Mefloquine treatment decreases cochlear outer and inner hair cell survival, while NAD⁺ treatment protects the hair cells. by Dalian Ding (385461)

3-aminobenzamide decreased nuclear SIRT1 expression without modifying its activity, demonstrating basal SIRT1 activity increase. by Cindy Gueguen (526035)

A novel antibiotic-impregnated implant coating results in reduced <i>S. aureus</i> infection, decreased inflammation and prevention of biofilm formation. by Nicholas M. Bernthal (129760)

MiR-133a expression decreases cancer metastasis <i>in vivo</i> and associates with longer survival rates in NSCLC patients. by Lu-Kai Wang (562118)

hMSC adjunctive therapy failed to decrease pulmonary inflammation or prevent ALI compared to antiviral therapy alone in experimental severe influenza. by Ilyse Darwish (446378)

“…<p>Eight-week old male C57Bl/6 mice infected with 425 EID₅₀ influenza A/PR/8 virus were administered 2.5 mg/kg oseltamivir in 100 ul ddH2O via gavage, 1×daily for 5 days, beginning day 2 P.I., with or without hMSC administration (5×10⁵ cells) on day 2 P.I. and sacrificed on day 7 P.I. …”

NRX-1 localization to cholinergic axons is decreased in <i>unc-104</i> mutants and colocalizes with UNC-104 in cholinergic axon terminals. by Devyn Oliver (12015660)

TGF-β1 had little effect on MMP-2, MMP-3 and MMP-14 expression, but decreased expression of MMP-16. by Youssef M. Farhat (295089)

Longitudinal phenotypic study of late-onset retinal degeneration due to a founder variant c.562C>A p.(Pro188Thr) in the <i>C1QTNF5</i> gene by Julie De Zaeytijd (3633118)

“…</p> <p><b>Results</b>: Best-corrected visual acuity (BCVA) and visual fields were maintained up to 50 to 55 years (n = 8), with a gradual decline, but conservation of functional central vision between 55 to 65 years (n = 15), followed by a steep decrease in overall visual function beyond 65 years (n = 9). …”

Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a time-dependent manner. by Lan Zhang (90951)

Ephrin-A2 and –A6 expression and EphA4 Tyr-602 phosphorylation decrease from nasal to temporal RGCs. by Ana Laura Ortalli (159899)

Supplementary Material for: Optimistic Youth: Young Adults Predicted a Faster Decrease in Risk during COVID-19 Emergency State in Portugal by Scaletti S. (12434691)

Image 1_Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development—potential mediation by glucocorticoid receptor.pdf by S. Spulber (19335583)

“…Using a continuous developmental exposure regime, we show that wildtype larvae exposed to GBH display decreased spontaneous activity and attenuated response to environmental stimuli, a pattern of alteration similar to the one observed in gr^s357 mutant larvae. …”

Image 2_Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development—potential mediation by glucocorticoid receptor.pdf by S. Spulber (19335583)

“…Using a continuous developmental exposure regime, we show that wildtype larvae exposed to GBH display decreased spontaneous activity and attenuated response to environmental stimuli, a pattern of alteration similar to the one observed in gr^s357 mutant larvae. …”

A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes by Sharon Cresci (53599)

“…Consistent with previous descriptions of PPARα in experimental models and human disease, we describe a novel <em>PPARA</em> promoter SNP that decreases transcriptional activation of <em>PPARA</em> and protects against mortality in diabetic patients after ACS.…”

Table_1_Potential Impact of Umbilical-Cord-Blood Procalcitonin-Based Algorithm on Antibiotics Exposure in Neonates With Suspected Early-Onset Sepsis.docx by Noémie Huetz (8271138)

“…The global antibiotics prescription rate was 4.6% [95% confidence interval (CI), 4.1–5]. With the PCT-based algorithm, the potential decrease in prescription rate would be 1.8% (95% CI, 1.3–2.3), corresponding to a 39% (95% CI, 37.3–40.7) relative reduction in antibiotics exposure (p < 0.05).…”

BECN1 knockdown and BCL-W/BCL2 co-inhibition decreases cell proliferation through increased apoptosis in resistant cells. by Anatasha C. Crawford (255140)

Th2 cytokines and IgE were decreased in G-1-treated BALB/c mice compared to non-treated controls. by Masamichi Itoga (706167)

The pathogenicity of <i>Radopholus similis</i> to tomato plants is decreased significantly after soaking with <i>Rs-crt</i> dsRNA. by Yu Li (183836)

Heterologous Immunity Triggered by a Single, Latent Virus in <i>Mus musculus</i>: Combined Costimulation- and Adhesion- Blockade Decrease Rejection by Jonathan M. Beus (441623)

“…<div><p>The mechanisms underlying latent-virus-mediated heterologous immunity, and subsequent transplant rejection, especially in the setting of T cell costimulation blockade, remain undetermined. To address this, we have utilized MHV68 to develop a rodent model of latent virus-induced heterologous alloimmunity. …”

Effect of lysosomal hydrolysis inhibition on the decrease of PrP^Sc levels induced by CPZ or U18666A treatment. by Takeshi Yamasaki (521196)