Image_1_A New Enantiornithine (Aves) Preserved in Mid-Cretaceous Burmese Amber Contributes to Growing Diversity of Cretaceous Plumage Patterns.PDF by Lida Xing (309643)

“…Here, we describe a new specimen that consists of the distal extremities of both forelimbs and hindlimbs. …”

Data_Sheet_1_Analyses on Flavonoids and Transcriptome Reveals Key MYB Gene for Proanthocyanidins Regulation in Onobrychis Viciifolia.docx by Zhongzhiyue Jin (12917399)

“…Among them, the expression levels of F3'5'H and ANR were higher in leaves than in roots or stems, which is consistent with proanthocyanidins content in these tissues. …”

DataSheet1_Different Monoclonal Antibodies in Myasthenia Gravis: A Bayesian Network Meta-Analysis.docx by Zhaoming Song (11475394)

“…</p><p>Results: In indicators of efficacy, patients receiving eculizumab (MD, −1.9; 95% CI, −3.2–0.76) had decreases in MG-ADL scores compared to placebo. In addition, only eculizumab (MD, −3.1; 95% CI, −4.7–1.5) and efgartigimod (MD, −1.4; 95% CI, −2.1–0.68) showed a significant difference from placebo in the amount of reduction in QMG scores, while neither of the other two monoclonal antibodies was statistically significant. …”

Effect and mechanism of BDNF/TrkB signaling on vestibular compensation by Dehong Mao (11630876)

“…BDNF and TrkB levels after UL were determined by western blot and quantitative reverse transcription PCR (qRT-PCR). 5-bromo-2ʹ-deoxyuridine (BrdU)-positive cells (newly generated cells) and GAD67-positive cells (GABAergic neurons) were identified by immunohistochemistry. …”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …”

DataSheet6_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

FA_<i>x</i>Cs_1–<i>x</i>PbI₃ Nanocrystals: Tuning Crystal Symmetry by A‑Site Cation Composition by Julian A. Vigil (1768927)

“…All compositions crystallize in the perovskite structure; however, the average structure lowers in symmetry from the α (cubic) to β (tetragonal) to γ (orthorhombic) perovskite phases with decreasing <i>x</i> (Cs addition). The corresponding α- to β- and β- to γ-phase transitions occur between <i>x</i> = 0.75–0.5 and <i>x</i> = 0.25–0.1, respectively. …”

Table_1_The resource (in)sufficiency of the Caribbean: analyzing socio-metabolic risks (SMR) of water, energy, and food.DOCX by Francisco Martin del Campo (15443117)

“…</p>Results<p>Our findings point to the decreasing availability of all three resources within the Caribbean region. …”

Image_2_Genome Analysis Coupled With Transcriptomics Reveals the Reduced Fitness of a Hot Spring Cyanobacterium Mastigocladus laminosus UU774 Under Exogenous Nitrogen Supplement.TI... by Mayuri Mukherjee (11009623)

“…Among genes showing extreme downregulation when grown in a medium supplemented with nitrogen with the fold change > 5 are transcriptional regulator gene WalR, carbonic anhydrases, RNA Polymerase Sigma F factor, fimbrial protein, and twitching mobility protein. …”

Image1_Porcn is essential for growth and invagination of the mammalian optic cup.TIF by Sabine Fuhrmann (14033082)

“…However, it is unclear whether this also applies to mammals. We performed ubiquitous conditional inactivation of Porcn in mouse around the eye field stage. …”

Image_2_MiR-539-3p impairs osteogenesis by suppressing Wnt interaction with LRP-6 co-receptor and subsequent inhibition of Akap-3 signaling pathway.tif by Alok Tripathi (7054172)

“…MicroRNAs sequence analysis showed differentially regulated miRNAs in phex silenced osteoblast cells. In this article, we report miR-539-3p, an unidentified novel miRNA, in the functional regulation of osteoblast. …”

Table_1_A Proteomics Signature of Mild Hypospadias: A Pilot Study.pdf by Coriness Piñeyro-Ruiz (9912183)

“…For the most part, a limited number of cases have known etiology. We have followed a high-throughput proteomics approach to study the proteome in mild hypospadias patients.…”

Maternal and neonatal outcomes of repeated antepartum bleeding in 493 placenta previa cases: a retrospective study by Shiyun Huang (172702)

“…<p> To explore the effect of antepartum bleeding caused by PP on pregnancy outcomes.</p> <p> We retrospectively analyzed 493 pregnant women complicated with PP. …”

Table 1_Antibacterial activity and mechanism of Sodium houttuyfonate against heteroresistant Pseudomonas aeruginosa.docx by Zhihong Li (176839)

“…However, the increasing rate of emergence of heteroresistant strains poses a therapeutic challenge. Therefore, we examined the antibacterial activity of Sodium houttuyfonate (SH, a compound derived from Houttuynia cordata) in combination with Meropenem (MEM) against heteroresistant Pseudomonas aeruginosa and investigated the mechanism of Sodium houttuyfonate.…”

Comprehensive Analysis of the Proteome and PTMomes of C2C12 Myoblasts Reveals that Sialylation Plays a Role in the Differentiation of Skeletal Muscle Cells by Xiulan Chen (1538248)

“…Inhibition of sialylation with the sialyltransferase inhibitor 3Fax-Neu5Ac resulted in the lower expression of MHC and suppression of myoblast fusion. …”

Artificial intelligence-based prescription of personalized scalp cosmetics improved the scalp condition: efficacy results from 100 participants by Bo Ri Kim (18364882)

“…<p><b>Background:</b> Scalp-related symptoms such as dandruff and itching are common with diverse underlying etiologies. We previously proposed a novel classification and scoring system for scalp conditions, called the scalp photographic index (SPI); it grades five scalp features using trichoscopic images with good reliability. …”

DataSheet9_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Image_2_Responses of phytoplankton communities driven by differences of source water intrusions in the El Niño and La Niña events in the Taiwan Strait during the early spring.tif by Yanping Zhong (12618612)

“…Although the monsoonal patterns were similar during early spring cruises during two ENSO events, the influence of the China Coastal Current (CCC), which is characterized by low sea surface temperature, low salinity, and high nutrient concentrations, was 1.5 times greater during the 2015–2016 El Niño than the 2017–2018 La Niña. …”

Site-specific fracture incidence rates among patients with type 1 diabetes, type 2 diabetes or without diabetes in Denmark (1997-2017) by Annika Vestergaard Kvist (14307189)

“…Median IRs for the first (1997-2001) and the last (2013-2017) five years were compared. We estimated age-adjusted IR ratios (IRRs) of fractures among patients with type 1 and type 2 diabetes to patients without diabetes, using Poisson models.…”

Leveraging Vulnerabilities in Copper Trafficking for Synergistic Antifungal Activity by Catherine A. Denning-Jannace (22449392)