Data_Sheet_4_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Table1_Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model.DOC by Victor Sokolov (14181554)

“…Even so, this association remained flat, with a 50% decrease in the basal insulin dose from pretreatment level, resulting in ∼5% increase in glucose exposure. …”

A pro-inflammatory and pro-fibrogenic cytokine profile developed in infected iNOS-KO rats. by Jia Shen (1828945)

Associations of baseline plasma BK and the sum of all unmodified bradykinin peptides with the ratio (5-year/baseline) of Sv(PGBM/glom) in the 243 RASS participants. by Kevin M. Wheelock (4237609)

“…Values above the dashed line reflect an increase in Sv(PGBM/glom) and those below the line a decrease over 5 years.</p>…”

Expression of the miR-34 family, Axl and HNF4A in RCC. by Helena K. Fritz (785130)

“…<p>The levels of miR-34a, Axl mRNA, and HNF4A mRNA were determined using RT-qPCR in a cohort of RCC patients (cohort N = 198, ccRCC N = 152, normal N = 50). …”

Schematic overview of molecular processes altered during disease progression in the SN of PD, identified using transcriptome analysis. by Anke A. Dijkstra (756877)

“…In addition, we observed down regulation of mRNA levels of the upstream regulators in mTOR pathway. …”

Estimated demographic history in four simple demographic scenarios with seed banking where <i>μ</i> = 2.5 × 10⁻⁹. by Thibaut Paul Patrick Sellinger (8677419)

“…We have <i>β</i> = 1 (red), 0.5 (blue), 0.2 (green) and 0.1 (purple). …”

The procurement of innovation by the U.S. government by Gaétan de Rassenfosse (7207697)

“…<div><p>The U.S. government invests more than $50 billion per year in R&D procurement but we know little about the outcomes of these investments. …”

Thalamic DBS modulates VPC occurrence over acute and longer time frames. by Michelle J. Redinbaugh (13029044)

Liver expression of LDLR and ABCA1 protein in mice with hepatic MTP knockdown. by Stephanie M. Marshall (223125)

Hepatic and intestinal MTP expression following MTP ASO treatment. by Stephanie M. Marshall (223125)

Heme exposure of HO-1KO A549 cells leads to lysosomal rupture and loss of viability which is prevented by pre-incubation with DFO. by Lilibeth Lanceta (782925)

Chemical and siRNA-mediated inhibition of catalase activity in A549 cells enhances the cytotoxic effects of heme. by Lilibeth Lanceta (782925)

O-GlcNAc immunoprecipitation (IP) for carnitine palmitoyltransferase 1B (CPT1B). by Wei Zhong Zhu (14014073)

Data_Sheet_1_Transient Receptor Potential Cation Channel Subfamily V Member 4 Mediates Pyroptosis in Chronic Obstructive Pulmonary Disease.docx by Yafei Rao (7310363)

Video5_Evaluation of women’s aging influence on sperm passage inside the fallopian tube using 3D dynamic mechanical modeling.MP4 by Mayssam Nassir (18351408)

Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease by Yaru Jiang (17458815)

“…Notably, patients with <i>ATP6V0A4</i> mutations were diagnosed at a younger age (mean 0.5 years) and exhibited more severe renal impairment, including reduced estimated glomerular filtration rate (eGFR), indicating heightened susceptibility to kidney damage. …”

<i>Pbpp6</i> gene deletion/disruption and analysis. by Yonghui Feng (12227596)

Cytokine and chemokine production is impaired in the liver of infected iNOS-KO rats. by Jia Shen (1828945)

The <i>sf3b1-698</i> mutants are defective in fecundity and lifespan. by Bei Zhang (428038)

“…Females of the two sf3b1 mutants laid no significantly changed eggs during the late half of test time. Means: WT = 175, H698D = 195.5, p = 0.5296, H698R = 173.4, p = 0.9437. …”