Mouse phenotyping identified 200 BMD genes. by Anna L. Swan (9922965)

“…<p>(A) Of the 3,823 genes deleted in mice, 200 or 5% caused a change in BMD phenotype. …”

Effects of cooperativity on effective energetic contribution of hotregions. by Rudi Agius (454506)

“…Effectively, the additive hotspot energy assumption results in hotregions contributing in a linearly increasing manner according to their size, the negative cooperativity assumption results in hotregions contributing in an increasing exponential-like manner as the hotregions increase in size, and the positive cooperativity assumption results in hotregions reaching a maximum contribution at around a hotregion size of 5, with their contribution decreasing beyond.…”

Global proteomic changes upon perturbation of Hsp90. by Teresa R. O’Meara (720286)

“…Non-denaturing IEX fractionation and MS experiments were performed on <i>lys2Δ/lys2Δ tetO-HSP90/hsp90Δ</i> cells that were untreated, treated with DOX to repress <i>HSP90</i> expression, or treated with 15 μM GdA to inhibit Hsp90 function. For DOX treatment, cells were treated with 0.05 μg/mL DOX overnight and then subcultured into medium with 5 μg/mL DOX for 4 hours before harvesting. …”

Evidence for rapid downward fecundity selection in an ectoparasite (Philornis downsi) with earlier host mortality in Darwin’s finches by Sonia Kleindorfer (95761)

“…Across a 12-year period, we observed a mean of ~17% P. downsi mortality in host nests with 55 ± 6.2 % host mortality, and a trend of ~66% higher host mortality throughout the study period. …”

DataSheet_1_Alteration of Gut Microbiome and Correlated Lipid Metabolism in Post-Stroke Depression.pdf by Wenxia Jiang (3567782)

“…The microbial composition of PSD showed a decreased species richness indices, characterized by 22 depleted OTUs mainly belonging to phylum Firmicutes, genus Blautia and Streptococcus. …”

Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages by Qing Li (84975)

“…To identify candidate regulatory mechanisms, we compared the global and selected targeted mRNA expression patterns of pituitaries collected from beef steers that had been randomly assigned to undergo summer-long grazing (89 to 105 d) of a high-toxic endophyte-infected tall fescue pasture (HE; 0.746 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 10; BW = 267 ± 14.5 kg) or a low-toxic endophyte tall fescue–mixed pasture (LE; 0.023 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 9; BW = 266 ± 10.9 kg). …”

Distal cue novelty task. by Desiree R. Seib (5249750)

“…<p>A) Rats decreased exploration of the objects over the 6 trials (Mauchly’s test P = 0.2; trial effect, F_5,135 = 44, P<0.001, partial η² = 0.62) and did not increase exploration upon changes to the distal context on trial 6 (trial 6 vs trials 1–4 all P<0.01, trial 6 vs trial 5 P = 0.3). …”

DataSheet_1_Risk Factors for Adverse Neurodevelopment in Transient or Persistent Congenital Hyperinsulinism.docx by Marcia Roeper (9704393)

“…In univariate analysis, mildly abnormal neurodevelopment was associated with the diagnosis of persistent CHI (odds ratio (OR) 8.3; p=0.004) and higher birth weight (mean difference 1049 g; p<0.001). Severe hypoglycemic brain injury was associated with the diagnosis of persistent CHI (OR 5.1; p=0.013), being born abroad (OR 18.3; p<0.001) or in a lower-level maternity hospital (OR 4.8; p=0.039), and of note history of hypoglycemic seizures (OR 13.0; p=<0.001), and a delay between first symptoms of hypoglycemia and first blood glucose measurement/initiation of treatment (OR 10.7; p<0.001). …”

FGFR1-Frs2/3 pathway is required for the specification of prosensory domain. by Kazuya Ono (513633)

“…<p>(A–C) p27^Kip1 (magenta) is expressed in the post-mitotic, BrdU (green) negative, prosensory domain (bracket) in sections of E14.5 cochlea (A). …”

