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we decrease » _ decrease (Expand Search), teer decrease (Expand Search), use decreased (Expand Search)
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18421
Table_2_Rab5b-Associated Arf1 GTPase Regulates Export of N-Myristoylated Adenylate Kinase 2 From the Endoplasmic Reticulum in Plasmodium falciparum.xlsx
Published 2021“…Here, we report the identification of PfRab5b associated proteins and dissect the pathway regulated by PfRab5b. …”
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18422
Table_1_Rab5b-Associated Arf1 GTPase Regulates Export of N-Myristoylated Adenylate Kinase 2 From the Endoplasmic Reticulum in Plasmodium falciparum.xlsx
Published 2021“…Here, we report the identification of PfRab5b associated proteins and dissect the pathway regulated by PfRab5b. …”
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18423
Suppression of neurodegeneration associated with diverse misfolded proteins in invertebrate models by <i>ufd-2</i> and <i>spr-5</i> loss-of-function mutations.
Published 2015“…Left: micrographs show the SOD1<sup>G85R</sup>-YFP proteins expressed in WT or the <i>spr-5(by134);ufd-2(tm1380)</i> mutant background. The double-mutant worms show a marked decrease in protein aggregation in neurons. …”
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18424
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18425
Presentation_1_Constructing a prognostic risk model for Alzheimer’s disease based on ferroptosis.zip
Published 2023“…Moreover, RT-qPCR showed that with the increase of Aβ<sub>1–42</sub> concentration, the expression of POR decreased first and then increased; RUFY3 was firstly increased and then decreased.…”
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18426
Presentation_2_Constructing a prognostic risk model for Alzheimer’s disease based on ferroptosis.pdf
Published 2023“…Moreover, RT-qPCR showed that with the increase of Aβ<sub>1–42</sub> concentration, the expression of POR decreased first and then increased; RUFY3 was firstly increased and then decreased.…”
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18427
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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18428
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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18429
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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18430
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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18431
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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18432
Presentation5_Orbital Influence on Precipitation, Fire, and Grass Community Composition From 1.87 to 1.38 Ma in the Turkana Basin, Kenya.PDF
Published 2021“…This included vegetation surveys and phytolith production data for species from areas proximal to the basin. We found that phytolith and microcharcoal concentrations decreased predictably moving off shore. …”
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18433
An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties
Published 2020“…<i>In silico</i> docking of 50K compounds to the NTD domain of TDP-43 identified a small molecule (nTRD22) that is bound to the N-terminal domain. …”
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18434
Presentation 1_Case Report: Full recovery in severe ParvovirusB19 myocarditis with DCM phenotype: the impact of rASD and PAB.pptx
Published 2025“…The pressure gradient across the PAB ranged from 40 to 45 mmHg, and LVEDD decreased to a mean z-score of +3.5. Within three to six months, LVEDD normalized, and LV-EF increased to a mean of 63% (range: 57%–68%). …”
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18435
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18436
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18437
Electrically Induced Liquid Metal Droplet Bouncing
Published 2022“…This is the first study of liquid metal droplet bouncing using continuous AC electrowetting through an analytical model, computational fluid dynamics simulation, and empirical validation to the best of our knowledge. We achieved liquid metal droplet bouncing with a height greater than 5 mm with an actuation voltage of less than 10 V and a frequency of less than 5 Hz. …”
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18438
Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback Inhibition
Published 2011“…Transcription factors Stat5a and Stat5b were involved in SOCS6 gene upregulation leading to neuronal differentiation. …”
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18439
Supplementary Material for: TGF-β1 inhibition of ACE2 mediated by miRNA uncovers novel mechanism of SARS-CoV-2 pathogenesis.
Published 2023“…To understand whether TGF-β1 modulates COVID-19 severity by affecting ACE2 levels in the airway, we performed small RNAseq and microRNA profiling and identified pathways uniquely affected by TGF-β1, including those associated with SARS-CoV-2 invasion. …”
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18440