Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Table_1_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Data_Sheet_1_Diabetes Mellitus Is an Independent Risk Factor for a Stiff Left Atrial Physiology After Catheter Ablation for Atrial Fibrillation.PDF by Moon-Hyun Kim (12044069)

“…After 1:3 propensity score (PS) matching for age, sex, and AF type, we compared 211 patients with DM with 633 patients without DM. …”

Presentation_1_Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy.pdf by Yvette Wooff (4955854)

“…Isolated s-mEV from normal retinas were characterized using dynamic light scattering, transmission electron microscopy and western blotting, and quantified across 5 days of photo-oxidative damage-induced degeneration using nanotracking analysis. …”

Table 1_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…In addition, we demonstrated that HIF1α and HIF2α promoted IGF1R expression by binding to a specific hypoxia response element (HRE) sequence (5′-GAACGTGCCT-3′) within the IGF1R promoter using dual-luciferase reporter system.…”

Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

The complete workflow employed in this study. by Md. Mostafa Kamal (13514317)

“…Out of these, 186 missense variants (5.93%), 1491 intron variants (47.57%), and 91 synonymous variants (2.90%), while the remaining SNPs were unspecified. …”

Data_Sheet_1_Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition.pdf by Mayssa Albouery (8294364)

“…Transplantation of microbiota from old mice also modified the lipid class and fatty acid content in the liver. Finally, we found that the expression of several genes involved in MUFA and PUFA synthesis (Scd1, Fads1, Fads2, Elovl2, and Elovl5) was dysregulated in mice inoculated with an aged microbiota. …”

Table 2_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…For trend analysis, we employed annual percentage change (EAPC) through linear regression and applied Joinpoint analysis to identify significant changes over time. …”

DataSheet_1_Treatment-Induced BAFF Expression and B Cell Biology in Multiple Sclerosis.docx by Ide Smets (10875969)

“…Protein BAFF correlated with an increase in transitional B cells (P = 5.70 x 10^-6), decrease in switched B cells (P = 3.29 x 10^-4), and reduction in B cell-surface BAFF-R expression (P = 2.70 x 10^-10), both on TACI-positive and -negative cells. …”

Table 3_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…For trend analysis, we employed annual percentage change (EAPC) through linear regression and applied Joinpoint analysis to identify significant changes over time. …”

Long-Term Neurobehavioral and Metabolic Outcomes in Offspring of Mothers with Diabetes During Pregnancy: A large, population-based cohort study in Ontario, Canada. by Denice S Feig (18546680)

“…</p><p dir="ltr">Research Design and Methods</p><p dir="ltr">We conducted a population-based, cohort study of deliveries in Ontario between April 1991, and March 2018. …”

A Global Analysis of the Effectiveness of Marine Protected Areas in Preventing Coral Loss by Elizabeth R. Selig (138602)

“…We found that on average, coral cover within MPAs remained constant, while coral cover on unprotected reefs declined. …”

Data_Sheet_1_Physical Exercise Induces Immunoregulation of TREG, M2, and pDCs in a Lung Allergic Inflammation Model.docx by Paula Fernandes (290060)

“…The EX and OEX groups underwent moderate aerobic physical exercise from days 21 to 51 (5 d/w, 1 h/d). The mice were euthanized on day 52. …”

Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Bl... by figshare admin karger (2628495)

“…Introduction: perturbation-based balance training reduces fall rates dramatically by triggering and improving balance recovery skills. We aimed to investigate whether multidirectional surface perturbation treadmill training, which explicitly challenges age-related impairments in reactive responses, can improve balance recovery responses in standing and reduce annual falls. …”

Trypanosoma cruzi induces changes in gene expression of glucocorticoid and prolactin receptors in CD4⁺CD8⁺ cells and alters their sensitivity to GC-induced ap... by Ailin Lepletier (328461)

“…However, if we evaluate the ratio of vehicle-treated over DEX-treated cells (panel <b>B</b> right) the sensitivity to DEX-induced apoptosis on CD4⁺CD8⁺ thymocytes is significantly decreased as disease progresses. …”

Table 2_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…In addition, we demonstrated that HIF1α and HIF2α promoted IGF1R expression by binding to a specific hypoxia response element (HRE) sequence (5′-GAACGTGCCT-3′) within the IGF1R promoter using dual-luciferase reporter system.…”

Table 4_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…In addition, we demonstrated that HIF1α and HIF2α promoted IGF1R expression by binding to a specific hypoxia response element (HRE) sequence (5′-GAACGTGCCT-3′) within the IGF1R promoter using dual-luciferase reporter system.…”

Defining Hypo-Methylated Regions of Stem Cell-Specific Promoters in Human iPS Cells Derived from Extra-Embryonic Amnions and Lung Fibroblasts by Koichiro Nishino (219736)

“…Thus, a group of genes becomes active through a decrease of methylation in their promoters. Twenty-three genes including <em>SOX15</em>, <em>SALL4</em>, <em>TDGF1</em>, <em>PPP1R16B</em> and <em>SOX10</em> as well as <em>POU5F1</em> were defined as genes with hypo-methylated SS-DMR (Stem cell-Specific Differentially Methylated Region) and highly expression in iPS/ES cells.…”