Expression of BDNF in retinas after 6 weeks of diabetes onset in SE- or EE-housed animals. by Damián Dorfman (293002)

“…Data are the mean ± SEM (n = 5 eyes per group); **p<0.01, versus age-matched controls; a: p<0.01, versus diabetic animals housed in SE, by Tukey's test. …”

Acute TTBK1 inhibition reduces tau phosphorylation at disease relevant sites <i>in vivo</i>. by Gregory M. Dillon (8681430)

“…<p>We administered the TTBK1 inhibitor, BIIB-TTBK1i, at 25, 50, and 75mg/kg, five minutes prior to isoflurane-induced hypothermia in 2-month-old, male C57Bl/6 mice (n = 3 mice per dose group). …”

Fertility of gilts immunized with sperm membranes or lipid rafts. by Nathaly Cormier (4775262)

“…High immunity to SMA or SLRA produced a 3.8-fold decrease in litter size (from 10.5 to 3.3 piglets/litter, <i>p</i> = 0.0119).…”

Dysplasia_Clinical.xlsx by Dani Gaillard (2744839)

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…Moreover, in our center's experience, neither arrhythmia burden, nor contractility have worsened in the vast majority of patients: we note a clinically insignificant mean decrease in left ventricular ejection fraction (LVEF), with only two patients requiring temporary mavacamten discontinuance for LVEF < 50%. …”

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…Moreover, in our center's experience, neither arrhythmia burden, nor contractility have worsened in the vast majority of patients: we note a clinically insignificant mean decrease in left ventricular ejection fraction (LVEF), with only two patients requiring temporary mavacamten discontinuance for LVEF < 50%. …”

Video_2_Electrophysiological Characterization of Human Atria: The Understated Role of Temperature.MOV by Rupamanjari Majumder (128411)

“…However, not much is known about the influence of temperature on other important characterization parameters such as the resting membrane potential (RMP), excitability, morphology and characteristics of the action potential (AP), restitution properties, conduction velocity (CV) of signal propagation, etc. Here we present the first, detailed, systematic in silico study of the electrophysiological characterization of cardiomyocytes from different regions of the normal human atria, based on the effects of ambient temperature (5−50°C). …”

Video_1_Electrophysiological Characterization of Human Atria: The Understated Role of Temperature.MOV by Rupamanjari Majumder (128411)

“…However, not much is known about the influence of temperature on other important characterization parameters such as the resting membrane potential (RMP), excitability, morphology and characteristics of the action potential (AP), restitution properties, conduction velocity (CV) of signal propagation, etc. Here we present the first, detailed, systematic in silico study of the electrophysiological characterization of cardiomyocytes from different regions of the normal human atria, based on the effects of ambient temperature (5−50°C). …”

Data_Sheet_1_Electrophysiological Characterization of Human Atria: The Understated Role of Temperature.pdf by Rupamanjari Majumder (128411)

“…However, not much is known about the influence of temperature on other important characterization parameters such as the resting membrane potential (RMP), excitability, morphology and characteristics of the action potential (AP), restitution properties, conduction velocity (CV) of signal propagation, etc. Here we present the first, detailed, systematic in silico study of the electrophysiological characterization of cardiomyocytes from different regions of the normal human atria, based on the effects of ambient temperature (5−50°C). …”

OCM impairment is involved in ethanol impact on DNA repair in the PFC. by Anna-Kate Fowler (625791)

“…(B) DNA repair activity in the PFC of WT and <i>Mthfr+/−</i> mice exposed to acute and chronic ethanol. Values are means ± SEM; *p<0.01; **p<0.005; ***p<0.002. Note a decrease in DNA repair activity in the PFC following 3-week (3 w) and even more so following 5 week (5 w) exposure, compared with acute alcohol exposure and a significant exaggeration of this decrease by MTHFR deficiency.…”

Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…The mean age of the group was 51.5 years (95% CI: 50.6-52.3) in 2003 and 51.3 years (95% CI: 50.6-52.0) in 2011. …”

Temporal Trends in Exposures to Six Phthalates from Biomonitoring Data: Implications for Cumulative Risk by Jeanette M. Reyes (1306353)

“…Over this period, there was a 2.2-fold decrease in the mean HI (0.34 to 0.15) and a 7.2-fold decrease in the percentage of participants with an HI > 1 (5.7% to 0.8%), indicating an overall decrease in combined exposure to these phthalates. …”

Supplementary Material for: Calcium-Alkali Syndrome Associated with Hypoparathyroidism Following Total Thyroidectomy by Kuroya S. (8343321)

“…All patients received calcium lactate and alfacalcidol for postsurgical hypocalcemia. We defined hypercalcemia as a corrected serum calcium level (cCa) ≥10.5 mg/dL, metabolic alkalosis as a difference in serum sodium and serum chloride ([sNa-sCl]) ≥39 mEq/L, and renal impairment as a ≥50% increase in serum creatine and/or ≥35% decrease in estimated glomerular filtration rate (eGFR) compared to baseline. …”

Data_Sheet_1_Prognosis and Risk Factors of Radiation-Induced Lymphopenia in Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy.zip by Qianqian Zhao (712029)

“…Spearman's correlation coefficients between post-SBRT TLC and the percentage of the lung and heart receiving 5 to 50 Gy (in 5 Gy increments) shown that most lung DVH parameters [V(10)-V(50)] were significantly negatively correlated with post-SBRT TLC, while only heart V(5), V(20), V(25), V(30), and V(45) were significant. …”

Image_1_Prognosis and Risk Factors of Radiation-Induced Lymphopenia in Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy.tif by Qianqian Zhao (712029)

“…Spearman's correlation coefficients between post-SBRT TLC and the percentage of the lung and heart receiving 5 to 50 Gy (in 5 Gy increments) shown that most lung DVH parameters [V(10)-V(50)] were significantly negatively correlated with post-SBRT TLC, while only heart V(5), V(20), V(25), V(30), and V(45) were significant. …”

New Targets for Drug Discovery against Malaria by Guido Santos (171018)

“…The potential targets include: 1) increasing the death rate of the gametocytes, 2) decreasing the invasion rate of the red blood cells by the merozoites, 3) increasing the transformation of merozoites into gametocytes, 4) decreasing the activation of the immune system by the gametocytes, and finally 5) a combination of the previous target with decreasing the recycling rate of the red blood cells. …”

Image_2_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Image_3_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Image_1_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Image_4_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”