Bladder hyper-permeability is present in the URO-MCP-1 IC mouse model. by Nataliya Smith (40735)

“…(D) Trans-epithelial electrical resistance (TEER) (Ω.cm²) of mouse bladders (<i>ex vivo</i>) that were either treated with saline (open squares; n = 5) or LPS (closed triangles; n = 5). There was a significant decrease in TEER in LPS-treated URO-MCP-1 mice, compared to saline-treated mice (**p<0.01). …”

BIOHYDROGEN PRODUCTION IN AnSBBR IN FED-BATCH FROM STARCH EFFLUENT: INFLUENCE OF ORGANIC LOAD by Tamiris U. Tonello (5313131)

“…However, with the increase in the organic loading rate in which the CT was reduced from 4 to 2 h (condition II to III), there was a decrease in PrM and RMCA and RMCR. The best performance of the reactor was verified in condition II (organic loading rate: 13.5 gTC L− 1 d−1; CT: 4 h), in which the PrM was 35.8 molH2 m−3 d−1 and RMCA and RMCR were 2.24 and 3.67 molH2 kgTC−1, respectively.…”

Double knockdown of <i>Gli1/Gli2</i> in XY gonads. by Kathryn S. McClelland (687254)

“…<p>(A–D) Knockdown of GLI1/GLI2 in the gonad: qRT-PCR showed that treatment with Gli1/Gli2MO (<i>n</i> = 6, 5, 5, 8) resulted in no significant downregulation in steroidogenic regulator <i>Sf1/Nr5a1</i> (A) but a significant downregulation in expression of steroidogenic pathway enzymes <i>Hsd3β</i> (B), <i>Cyp11a1</i> (C) and <i>Star</i> (D). …”

Effectiveness verification framework for coupon distribution marketing measure considering users’ potential purchase intentions by Akiko Yoneda (17823590)

Neutrophil recruitment, MMP9 secretion, and viral load are TLR-dependent. by Linda M. Bradley (173208)

“…<p>Neutrophil numbers and MMP9 secretion are decreased in TLR-deficient mice. (A–E) C57BL/6 (<i>grey bars</i>), <i>Myd88</i>^−/−, and <i>Tlr3</i>^−/− (<i>both clear bars</i>) mice were infected with 12500 EID₅₀ PR8. …”

ROP18 directly phosphorylates Irga6 at T102 and T108 in vitro. by Tobias Steinfeldt (154465)

“…<p>(A) Bacterially expressed, purified wt or T102A and T108A mutant Irga6 proteins (300 ng) were coincubated with bacterially expressed, purified GST-ROP18-Ty (10 µl, 5 µl, 1.7 µl respectively; 1 µl ∼20 ng) in the presence of γ³²P-ATP in vitro. …”

DataSheet1_Spermine oxidase induces DNA damage and sensitizes fusion negative rhabdomyosarcoma cells to irradiation.pdf by Clara Perrone (8625468)

“…Despite the multimodal heavy chemo and radiation therapeutic regimens, high risk metastatic/recurrent FN-RMS shows a 5-year survival less than 30% due to poor sensitivity to chemo-radiotherapy. …”

Data_Sheet_1_Effects of Hypoxia and Acidosis on Cardiac Electrophysiology and Hemodynamics. Is NHE-Inhibition by Cariporide Still Advantageous?.docx by Aida Salameh (584203)

“…Hypoxia and hypoxia+acidosis led to a severe deterioration of LV function with a decrease in LV pressure by about 70% and an increase of end-diastolic pressure from 6.7 ± 0.6 to 36.8 ± 5.4 (hypoxia) or from 7.0 ± 0.2 to 18.6 ± 4.1 (hypoxia+acidosis). …”

Table_1_Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats.DOCX by Gabriela Cruz-Carrillo (8925332)

“…Molecular effects of methyl modulators [S-adenosylmethionine (SAM) or 5-azatidine (5-AZA)] on pro-inflammatory cytokine expression and phagocytosis were identified in the cultures of immortalized SIM-A9 microglia cells following palmitic acid (100 μM) or LPS (100 nM) stimulation for 6 or 24 h. …”

Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Data Sheet 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Data Sheet 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 7_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 4_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …”