table2_Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.pdf by Jordi Rodon (201558)

“…Here, we have screened existing drugs approved for human use in a variety of diseases, to compare how they counteract SARS-CoV-2-induced cytopathic effect and viral replication in vitro. …”

image1_Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.jpeg by Jordi Rodon (201558)

“…Here, we have screened existing drugs approved for human use in a variety of diseases, to compare how they counteract SARS-CoV-2-induced cytopathic effect and viral replication in vitro. …”

table4_Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.pdf by Jordi Rodon (201558)

“…Here, we have screened existing drugs approved for human use in a variety of diseases, to compare how they counteract SARS-CoV-2-induced cytopathic effect and viral replication in vitro. …”

PM26, a specific antagonist of DC-SIGN, can inhibit DC-SIGN/S protein interaction and trans-infection of VSV/SARS-CoV-2. by Michel Thépaut (7462022)

“…Statistical significance was calculated in panel D by t-test (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001). The IC₅₀ value for PM26 was estimated using GraphPad Prism v8 with a 95% confidence interval and settings for normalize dose-response curves (IC₅₀ = 94 nM, 95%CI = 35 nM– 249 nM).…”

A PRISMA flowchart illustrated the selection of studies included in our systematic review. by Chenyi Ye (2697208)

Hsp72 overexpression decreases total NF-κB-p65 in resting cells and reduces steady state IκBα protein levels. by Patrick W. Sheppard (586664)

“…Data points for p65 are the averages from n = 5 independent measurements, each normalized with respect to the initial amount of p65 in untreated BV2 cells. …”

Relationship of differential distribution in 5mC and 5hmC between the obese and lean placental epigenomes to gene expression. by Kohzoh Mitsuya (4521304)

“…(C) Functional enrichment analysis of biological process for the significant overlap between genes with increased 5mC and reciprocally decreased 5hmC. The graph shows GO biological process terms associated with 262 common genes exhibited reciprocal increase in 5mC and decrease in 5hmC in placentas of the obese compared to lean mothers.…”

Fission of a stable group does not change the rank class of individual horses but induces higher numbers of affiliative interactions. by Sonja Schmucker (13261951)

Placenta-Enriched LincRNAs <i>MIR503HG</i> and <i>LINC00629</i> Decrease Migration and Invasion Potential of JEG-3 Cell Line by Bruna Rodrigues Muys (2588305)

“…Further analysis, using a cancer cell lines panel, showed that <i>MIR503HG and LINC00629</i> were expressed in 50% and 100% of the cancer cell lines, respectively. …”

Image_5_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

Ly49C peptide dependent recognition of H-2K^b decreases with peptides bearing non-polar aliphatic auxiliary anchor residues. by Elsa A. Marquez (766160)

Flipping the Switch: Reverse-Demand Voltage-Sensitive Fluorophores by Jack T. McCann (13047830)

“…Our group has been developing voltage-sensitive fluorophores (VF dyes) that respond to changes in biological membrane potential (<i>V</i>_m). We hypothesize that the mechanism of voltage sensitivity arises from acceptor PeT (a-PeT) from an electron-rich aniline-containing molecular wire into the excited-state fluorophore, resulting in decreased fluorescence at negative <i>V</i>_m. …”

Effects of <em>APOA5 −1131T>C</em> (rs662799) on Fasting Plasma Lipids and Risk of Metabolic Syndrome: Evidence from a Case-Control Study in China and a Meta-Analysis by Chunxiao Xu (311834)

“…<div><p>The apolipoprotein A5 (<i>APOA5</i>) gene <i>−1131T>C</i> (rs662799) has been suggested to be involved in the pathway of lipid homeostasis and the development of metabolic syndrome (MetS). …”

<i>Trcyc8</i> or <i>Trtup1</i> repression resulted in a significant decrease in the transcription of cellulase gene and <i>xyr1</i> transcription. by Lei Wang (6656)

The number of mGE-derived cIN is reduced in <i>Nkx2</i>.<i>1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: <i>In vitro</i>, kinetic, and <i>in silico</i> studies... by Sumaira Javaid (7886897)

Effect of control or Notch3 ASOs administered subcutaneously to C57BL/6 wild type mice on <i>Notch3</i> mRNA. by Ernesto Canalis (516050)

Fig 2 - by Ernesto Canalis (516050)

Effect of control or Notch3 ASOs on <i>Notch3</i> mRNA expression and cell replication in calvarial osteoblast-enriched cells. by Ernesto Canalis (516050)

Representative experimental samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”