Agmatine treatment reduced the gliosis activation following SCI. by Yu Mi Park (275600)

“…</b> The GFAP expressions were substantially decreased after SCI in the Agm treated group (<i>n</i> = 5) compared with the EC group (<i>n</i> = 5). …”

Steroidogenic programme is differently regulated in the XX and XY gonads of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> mice. by Alejo Torres-Cano (12878169)

“…<p>(A) Immunostaining for NR5A1 (red) and nuclear DAPI staining (blue), using sections of gonads from XY and XX control and <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> E14.5 mice. …”

Mutations at p53 binding sites augment PIK3CA promoter activity. by Snehal M. Gaikwad (279479)

“…Representative bioluminescent images of the mice bearing tumors of A2780-MPFT3 cells. Mouse from control and treated group exhibited specific [Fig. 5e3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 5e3 (post-treatment)].…”

PIAS1 inhibits the ability of TGFβto suppress E-cadherin promoter activity. by Stuart J. Netherton (152258)

“…Aii) Each column is the mean (± SEM, n = 5) of the percent repression of luciferase activity by TGFβ relative to that of the basal (− TGFβ) of the corresponding transfection as shown in Ai (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013971#s4" target="_blank">MATERIALS and METHODS</a>). …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”

Effects of cannabinoid receptor antagonism on pancreatic stellate cells. by Christoph W. Michalski (85727)

“…<p>(A) MTT assays after 48 hours' incubation of PSC with graded concentrations of CB1- and CB2-receptor antagonists AM251 and AM630 (p = n.s. for concentrations of 1.25, 2.5 and 5 µM). …”

Longitudinal MRI study of changes in BTB permeability and rCBV of brain metastases. by Heling Zhou (368949)

“…All the tumors except one (yellow arrowhead) still kept BTB intact at week 4. rCBV maps were created and rCBV values of the tumors were presented in the table (<b>B</b>). <b>C.</b> A total of 32 lesions in 5 animals were seen on both scans of weeks 3 and 4. rCBV of brain metastases (solid) was initially similar to that of contralateral normal brain (open; mean  = 1.05±0.05 (se) vs. 0.96±0.04), but decreased significantly (p<0.05) and became significantly lower as compared to their contralateral normal brain in the late scan (mean  = 0.88±0.06 vs. 1.00±0.06; p<0.05).…”

Schematic of experimental paradigms. by Shiva Farashahi (5018381)

“…A central yellow bar represented the probability of reward (between 0.5 and 1.0), while the peripheral arc indicated the amount of reward. …”

Ndrg2 mRNA is induced in wt mice by FXR agonists, reduced in livers of FXR^−/− versus wt mice and both FXR and NDRG2 mRNAs are reduced in human HCC versus normal liver.... by Ulrich Deuschle (129085)

“…Relative mRNA levels of Ndrg2, Shp, Cyp7a1 and Cyclophilin E were determined by RT-qPCR from wt (n = 5) and FXR^−/− (n = 5) mice as indicated. …”

Study on the properties of oil-water interface after the interaction between ionized water and naphthenic acid by Qin Guowei (22155073)

“…The results show that after the action, the interfacial tension of oil and water continues to decrease, and 1/3 ionized water (salinity diluted to 1/3 of the prepared ionized water, 1253 ppm) decreases to a maximum of 50.89%, while 1/5 ionized water (752 ppm) only decreases 14.40%; the thickness of the oil-water interface film decreases with the salinity of ionized water, but the decrease increases after 1/3 ionized water. …”

Table_1_Altered Urinary Amino Acids in Children With Autism Spectrum Disorders.XLSX by Aiping Liu (149453)

“…Using support vector machine modeling and receiver operating characteristic curve analysis, we identified a panel of 7 UAA indicators that discriminated between the samples from ASD and TD children (lysine, 2-aminoisobutyric acid, 5-hydroxytryptamine, proline, aspartate, arginine/ornithine, and 4-hydroxyproline). …”

Image_1_Altered Urinary Amino Acids in Children With Autism Spectrum Disorders.PNG by Aiping Liu (149453)

“…Using support vector machine modeling and receiver operating characteristic curve analysis, we identified a panel of 7 UAA indicators that discriminated between the samples from ASD and TD children (lysine, 2-aminoisobutyric acid, 5-hydroxytryptamine, proline, aspartate, arginine/ornithine, and 4-hydroxyproline). …”

<i>In vitro</i> validation of VH411 phage binding. by Marion David (366485)

“…In the present example, the cells were incubated with the anti-PVIII antibody (1/1000) detected with an allophycocyanine (APC) secondary antibody (1/800) (vertical axis) (B1, B3, B4, B5, B6) and with the anti-LDLR antibody (1/50) detected with a secondary FITC-labeled antibody (1/800) (horizontal axis) (B2, B3, B4, B5, B6). …”

Effect of population size on the magnitude of distortion. by Alexander Coulton (8468724)

“…The dashed lines mark the 5% significance threshold for a chi-square test, whilst the dotted line marks a 1:1 segregation ratio. …”

Metabolites displaying the highest differences between TCF7L2 risk genotype carriers and controls. by Cornelia Then (81529)

“…Delta t35 (p = 2.7E-03) and t240 (p = 4.2E-03) of PC ae C40:5 are given as a representative example. Data are given as mean and standard error of the mean. * = p ≤ 0.05 after correction for multiple testing.…”

Empagliflozin Reduces Liver Fat in Diabetic and Nondiabetic Subjects by Siham Abdelgani (17756772)

Table_1_The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongating B... by Sofia Esquivel-Elizondo (4438618)

“…However, this was considerably higher at 83.1 ± 0.44% when both fructose and n-butyrate (electron acceptor) were combined as a substrate. A comparison of 7D4C2 cultures with fructose and n-butyrate with an increasing pH value from 4.5 to 9.0 showed a decreasing n-caproate specificity from ∼92% at mildly acidic pH (pH 4.5-5.0) to ∼24% at alkaline pH (pH 9.0). …”

Data_Sheet_1_The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongat... by Sofia Esquivel-Elizondo (4438618)

“…However, this was considerably higher at 83.1 ± 0.44% when both fructose and n-butyrate (electron acceptor) were combined as a substrate. A comparison of 7D4C2 cultures with fructose and n-butyrate with an increasing pH value from 4.5 to 9.0 showed a decreasing n-caproate specificity from ∼92% at mildly acidic pH (pH 4.5-5.0) to ∼24% at alkaline pH (pH 9.0). …”

Data Sheet 1_Valve-in-valve transcatheter aortic valve replacement (TAVR) leads to lower device success compared to TAVR in native stenosis.pdf by Michael Paukovitsch (16428786)

“…While ViV-TAVR decreased peak and mean gradients significantly, in 31% of patients elevated mean gradients (≥20 mmHg) were observed at discharge. …”

Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice by Mike Kalogiannis (224818)

“…The muscarinic antagonist atropine (0.5 mg/kg, IP) decreased the number of arrests, also without altering arrest lifetimes. …”