Data_Sheet_1_Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium.DOCX by Ana Álvarez-Barrios (15301603)

“…Conversely, increased levels of Cu (1.5-fold in cytoplasm, 5.0-fold in cell nuclei and membranes), Na (3.5-fold in cytoplasm, 14.0-fold in cell nuclei and membranes) and K (6.8-fold in cytoplasm) were detected after 59-days long culture. …”

320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection by Daddy Mata-Mbemba (5746847)

“…</p><p>Methods</p><p>50 consecutive patients (82.6±6.9 years; 56% female) were prospectively enrolled and underwent a TAVR planning using a 320-row CT, with ECG-gated aortic root CTA immediately followed by a non-gated aorto-iliac acquisition, all within a single bolus of 40-70mL of Iohexol 350mgI/mL. …”

Overexpression of Rab26 restricts insulin secretion in β-cells. by Ruijuan Zhuang (3938915)

Effect of AQHAR on hnRNP-K and mortalin, tumor metastasis mediating proteins, in A549 and U2OS cells. by Kejuan Li (2580184)

Table_1_The impact of the COVID-19 pandemic on chlamydia infection in South Korea: a comparison between the pre-pandemic and during-pandemic periods.docx by Achangwa Chiara (12999578)

Image_1_The impact of the COVID-19 pandemic on chlamydia infection in South Korea: a comparison between the pre-pandemic and during-pandemic periods.JPEG by Achangwa Chiara (12999578)

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…</p>Method<p>A total of 22 patients with brain metastases were retrospectively enrolled. …”

Divergent signalling pathways mediate the effects of Aβ on Homer1b and Shank1 cluster dispersal. by Francesco Roselli (211670)

“…Wort+Aβ and Wort alone; p<0.05). Notably, wortmannin itself decreased Shank1 (but not Homer1b) cluster size (74.3±10.3%, cf. …”

Table_1_The responses of soil microbial characteristics to nitrogen addition and biochar amendment in a Larix kaempferi plantation.docx by Chen Hu (317374)

“…However, the impacts of biochar on the microbial characteristics of soil after short-term N deposition in subtropical plantations remain poorly understood. Here, we investigated the effects of biochar application (0, 5, 10 t ha⁻¹) on soil chemical traits and microbial characteristics (extracellular enzyme activities, microbial community and microbial biomass) in a Larix kaempferi plantation in Shennongjia, China, under N addition (0, 50, 100 kg N ha⁻¹ yr⁻¹) during two growing seasons. …”

Interplay between fungicides and parasites: Tebuconazole, but not copper, suppresses infection in a <i>Daphnia-Metschnikowia</i> experimental model by Ana P. Cuco (3775534)

“…Most importantly, while copper and parasite effects were mostly independent, tebuconazole suppressed infection. In a follow-up experiment, we tested the effect of a lower range of tebuconazole concentrations (0.00, 6.25, 12.5, 25.0, 50.0 and 100 μg L^-1) crossed with increasing parasite challenge (2 <i>Daphnia</i> clones × 6 contaminant concentrations × 2 parasite levels × 20 replicates = 480 experimental units). …”

Identification of Chalcones as <i>Fasciola hepatica</i> Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach by Florencia Ferraro (3146766)

“…One of the compounds, <b>C34</b>, tightly bounds to juvenile specific <i>Fh</i>CL3 with an IC₅₀ of 5.6 μM. We demonstrated that <b>C34</b> is a slow-reversible inhibitor that interacts with the Cys-His catalytic dyad and key S₂ and S₃ pocket residues, determinants of the substrate specificity of this family of cysteine proteases. …”

Assessing the benefits of five years of different approaches to treatment of urogenital schistosomiasis: A SCORE project in Northern Mozambique by Anna E. Phillips (4050331)

“…<i>haematobium</i> was seen in adults even in the SBT arms implying the rate of transmission in the community had been decreased, even where only school children have been treated, which has significant logistical and cost-saving implications for a national control programme in justifying CWT.…”

Comparative RNA-Seq data for <i>L</i>. <i>interrogans</i> sv. Manilae L495 wild-type and <i>perRA/B</i> strains cultivated in dialysis membrane chambers (DMCs). by André A. Grassmann (11141592)

Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and meta-analysis by Luling Lin (7586510)

“…</p><p>Methods and findings</p><p>We searched OvidMedline, Embase, Cochrane CENTRAL, and Cochrane Database of Systematic Reviews from inception to April 1, 2019, and <a href="http://controlled-trials.com" target="_blank">controlled-trials.com</a>, clinicaltrials.gov, and <a href="http://anzctr.org.au" target="_blank">anzctr.org.au</a>. …”

LBH589 induced DNA fragmentation and cell cycle disorder in SK-NEP-1 and G401 cells. by Tao Yan-Fang (770096)

“…<p>(A) Micrographs following Hoechst 33342 staining of cells treated with LBH589 (50 nM and 100nM) for 24 h. …”

image2_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Table_1_Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review.pdf by Martine Bellanger (4101313)

“…The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. …”

Table_3_Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review.pdf by Martine Bellanger (4101313)

“…The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. …”

image2_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Complement to Fig 7—A p53-dependent response promotes tissue development when nuclear reassembly is compromised. by Jingjing Li (7654)

“…Wings discs of indicated genotypes were incubated with EdU for 1 h and then co-stained for DNA (DAPI) and cleaved Dcp-1. Scale bar: 50 μm. Coordinate values used to generate graphs are available in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002780#pbio.3002780.s016" target="_blank">S1 Data</a>.…”