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40221
Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever
Published 2011“…</p> <h3>Methodology/Principal Findings</h3><p>Here, we used a model of acute arenaviral infection in outbred guinea pigs based on challenge with an adapted strain of Pichindé virus (PICV) to further preclinical development of T-705 (Favipiravir), a promising broad-spectrum inhibitor of RNA virus infections. …”
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40222
Image_6_Maternal prebiotic supplementation impacts colitis development in offspring mice.TIF
Published 2023“…However, its role in modulating the development of other intestinal disorders, such as colitis, remains unknown. Therefore, we investigated the effects of prebiotic supplementation in pregnant mice on the occurrence of colitis in their offspring.…”
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40223
Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice
Published 2019“…To address the lack of diagnostic biomarkers, we explored miR-124, miR-183 and miR-338 in a CiPN model induced by paclitaxel, a well-known neurotoxic agent. …”
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40224
Data_Sheet_1_Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice.docx
Published 2023“…Hyperoxia leads to excess free radical production with subsequent neuroinflammation, astrogliosis, microgliosis and apoptosis. We hypothesized that Galantamine, an acetyl choline esterase inhibitor and an FDA approved treatment of Alzheimer’s disease, will reduce hyperoxic brain injury in neonatal mice and will improve learning and memory.…”
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40225
Neural timescales increase with cognitive demands.
Published 2025“…<b>(C)</b> Example of autocorrelation functions for each condition calculated on response-locked data. We hypothesized pop-out condition would show shorter timescales than the search condition. …”
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40226
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40227
Table_9_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy...
Published 2024“…Background<p>Creatinine-cystatin C ratio (CCR) has been demonstrated as an objective marker of sarcopenia in clinical conditions but has not been evaluated as an osteoporosis marker in individuals with normal renal function.</p>Methods<p>We selected 271,831 participants with normal renal function from UK Biobank cohort. …”
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40228
Table_2_Benchmarking Eco-Efficiency and Footprints of Dutch Agriculture in European Context and Implications for Policies for Climate and Environment.xlsx
Published 2019“…These emissions hardly decreased since 2000. In the current bid to meet the Paris Climate Agreement (PCA), the agricultural sector will need to reduce emission by 3.5 Mton in 2030. …”
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40229
Data_Sheet_2_Increase in presentations with new-onset psychiatric disorders in a psychiatric emergency department in Berlin, Germany during the second wave of the COVID-19 pandemic...
Published 2023“…Increases in the following diagnoses were observed: new-onset of substance-related and addictive disorders (+192.5%), depressive disorders (+115.8%), schizophrenia spectrum and psychotic disorders (+113.3%) and anxiety disorders (+63.6%). …”
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40230
Data_Sheet_1_Dynamics of urban development patterns on thermal distributions and their implications on water spread areas of Vellore, Tamil Nadu, India.docx
Published 2024“…The LULC results showed an increase in built-up lands from 5.89 to 25.89%, while zooming water areas shrank from 3.15 to 1.02%. …”
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40231
Table_1_Directional Selection of Microbial Community Reduces Propionate Accumulation in Glycerol and Glucose Anaerobic Bioconversion Under Elevated pCO2.docx
Published 2021“…Our results highlight that limited propionate conversion at elevated pCO<sub>2</sub> resulted from decreased cell viability and low abundance of syntrophic partners. …”
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40232
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40233
Image 1_Effects of different additives on fermentation quality, mycotoxin concentrations, and microbial communities in high-moisture corn kernels during wet storage.tif
Published 2024“…LAB treatment also reduced water-soluble carbohydrate (WSC) content (5.05% DM). Microbial diversity was reduced in the LAB treatment, as evidenced by decreases in both common and unique operational taxonomic units, while the relative abundance of Weissella increased after 60 days compared to CK. …”
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40234
Table_7_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy...
Published 2024“…Background<p>Creatinine-cystatin C ratio (CCR) has been demonstrated as an objective marker of sarcopenia in clinical conditions but has not been evaluated as an osteoporosis marker in individuals with normal renal function.</p>Methods<p>We selected 271,831 participants with normal renal function from UK Biobank cohort. …”
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40235
Image_3_Bacteroides thetaiotaomicron Ameliorates Experimental Allergic Airway Inflammation via Activation of ICOS+Tregs and Inhibition of Th2 Response.tif
Published 2021“…Patients with allergic rhinitis (n = 6) and healthy controls (n = 6) were enrolled, and gut microbiome composition analysis was performed by 16S rDNA sequencing. We also established an ovalbumin (OVA)-induced allergic airway inflammation murine model. …”
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40236
Image2_Respiratory support strategies in the prevention of bronchopulmonary dysplasia: A single center quality improvement initiative.jpeg
Published 2022“…</p>Methods<p>Directed by a multidisciplinary respiratory QI team, we gradually implemented the following interventions to reach our aim: (1) early initiation of non-invasive ventilation in the delivery room, (2) initiation of caffeine prior to 24 h of life, (3) administration of early selective surfactant per a well-defined guideline, (4) continuation of non-invasive ventilation until 32 and 0/7 weeks corrected gestational age (CGA), and (5) a revision of the early selective surfactant guideline. …”
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40237
Table4_Efficacy and safety of fenofibrate add-on therapy in patients with primary biliary cholangitis refractory to ursodeoxycholic acid: A retrospective study and updated meta-ana...
Published 2022“…Biochemical and clinical indicator changes in UDCA-refractory PBC patients receiving combination therapy were analyzed by Revman 5.42. Then, we explored the influence of fenofibrate dose and the effectiveness and safety of long-term application by retrospective cohort study.…”
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40238
Image1_Respiratory support strategies in the prevention of bronchopulmonary dysplasia: A single center quality improvement initiative.jpeg
Published 2022“…</p>Methods<p>Directed by a multidisciplinary respiratory QI team, we gradually implemented the following interventions to reach our aim: (1) early initiation of non-invasive ventilation in the delivery room, (2) initiation of caffeine prior to 24 h of life, (3) administration of early selective surfactant per a well-defined guideline, (4) continuation of non-invasive ventilation until 32 and 0/7 weeks corrected gestational age (CGA), and (5) a revision of the early selective surfactant guideline. …”
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40239
Association of Ficolin-3 with Severity and Outcome of Chronic Heart Failure
Published 2013“…<div><p>Background</p><p>Inflammatory mechanisms involving complement activation has been shown to take part in the pathophysiology of congestive heart failure, but the initiating mechanisms are unknown. We hypothesized that the main initiator molecules of the lectin complement pathway mannose-binding lectin (MBL), ficolin-2 and ficolin-3 were related to disease severity and outcome in chronic heart failure.…”
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40240
Table1.DOCX
Published 2018“…The NlugCSP8 mRNA was also highly expressed in the abdomen of unmated 5-day brachypterous males and correlated to the age, gender, adult wing form, and mating status. …”