Articulo 017 FASEB Journal.pdf by Juan Antonio Gimenez-Bastida (6442297)

“…HKs result from the rearrangement of a di-endoperoxide intermediate formed in the COX-2-dependent oxygenation of 5<i>S</i>-hydroxyeicosatetraenoic acid (5<i>S</i>-HETE). …”

Effects of ligand stimulation and targeted therapeutics on IGF1R and IR expression and phosphorylation. by Jurriaan Brouwer-Visser (578686)

“…Measured by RT-qPCR (n = 5 independent experiments each done in triplicate) IR-A and IR-B mRNA levels in HEY-T30 are significantly decreased when compared to HEY, while similar levels are observed when comparing A2780-T15 to A2780. …”

Liraglutide Increases the Catabolism of Apolipoprotein B100–Containing Lipoproteins in Patients With Type 2 Diabetes and Reduces Proprotein Convertase Subtilisin/Kexin Type 9 Expre... by Bruno Vergès (6184907)

“…<p><b>RESEARCH DESIGN AND METHODS</b>: We performed an <i>in vivo</i> kinetic study with stable isotopes (L-[1-¹³C] leucine) in 10 T2DM patients before and after 6-month treatment with liraglutide (1.2 mg/day). …”

The evolution of persister function, with less extreme differences in persister and nonpersister survival and growth, and differences in efficiency of resource use. by Andy Gardner (92711)

“…We assume: <i>p</i>₀ = 1, <i>T</i> = 5, <i>g</i> = 0, <i>a</i> = 1 and a range of <i>z</i>₀. …”

Combined intervention of swimming plus metformin ameliorates the insulin resistance and impaired lipid metabolism in murine gestational diabetes mellitus by Liping Huang (315281)

“…Swimming or metformin intervention slightly or moderately improves hyperglycemia, insulin sensitivity and lipid metabolism both in liver and skeletal muscle from GDM mice, while combined therapy of swimming plus metformin markedly ameliorated hyperglycemia (FPG, decreased by 22.2–59.5% from G10 to G18 versus DC group), insulin sensitivity (2.1 and 2.8 fold increase, respectively, in AKT activity versus DC group) and <i>de novo</i> lipogenesis (3.2 and 7.0 fold decrease, respectively, in ACC activity, and 1.94 and 5.1 fold decrease, respectively, in SREBP2 level, versus DC group) both in liver and skeletal muscle from GDM mice. …”

Comparison of the fraction of positive relations for different behavioral updating. by Xiaochen He (455300)

“…<p>The simulation is carried out 10 times on a random network consisting of 100 nodes with average network connectivity 〈<i>k</i>〉 = 4. …”

Table1_Mitral valve aneurysms: echocardiographic characteristics, formation mechanisms, and patient outcomes.xlsx by Yi Wang (32470)

“…</p>Conclusions<p>We recommend using echocardiography as a highly sensitive method for MVA diagnosis. …”

Fetal and Childhood Exposure to Phthalate Diesters and Cognitive Function in Children Up to 12 Years of Age: Taiwanese Maternal and Infant Cohort Study by Han-Bin Huang (322180)

“…A total of 110, 79, 76, and 73 children were followed up at ages 2, 5, 8, and 11, respectively. …”

Supplementary Material for: Deranged Iron Status Evidenced by Iron Deficiency Characterizes Patients with Hidradenitis Suppurativa by Ponikowska M. (8280024)

“…<b><i>Results:</i></b> Compared with controls, patients with HS demonstrated a deranged iron status as evidenced by decreased levels of ferritin (91 ± 87 vs. 157 ± 99 µg/L), Tsat (21.5 ± 10.8 vs. 42.2 ± 11.7%) and hepcidin (31.3 ± 25.9 vs. 44.2 ± 22.0 ng/mL) (all <i>p</i> < 0.05 vs. controls). …”

Cellular starvation in <i>C. trachomatis</i>-infected cells. by Márta Szaszák (214158)

“…Quantitative analysis of τ₂-NAD(P)H (n = 54 ROIs from three independent experiments; mean±SEM). Detailed results of statistical analysis are shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002108#ppat.1002108.s012" target="_blank">Table S5A</a>. …”

