Seizure-induced alterations in NKCC1 and KCC2 protein levels. by Ryan T. Cleary (387997)

“…NKCC1 increased transiently at 24 hr post-HS (n = 8, 138±10.5% control, <i>p</i> = 0.005) in cortex, but showed no significant change in hippocampus. …”

Chromatin Remodeling, Cell Proliferation and Cell Death in Valproic Acid-Treated HeLa Cells by Marina Barreto Felisbino (191449)

“…</p> <h3>Methodology/Principal Findings</h3><p>Image analysis was performed by scanning microspectrophotometry for cells cultivated for 24 h, treated with 0.05, 0.5 or 1.0 mM VPA for 1–24 h, and subjected to the Feulgen reaction. …”

General scheme of dormant cells production and viability assessment of <i>M</i>. <i>tuberculosis</i> H37Rv cells subjected to further proteomic analysis. by Vadim Nikitushkin (4569475)

“…<p>A) The outline of the model of gradual acidification of the bacterial culture in the post-stationary phase used in the current study [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0269847#pone.0269847.ref013" target="_blank">13</a>]. …”

Table_1_Efficacy and tolerability of full spectrum hemp oil in dogs living with pain in common household settings.DOCX by Chinmayee Panda (19111154)

“…The intervention was positively associated with a decrease in pain scores (−46.2%, p = 0.0016), increased ability to walk up and down the stairs (10.6–14.7%, p < 0.05), and improved daily activity (25.9%, p = 0.0038). …”

Mtb transmission model schematic. by Joshua Havumaki (607091)

“…The parameters are as follows, <i>μ</i> is the mortality rate, λ is the force of infection (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0293519#pone.0293519.e001" target="_blank">Eq 1</a> for details) which is modulated by <i>ω</i> to account for partial immunity among previously or currently infected individuals, <i>ϵ</i> is the rate of progression from early latent to active TB (rates of progression decrease as time since infection increases as represented in the <i>EL</i> sub-states panel), <i>τ</i> is the rate of progression from late latent to active TB, <i>κ</i> is the active TB mortality rate, <i>γ</i> is the rate of spontaneous recovery from active TB, <i>ATB</i> <i>treat</i> is the treatment rate of individuals in active TB, and finally <i>txd</i> is the duration of treatment. …”

Burst stimulation. by Damian M. Herz (16007088)

“…<p><b>(A)</b> DBS bursts from example trials illustrating when stimulation bursts (black rectangles) were applied in the first 10 trials of patient 1, aligned to peak force. …”

<i>Hoxa13</i> expression in chicken limb buds. by Nayuta Yakushiji-Kaminatsui (6008795)

“…*<i>p</i> < 0.05; NS, <i>p</i> > 0.05, Welch two-sample <i>t</i> test. For both A and B, individual numerical values of RT-qPCR are given in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000004#pbio.3000004.s009" target="_blank">S1 Table</a>. …”

MNV replication results in gradual translational shut-off and hallmarks of eIF2α signaling activation in cell lines and primary cells. by Michèle Brocard (28457)

“…<p>Decrease protein synthesis in MNV-infected RAW264.7 cells (A and B) or primary murine BMDMs (D and E). …”

Data_Sheet_1_Different profiles of acute graft pyelonephritis among kidney recipients from standard or elderly donors.pdf by Rita Tarragoni (18550477)

“…Ureteral stenosis was the only risk factor associated with AGPN (OR 2.9 [95% CI, 1.6 to 5.2]). KTs with AGPN had a decreased allograft function at the first year (ΔeGFR 6 mL/min/1.73 m² [−2–15] in non-AGPN vs. −0.2 [−6.5–8.5] in AGPN, p < 0.001), with similar and negative profiles in KTs from standard or elderly donors. …”

<i>Mab21l2</i> is required for the formation of the septum transversum mesenchyme near hepatoblasts and for normal liver development. by Yohei Saito (180130)

“…<p>(A–D, G, H, M–P) <i>In situ</i> hybridizations of transverse paraffin sections of E8.5, E9.5 and E10.5 WT and <i>Mab21l2</i> mutant embryos, for the transcripts indicated. …”

