Table_2_Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 Patients.docx by Linna Huang (3837052)

“…Current users of ACEIs/ARBs seemed to have a higher rate of vasoconstrictive agents (20 vs. 6%, P < 0.01) than the control group. Decreased lymphocyte counts [(0.76 ± 0.31) vs. (1.01 ± 0.45)^*10⁹/L, P = 0.027] and elevated plasma levels of IL-10 [(9.91 ± 0.42) vs. (5.26 ± 0.21) pg/ml, P = 0.012] were also important discoveries in the ACEI/ARB group. …”

Study selection flow diagram. by Laurence Weinberg (2960238)

“…Respiratory, cardiac, renal, neurologic, gastrointestinal, and/or infectious complications were reported in 19%, 20%, 14%, 18%, 5%, and 9% of cases, respectively. The median length of hospital stay was 12.5 days (IQR 10.4–18.0). …”

DataSheet1_Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells.docx by Valentina Brunetti (18861187)

“…The direct stimulation of TRPML1 with both the synthetic agonist, ML-SA1, and the endogenous ligand phosphatidylinositol 3,5-bisphosphate (PI(3,5)P₂) induced a significant increase in [Ca²⁺]_i, that was reduced by pharmacological blockade and genetic silencing of TRPML1. …”

Impacts of pellet pH on nitrous oxide emission rates from cattle manure compost pellets by Tsuyoshi Yamane (3318771)

“…To investigate the mechanism by which N₂O emission rates and cumulative emissions were reduced in nitrogen-enriched manure composts pellets (N+MCP), we studied the impact of pellet pH on N₂O emission, because pH is different between MCP (pH 8.6) and N+MCP (pH 5.3). …”

Inclusion and exclusion criteria. by Laurence Weinberg (2960238)

“…Respiratory, cardiac, renal, neurologic, gastrointestinal, and/or infectious complications were reported in 19%, 20%, 14%, 18%, 5%, and 9% of cases, respectively. The median length of hospital stay was 12.5 days (IQR 10.4–18.0). …”

Data_Sheet_1_Multimodal Optical Imaging to Investigate Spatiotemporal Changes in Cerebrovascular Function in AUDA Treatment of Acute Ischemic Stroke.docx by Han-Lin Wang (8638884)

“…At post-stroke day 7, a 105.4% ± 16.4% increase of astrocytes (p < 0.01), 30.0 ± 10.9% increase of neurons (p < 0.01), and 65.5 ± 15.0% decrease of microglia (p < 0.01) were observed in the penumbra region in AUDA-treated rats (N = 5 for each group). …”

Key characteristics of the included publications. by Laurence Weinberg (2960238)

“…Respiratory, cardiac, renal, neurologic, gastrointestinal, and/or infectious complications were reported in 19%, 20%, 14%, 18%, 5%, and 9% of cases, respectively. The median length of hospital stay was 12.5 days (IQR 10.4–18.0). …”

Presumed Little Ice Age glacial extent in the eastern Tian Shan, China by Yanan Li (94033)

Smn deficiency in SMA type I axon terminals <i>in</i><i>vivo.</i> by Benjamin Dombert (648183)

“…Acetylcholine receptors (AChR) and postsynaptic nuclei were visualized by ω-BTX and DAPI, respectively (scale bar: 5 µm). In (A) Smn deficiency is visible by highly reduced immunoreactive signals, as highlighted in the white box, whereas in (B) the number of Smn particles per NMJ is decreased in SMA type I motor endplates, as indicated by white arrowheads. …”

<i>In vitro</i> 6xHis-CBU0823 activity assays for ME (A), LDH (B) and MDH (C) function, including the influence of varied pH (D), and substituted cofactors (E and F). by Janine Hofmann (11273418)

“…<p>(A) ME activity was observed for 20 μg 6xHis-CBU0823 in the ME standard assay containing 3 mM malate, 5 mM NAD⁺, 1 mM MnCl₂. 28.8 μg 6xHis-oMLE and 6xHis-mock purification negative control had no activity. …”

SNX-1, IWN3* and RME-8 expression levels control RME-8 microdomain localization and positioning. by Anne Norris (268484)

“…Each data point is an individual worm, error bars indicate Mean with 95% CI, student t-test statistical analysis done on ratiometric data, and ANOVA on Pearson’s correlation data, with p < .5 = *, p < .01 = **, p < .001 = ***. …”

2-AA down-regulates the transcription of many genes involved in the translational capacity of the cell. by Yok-Ai Que (70055)

“…Exogenously added 2-AA decreases polysomes levels. Ribosomal extracts from PA14 cells grown in the absence (left panel) or presence (right panel) of exogenously added 2-AA were separated in a 25% to 5% sucrose density gradient. …”

SBDS expression is downregulated during human cord blood CD34⁺ neutrophil differentiation. by Claudia Orelio (217728)

“…(B) Representative quantitative RT-PCR analysis shows that SBDS mRNA expression decreases 5-fold with human cord blood neutrophil differentiation (n = 3; mean±SEM). …”

Lactate levels in conditioned medium from breast cell lines under normoxia and hypoxia. by Nicola J. Brown (380651)

“…In MDA-MB-436 cells the mean lactate levels decreased slightly from 38.5 µM to 34.5 µM per 1×10⁶ cells (-0.9 fold change), but was not statistically significant (p = 0.229). …”

Data_Sheet_1_Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma.ZIP by Claudia Siebert (7004594)

“…In functional assays, among five different compounds tested luminespib and ganetespib induced a significant decrease in cell viability in single as well as in combined treatments with compounds of the clinically used EDP-M scheme (etoposide, doxorubicin, cisplatin, mitotane). …”

Humidity, density, and inlet aspiration efficiency correction improve accuracy of a low-cost sensor during field calibration at a suburban site in the North-Western Indo-Gangetic p... by Harshita Pawar (8351919)

“…During the monsoon period (16 June–25 July 2016) the MBE of the PM_2.5 measurements decreased from 19.1 µg m⁻³ to 8.7 µg m⁻³ and from 28.3 µg m⁻³ to 16.5 µg m⁻³ for Sensor 1 and Sensor 2, respectively, after correcting for particle density and hygroscopic growth. …”

Hunchback directly represses <i>eve3+7</i>. by Ben J. Vincent (5727950)

“…We perform the same analysis in wild-type embryos to account for modulation along the DV axis. …”

Effect of E cell connectivity topology on network dynamics with single peak <i>g</i>_<i>Ks</i> distribution. by Yihao Yang (480313)

“…<p>A, Power of network theta and gamma rhythms as a function of E cell synaptic connection rewiring probability with a single <i>g</i>_<i>Ks</i> hotspot (r = 5.7). It shows the drastic decrease of theta rhythm across the network as network E-cells’ connections became less local. …”

Table 1_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx by Stefanie Wagner (743707)

“…Following tylosin application, flow cytometry-based cell counting revealed decreased absolute abundances of five families and ten genera. …”

Impact of Appropriate Antimicrobial Therapy for Patients with Severe Sepsis and Septic Shock – A Quality Improvement Study by Paula K. O. Yokota (655314)