Supplementary Materials - Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models by Maria V Giolito (8499600)

“…According to the need for the development of new anticancer agents, we have synthetized novel bioactive compounds and aimed to determine their antitumor action. …”

Interactions between TSC2, TBC1D7 and the TSC1delex proteins. by Arthur Jorge Santiago Lima (549061)

“…TSC1 delex18 and delex22 showed a significant decrease in the amount of coimmunoprecipitated TBC1D7 (unpaired t-test p values<0.05; indicated with asterisks). …”

The effect of Pam3CSK4 on adhesion of HMCLs to BMSCs. by Jahangir Abdi (400453)

“…Pam3CSK4 decreased adhesion of OPM-1, OPM-2, and NCI-H929 cell lines to HS-5 in a dose-dependent manner. …”

The DEDI-domain of caspase 8 is critical for its interaction with Bcl2. by Mahbuba Rahman (198499)

“…<p>Vectors containing mutations in specific domains (DEDI, putative binding(PB), DEDII) of caspase 8 were transiently transfected into (<b>A</b>) MIP/5FU, MiaPaca/CPT or (<b>B</b>) MIP/SP cells, to determine the ability of the mutant proteins to co-IP with Bcl2 or SPARC. …”

DOR binding is enhanced by CB₁R ligands in membranes of cells expressing CB₁R and DOR. by Ittai Bushlin (191060)

“…Data represent Mean ± SEM (n = 3 experiments in triplicate). <b>B,</b> Membranes from N2A-DOR cells in which CB₁R expression was decreased by siRNA transfection were treated with 100 fM – 10 µM Hu-210 in the presence of 0.5 nM [³H]DPDPE. …”

Data Sheet 1_Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.docx by Hua Huang (190195)

“…Immunohistochemical analysis of UC lesion samples revealed diminished expression levels of GNG5 and elevated expression levels of TIMP1. A dextran sulfate sodium (DSS)-induced colitis mouse model was developed, demonstrating that the protein expression levels of GNG5 in the colonic tissue of model mice were significantly decreased compared to controls w)ile the expression levels of TIMP1 were increased (p < 0.01). …”

Clinical consequences of weight loss during stem cell transplantation. by Christina T. Rieger (838986)

“…<p>A: No difference in overall survival between patients that lose ≥ 5% of BMI during SCT B: Similar result for a BMI decrease of ≥ 10%. …”

Thymoquinone reverses learning and memory impairments and brain tissue oxidative damage in hypothyroid juvenile rats by Yousef Baghcheghi (4791297)

“…Both 5 mg/kg and 10 mg/kg doses of TQ decreased latency time in the Morris water maze test and increased delay in entering the dark compartment in a passive avoidance test. …”

Comparison of diet, age, and insulin signaling effects on CHCs. by Tatyana Y. Fedina (114609)

“…<p>Arrows indicate an increase or decrease in the relative abundance of individual CHCs: 1) for aging - from young to old age on balanced diets <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049799#pone.0049799-Kuo1" target="_blank">[18]</a>, 2) for protein – based on change from S5Y5 to S5Y20, and for sugar – based on change from S5Y5 to S20Y5, 3) for insulin signaling (IIS) - change in transgenic flies with increased insulin signaling (via insulin receptor overexpression - InR^OX) or decreased insulin signaling (insulin substrate mutants <i>chico</i>) compared to controls <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049799#pone.0049799-Kuo2" target="_blank">[19]</a>. …”

Movie S1 - Quantifying Exocytosis by Combination of Membrane Capacitance Measurements and Total Internal Reflection Fluorescence Microscopy in Chromaffin Cells by Ute Becherer (74949)

“…This cell was stimulated for 2 s by depolarizing pulses and is shown 4 s prior to and 8.5 s after stimulation. Secretion of vesicles seen as a sharp decrease of fluorescence of individual spots (highlighted by white arrows) occurs simultaneously to the increase in membrane capacitance and only during the stimulation period (marked in red). …”