Mrj knockout shows reduced Orb2 oligomers. by Meghal Desai (15201231)

“…The data underlying this figure are available at: <a href="https://figshare.com/s/f5d913a0a289339ee16b" target="_blank">https://figshare.com/s/f5d913a0a289339ee16b</a>.…”

Pdd1 dephosphorylation does not occur in by Annie Wan Yi Shieh (459701)

“…<div><p>Δ<i>LIA5 </i><b>conjugation </b><b>cells</b>.</p> <p>(A) anti-Pdd1 western blot analysis of total protein isolated from conjugating WT, <i>∆LIA5</i> and <i>∆DCL1</i> at indicated time point. …”

Differentiation of T_FH cells is required for efficient establishment of MHV68 latency in B cells. by Christopher M. Collins (309503)

“…Flow plots were gated on CD4+ cells, and T_FH cells are defined as CXCR5^HI, PD-1^HI (representative flow plots are shown in panel A). …”

Table_1_The Biomechanical Characteristics of the Strongman Yoke Walk.XLSX by Benjamin R. Hindle (10698531)

“…Kinematic and spatiotemporal measures of hip and knee joint angle, and mean velocity, stride length, stride rate and stance duration of each 5 m interval were taken whilst 19 strongman athletes performed three sets of a 20 m yoke walk at 85% of their pre-determined 20 m yoke walk one repetition maximum. …”

Mechanisms of short-term synaptic plasticity in the TM model. by Maurizio De Pittà (194237)

“…(<b>B</b>) The latter monotonically decreases for input frequencies larger than the limiting frequency (<i>f</i>_lim, <i>dashed line</i>) for a depressing synapse (<i>red shaded area</i>). …”

Eigenvalue stability in the LHIGP module. by Amanda L. Caskenette (3692260)

“…<p>Patterns of stability for Cases 1–4 (a-d) starting from a food chain module and moving towards an exploitative competition module as <i>m</i> & <i>s</i> decrease from 1 to 0 (Parameter values: r = 1.5, K = 1, a_CR = 3, a_PC = 1, a_PR = 0.2, b_CR = 1.5, b_PC = 1, b_<i>PR</i> <i>= 1</i>, d_C = 0.3 (b and d), 0.5 (a and c), d_P = 0.1 (c and d), 0.15(a and b)).…”

Cooperatively coupled cargo translocation. by Aidan I. Brown (509994)

“…<p>(A) Cytosolic PEX5-cargo concentration vs. PEX5 cargo addition rate, . …”

Leukocyte infiltration signatures of human psoriasis and mouse psoriasiform lesions. by William R. Swindell (175427)

“…For each set of <i>n</i> signature transcripts associated with a given cell population, and for each psoriasiform phenotype, we identified the number of transcripts with increased expression in mouse psoriasiform lesions (<i>n</i>₁) and the number of transcripts with decreased expression in mouse psoriasiform lesions (<i>n</i>₂). …”

Image_1_Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice.tif by Satoshi Yamaga (15344251)

“…Moreover, CIRP-/- mice exhibited increased survival after 6.5-Gy TBI compared to WT mice. Interestingly, TREM-1 expression on peritoneal macrophages in CIRP-/- mice was significantly decreased compared to that in WT mice at 24 h after 10-Gy TBI. …”

Supramolecular Structures and Assembly and Luminescent Properties of Quinacridone Derivatives by Kaiqi Ye (1436131)

“…In contrast, high efficiencies (21.5−12.0 cd/A) are achieved for a wider dopant concentration range of 0.5−5.0% when Alq₃:<b>2</b> films are employed as emitting layer. …”

Presentation_1_CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.pptx by Alexander T. H. Cocker (8436300)

“…We found in 757 individuals, from a combined 28 studies and 6 datasets, that the CD56neg subset constitutes 5.67% of NK cells in healthy peripheral blood, while HIV-1 infection increases this population by a mean difference of 10.69%. …”