yuan (43904)

“…Supernatants were collected from the cultured MOG-T cells for cytokine profile analysis and the remaining cells were quantified for number of CD8 and MOG_44–54/H-2Db dimer double binding cells after exposure to EPO or control treatment. EPO induced a marked decrease in pro-inflammatory cytokine production (black bars) when compared to controls (white bars). …”

TSS-targeted siRNA abolishes the heparanase expression in cancer cells. by Guosong Jiang (182435)

“…<p><b>A</b>, scheme of siRNAs targeting TSS (locating at 101 bp upstream of the translation start site), upstream promoter and encoding regions of heparanase, including siH1 (−174/−155 bp), siH2 (−134/−115 bp), siH3 (−9/+10 bp) and siH4 (+1496/+1515 bp). …”

Fig 1 - by M. Latorre (8840546)

“…<p>Fully developed, mechanobiologically equilibrated, axisymmetric dilatations of an initially cylindrical aortic segment caused by a mild (first column) or severe (second column) localized (via the respective parameter <i>ϑ</i>_{<i>central</i>} in Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008273#pcbi.1008273.e024" target="_blank">9</a>)) loss of elastic fiber integrity (first row, parameter <i>c</i>^<i>e</i>, mild 32% and severe 62% reduction), decrease in collagen cross-linking (second row, parameter , mild 9%, severe 23% reduction), loss of smooth muscle contractility (third row, parameter <i>T</i>_<i>max</i>, mild 60%, severe 100% reduction), compromised mechanosensing (fourth row, parameter <i>δ</i>, mild 7.5%, severe 18.5%, absolute), or compromised mechanoregulation (fifth row, parameter <i>G</i>^<i>c</i>, mild 0.4%, severe 1.2%, relative change), with the risk factors of hypertension (third column, 50% increase in blood pressure) and aortic aging (fourth column, uniform 30% loss of elastic fiber integrity) superimposed on the mild insults. …”

Impact of intravenous iron or exogenous erythropoietin on hemoglobin mass, exercise performance, and acute mountain sickness during altitude acclimatization_ Supplemental Tables.do... by Karleigh Bradbury (21722654)

“…<p dir="ltr">Chronic exposure to high altitude leads to increases in hemoglobin mass (Hbmass), which may lead to improved exercise performance and decreased acute mountain sickness (AMS) symptoms. We evaluated the influence of intravenous iron or erythropoietin (EPO) treatment on Hbmass, exercise performance, and AMS during a 14-day exposure to 3094 m. …”

Patterns of Gene Expression in Peripheral Blood Mononuclear Cells and Outcomes from Patients with Sepsis Secondary to Community Acquired Pneumonia by Patricia Severino (5658397)

“…Microarray-based expression profiling is a powerful approach for the investigation of complex clinical conditions such as sepsis. In this study, we investigate whole-genome expression profiles in mononuclear cells from survivors (n = 5) and non-survivors (n = 5) of sepsis. …”

Osteoporosis and hearing loss: findings from the Korea National Health and Nutrition Examination Survey 2009-2011 by Jun-Il Yoo (6317567)

“…In osteoporosis, the mass of the ossicles will be decreased, affecting the bone density of the cochlea, and interfering with the sound transmission to the cochlea. …”

Moist-Retaining, Self-Recoverable, Bioadhesive, and Transparent in Situ Forming Hydrogels To Accelerate Wound Healing by Jun Li (6494)

“…The physicochemical properties of M-CMCS/O-HES hydrogels with various ratios were investigated, and M-CMCS/O-HES hydrogel with a volume ratio of 5:5 exhibited appropriate gelation time, notable water-retaining capacity, self-recoverable conformal deformation, suitable biodegradability, and good biocompatibility for wound-healing application. …”

DataSheet_1_Effects of habitat usage on hypoxia avoidance behavior and exposure in reef-dependent marine coastal species.docx by Haolin Yu (14672189)

“…Relatively little is known about the effects of hypoxia on organisms that use complex habitat arrangements and how the presence of highly preferred AR habitat can affect the exposure of organisms to low dissolved oxygen (DO). We performed two laboratory experiments that used video recording of behavioral movement to explore 1) habitat usage and staying duration of individuals continuously exposed to 3, 5, and 7 mg/L dissolved oxygen (DO) in a complex of multiple preferred and avoided habitat types, and 2) the impact of ARs on exposure to different DO concentrations under a series of two-way replicated choice experiments with or without AR placement on the low-oxygen side. …”

Assessment of Health-Related Quality of Life in alcoholic hepatotoxic patients by Deepjyoti saikia (14428197)

Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes-3 by Vassilios Sotiropoulos (96257)

“…</p><p></p>cules (WT/w 2000 Tc, green line) or 5000 molecules (WT/w 5000 Tc, red line) of Tc are added into the medium at time 2 × 10sec, using wild-type kinetics. (B) Average number of GFP molecules when 2000 molecules of Tc are added into the medium at time 2 × 10sec, using wild-type kinetics (WT/w 2000 Tc, blue line), a 10 fold (Des 2.1/w 2000 Tc, green line) and a 50 fold (Des 2.2/w 2000 Tc, red line) increase in the dissociation constant of both TetR and induced Tet-ON from of the gene encoding Tet-ON. …”

The changes in the expression of downstream molecules of each compound. by Yuya Fujii (7326947)

“…Axin2, downstream molecule of Wnt/β-catenin pathway; LTBP1, downstream molecule of TGF-β pathway; Id, downstream molecule of BMP pathway; DLL1, downstream molecule of the Notch pathway (n = 5). All data are presented as the mean ± SEM. *p < 0.05, as per Wilcoxon rank sum test.…”

Data_Sheet_1_Functional ultrasound detects frequency-specific acute and delayed S-ketamine effects in the healthy mouse brain.docx by Tudor M. Ionescu (15534440)

“…These changes persisted to a weaker extent after 1 day and at this timepoint they were accompanied by decreases in the other five bands as well. After 9 days, the decreases in the 0.75–1.25 Hz band were maintained, however no changes between cohorts could be detected in any other bands.…”

<i>Varroa destructor</i> occurrence is linked to regional, temporal and climatic variables. by Alison McAfee (1392388)

“…C) Occurrence probabilities significantly decrease with higher wind speeds, but the effect is reduced when temperatures are warm (wind-by-temperature interaction: χ² = 4.8, df = 1, p = 0.029; see also <b><a href="/article/info:doi/10.1371/journal.pclm.0000485#pclm.0000485.s008" target="_blank">S2 Fig</a></b>). …”

Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes by Guruprasad Ananda (599807)

“…Centrally located interruptions lowered mutability dramatically, by two to three orders of magnitude. Using a biochemical approach, we tested directly whether the mutability of a specific iMS is lower because of decreased DNA polymerase strand slippage errors. …”

Impact of water stress on hypocotyl length, width and volume in dark-grown seedlings. by Nils Kalbfuß (14248277)

“…Scale bars = 1mm. See related <b>Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010541#pgen.1010541.g001" target="_blank">1</a></b> and <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010541#pgen.1010541.s003" target="_blank">S3</a></b>.…”

An in vivo murine calvarial model of particle-induced osteolysis demonstrates Cobalt-alloy debris co-challenge with TLR4 induces osteolysis but not more than Cobalt alloy alone. by Lauryn Samelko (424639)

“…(A) Representative images (n = 1/5) and (B) Graphical representation of the percentage decrease in bone thickness relative to sham controls (average of n = 5 per group). …”