Two-parameter bifurcation diagrams of the DA neuron and the HH neuron in <i>v</i>_nh/<i>v</i>_hh/<i>v</i>_mh and <i>I</i>_app planes. by Andrey Dovzhenok (311885)

“…<p>The hysteresis regions are shaded gray. A) Hysteresis is strong in the DA neuron. Parameters are from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042811#pone-0042811-t001" target="_blank">Table 1</a>. …”

P and D Modules Correspond to the Proliferation/Differentiation Switch by Kai Xia (54092)

“…Red and green colors indicate an increase and a decrease in the differentiated samples, respectively. …”

Model results. by Joeri B. G. van Wijngaarden (2936472)

“…From top to bottom: 100 neurons of the three thalamic nuclei TRN, NSP, SP plus the excitatory cortical population (CRX). A lesion was introduced after 10 seconds of real-time simulation time by deafferentating 30% of the cortical neurons, resulting in a loss of driving inputs for the thalamic neurons marked in grey. …”

Impact of liposomal bupivacaine and provider choice on opioid use and service outcomes in Medicare outpatient surgical patients by Allen Dobson (11229807)

“…For each 10% increase in LB use rate by a given provider, Part D opioid events by Day 30 decreased by 2.6 percentage points and by 2.1 percentage points by day 90 (<i>p</i> < .01). …”

The distribution of Tbr2+ mitoses shifts to the outer subventricular zone (oSVZ) during early stages of cortical development in macaque, but not in ferret or rat. by Verónica Martínez-Cerdeño (155789)

“…At P2, during neurogenesis of layer 2 neurons <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030178#pone.0030178-Noctor4" target="_blank">[19]</a>, 73% of Tbr2+ mitoses were still located in the iSVZ. …”

Alteration of the steady state equilibrium pupillary reflex response following pre-exposure with monochromatic lights. by Ludovic S. Mure (262696)

“…<p>(A) Representative responses of a subject during the 5 minutes of 480 nm monochromatic light (test stimulation, 1e12 photons/cm²/sec, 5 min duration) after pre-exposures to 5 minutes to an adapting 620 nm (red line), 480 nm (blue line) or no light (“black”, green line) compared to the normalized dark adapted reference response (black line; see temporal sequence of exposure above, further details in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005991#s2" target="_blank">Methods</a>). …”

Significantly altered metabolites in CSF of dKO rats (compared to WT) display unique metabolite-class signatures. by Samit Ganguly (1792294)

“…<p>Pie-chart showing distribution percentages of significant (p<0.05) metabolites in different metabolite classes as designated by the colors in CSF of dKO vs. WT rats (A). Volcano plots (log₁₀(q) vs. log₂(fold change)) plot of CSF metabolites identified by pathway information (color of markers) and their significance (q-value) (size of marker) (B). …”

Depletion of the macrophage niche increases conidial destruction during establishment of infection. by Felix Ellett (454831)

“…<i>nfsB-mCherry)</i> positive, treated with 10 mM metronidazole) Data are mean±SEM, n≥5 embryos/group/experiment, n≥3 experiments.…”

Biological Properties of Experimental Methacrylate-Based Sealers Containing Calcium Phosphates by Leticia Boldrin Mestieri (12791975)

“…In both viability assays, HAp and AHP sealers were similar, and α-TCP presented lower viability compared to the others at MTT assay (p<0.05). A gradual decrease of the inflammatory response according to the periods was observed and AHP was the only that presented giant cells (7-day period). …”

RanGAP1 RNA interference increased tumor cell death and cell-cycle arrest but had no effect on non-neoplastic LCL cells. by Kung-Chao Chang (170593)

“…(<b>C</b>) Western blotting shows a marked decrease (vector, 1.0 vs. shRANGAP1, 0.2 with GAPDH normalization) of RanGAP1 expression in SU-DHL-5 and HT (vector, 1.0 vs. shRANGAP1, 0.4) after RNA interference of RANGAP1 by shRNA.…”