Supplementary Material for: Knockdown of PSMB7 Induces Autophagy in Cardiomyocyte Cultures: Possible Role in Endoplasmic Reticulum Stress by Kyrychenko V.O. (4138963)

“…RNA interference that decreased the levels of non-catalytic PSMB7 subunits of the proteasome had no influence on chymotrypsin- and trypsin-like activities, but significantly decreased peptidyl-glutamyl peptide-hydrolyzing activity. …”

The time dependence of <i>R</i>, <i>k</i>, and the proportion of cases causing superspreading events. by Juliana C. Taube (12908668)

“…<p>(A) <i>R</i> decreased significantly between the first and second halves of transmission trees. …”

Table_3_Age-Related Differences in Functional and Structural Connectivity in the Spatial Navigation Brain Network.XLSX by Stephen Ramanoël (784853)

“…Nineteen young (μ = 27 years, σ = 4.3; 10 F) and 22 older (μ = 73 years, σ = 4.1; 10 F) participants were examined in this study. …”

Table_1_Age-Related Differences in Functional and Structural Connectivity in the Spatial Navigation Brain Network.XLSX by Stephen Ramanoël (784853)

“…Nineteen young (μ = 27 years, σ = 4.3; 10 F) and 22 older (μ = 73 years, σ = 4.1; 10 F) participants were examined in this study. …”

Bax and Bcl-x_L are involved in the DHA-induced apoptosis. by Tongsheng Chen (394172)

“…<p>(A) Silencing of Bax but not Bak prevented DHA-induced decreasing of cell ability assessed by CCK-8. …”

Image_1_Age-Related Differences in Functional and Structural Connectivity in the Spatial Navigation Brain Network.tif by Stephen Ramanoël (784853)

“…Nineteen young (μ = 27 years, σ = 4.3; 10 F) and 22 older (μ = 73 years, σ = 4.1; 10 F) participants were examined in this study. …”

Table_2_Age-Related Differences in Functional and Structural Connectivity in the Spatial Navigation Brain Network.XLSX by Stephen Ramanoël (784853)

“…Nineteen young (μ = 27 years, σ = 4.3; 10 F) and 22 older (μ = 73 years, σ = 4.1; 10 F) participants were examined in this study. …”

Effects of plant diversity on productivity strengthen over time due to trait-dependent shifts in species overyielding by Liting Zheng (17905028)

“…<p dir="ltr">Using data from 65 grassland and forest biodiversity experiments, we show that the temporal strength of diversity effects at the community scale is underpinned by temporal changes in the species that yield. …”

Table_1_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.docx by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_3_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_4_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_2_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_1_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Illustration of the protocol—Example 1. by Magali Tournus (11384059)

“…B: To visualize the profiles more precisely, we rescale the profiles using the real value for <i>γ</i> (i.e <i>γ</i> = 1.3) and formula <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008964#pcbi.1008964.e004" target="_blank">(3)</a>. …”

Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice by Shan Shan Qiu (840626)

“…</p><p>Results</p><p>Successful shedding was achieved in 83,3% of the xenografts. The mean time for shedding was 35±5.4 days. Statistically significant differences were found in the total area, collagen fibers area and thickness between the groups. …”

Overexpression of SERPINE2/PN-1 in human medulloblastomas. by Catherine Vaillant (9182)

“…Data for medulloblastoma (n = 437) and normal controls (n = 18) were generated by Affymetrix Human U133 Plus2.0 arrays and were MAS5.0 normalized. Grey bars represent mean values. …”

Tension between hysteresis and biphasic dose-response. by Jeffrey V. Wong (168573)

“…Hysteresis is measured by calculating the path difference 24 hours after an increase in serum from 0.01% or after a decrease from 10%. Biphasic response is measured 36 hours after an increase in MYC synthesis (parameter ke_MC; <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002491#pcbi.1002491.s007" target="_blank">Text S1</a>). …”

Statistical hypothesis testing using thermodynamic and kinetic smFRET data. by Sebastian L. B. König (502808)

“…<p>(<b>A</b>) Analysis of variance (ANOVA) of docked fractions determined by thresholding of normalized cumulated FRET histograms (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084157#pone-0084157-g006" target="_blank">Figure 6C</a>) reveals that Ni²⁺ and Co²⁺ shift the conformational equilibrium significantly towards the docked state (*** P<0.001). …”

Cellular density effect on the cytoskeleton contribution to E-[c(RGDfK)2] and iRGD internalization. by Damien Moncelet (384264)

“…Treatment with colchicine induced a strong decrease of E-[c(RGDfK)2] and iRGD uptakes. …”

Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”