Amx that only possesses the highly conserved TM2 domain is a potent inhibitor of Notch signaling. by Jose L. Salazar (3233190)

“…A 3xHA epitope (grey hexagon) was inserted after a predicted signal sequence (SS, blue box). …”

Deficiency of CD74 in mature B cells does not affect tumor proliferation. by Bianca Pellegrino (20314999)

The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers by Kristian Magnus Gundersen (7382027)

“…Measurements were taken at baseline; before a 5-min suprasystolic forearm occlusion; and following a 3-min post-occlusion, to measure reactive hyperemia and FMD.…”

Data_Sheet_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.PDF by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Mapping changes in patterning after inhibition of Notch activity. by Matthew French (13007466)

“…<p><b>A:</b> Culture method where a posterior explant of an E8.5 embryo is cultured in N2B27 media with the Notch inhibitor LY at 150 nM or an equal amount of DMSO for 12 h. …”

Laboratory animal welfare and human attitudes: A cross-sectional survey on heterospecific play or “rat tickling” by Megan R. LaFollette (3911140)

“…</p><p>Methods</p><p>Laboratory animal personnel were recruited from widespread online promotion. A total of 794 personnel (mean = 40±11 years, 80% white, 80% female) completed at least 50% of the mixed methods online survey and met inclusion criteria of currently working with laboratory rats in the USA or Canada. …”

Basis Set Limit CCSD(T) Energies for Extended Molecules via a Reduced-Cost Explicitly Correlated Approach by Mihály Kállay (1512775)

“…The new method can provide, e.g., reaction energies and barrier heights well within chemical accuracy for molecules with more than 40 atoms within a few days using a few dozen processor cores, and calculations with 50+ atoms are still feasible. …”

Table_2_Beginning of the Pandemic: COVID-19-Elicited Anxiety as a Predictor of Working Memory Performance.docx by Daniel Fellman (8583429)

“…Our results contribute to the understanding of cognitive–affective reactions to a major disaster.</p>…”

Analysis of a chromosomal deficiency that removes both <i>sup-35</i> and <i>pha-1</i>. by Kumaran Mani (262977)

“…Furthermore, the decrease in embryonic lethality is proportional to the transmission frequencies of the individual arrays; <i>fdEx77</i> and <i>fdEx75</i> exhibit transmission frequencies of 50% (n = 140) and 39% (n = 182), respectively. …”

Table_1_Beginning of the Pandemic: COVID-19-Elicited Anxiety as a Predictor of Working Memory Performance.DOCX by Daniel Fellman (8583429)

“…Our results contribute to the understanding of cognitive–affective reactions to a major disaster.</p>…”

Detection of aberrant methylation patterns in AML cell lines by MLPA using the P041A probe mixture by Anders O. H. Nygren (10615)

“…When compared to control DNA samples, a reduced probe signal specific for the and promoters is seen as shown by the black arrows, indicating a decrease in copy number of these genes [(b), 193 and 355 bp fragments]. …”

High-intensity focused ultrasound (HIFU) therapy for benign thyroid nodules: a 3-year retrospective multicenter follow-up study by Hervé Monpeyssen (9672810)

“…Complications and side effects were classified according to the Interventional Radiology Guidelines and changes in local symptoms were scored on a visual-analog scale.</p> <p> Sixty-five patients (mean age 51.1 ± 14.0 years; 86.2% women) with a single thyroid nodule and a mean baseline nodule volume of 9.8 ± 10.3 mL were treated with a mean energy of 7.1 ± 3.1 kJ (range: 2.0 to 15.5 kJ). …”

Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate <i>N</i>-acetylgalactosaminyltransferase-1 and -2 by Miki Shimbo (819991)

“…Quantitative RT-PCR analysis of E18.5 cartilage showed that the expression levels of <i>Col2a</i>1 and <i>Ptch1</i> transcripts tended to decrease in DKO compared with those in WT mice. …”

Exposure Assessment for Estimation of the Global Burden of Disease Attributable to Outdoor Air Pollution by Michael Brauer (675317)

“…Between 1990 and 2005 a 6% increase in global population-weighted PM_2.5 and a 1% decrease in global population-weighted ozone concentrations was apparent, highlighted by increased concentrations in East, South, and Southeast Asia and decreases in North America and Europe. …”

PRMT5 stabilizes vCyclin protein expression in a manner dependent on its methyltransferase activity. by Danping Niu (10912688)

“…The expression of vCyclin proteins were examined by immunoblotting (A) and qPCR (B). The relative band intensities of vCyclin from three biological replicates were graphically plotted at the bottom (A). …”

Non-randomized trial assessments. by Suzanne M. Connolly (21512209)

“…We hypothesized that it would lead to a reduction of trauma symptoms and improve grades in reading and math.…”

Image_1_Case Report: Mature Plasmacytoid Dendritic Cell Proliferation Associated With a Lymphoid Neoplasm.tiff by Fei Fei (794241)

“…<p>Mature plasmacytoid dendritic cell proliferations (MPDCPs) are clonal, non-malignant pDC proliferations that have been reported to occur in association with myeloid neoplasms such as CMML, AML (pDC-AML), and, rarely, MDS or MPNs. Here we report the first case of a MPDCP associated with T-lymphoblastic leukemia (T-ALL), a lymphoid neoplasm. …”

Image_3_Case Report: Mature Plasmacytoid Dendritic Cell Proliferation Associated With a Lymphoid Neoplasm.tiff by Fei Fei (794241)

“…<p>Mature plasmacytoid dendritic cell proliferations (MPDCPs) are clonal, non-malignant pDC proliferations that have been reported to occur in association with myeloid neoplasms such as CMML, AML (pDC-AML), and, rarely, MDS or MPNs. Here we report the first case of a MPDCP associated with T-lymphoblastic leukemia (T-ALL), a lymphoid neoplasm. …”

Image_2_Case Report: Mature Plasmacytoid Dendritic Cell Proliferation Associated With a Lymphoid Neoplasm.tiff by Fei Fei (794241)

“…<p>Mature plasmacytoid dendritic cell proliferations (MPDCPs) are clonal, non-malignant pDC proliferations that have been reported to occur in association with myeloid neoplasms such as CMML, AML (pDC-AML), and, rarely, MDS or MPNs. Here we report the first case of a MPDCP associated with T-lymphoblastic leukemia (T-ALL), a lymphoid neoplasm. …”

Synergistic Proinflammatory Responses by IL-17A and Toll-Like Receptor 3 in Human Airway Epithelial Cells by Kazutaka Mori (254785)

“…Although increases in IL-17A expression were observed in the airway of severe asthma patients, the interaction between IL-17A and TLR activation in airway epithelium remains poorly understood. In this study, we demonstrated that IL-17A and polyI:C, the ligand of TLR3, synergistically induced the expression of proinflammatory cytokines and chemokines (G-CSF, IL-8, CXCL1, CXCL5, IL-1F9), but not type I interferon (IFN-α1, -β) in primary culture of normal human bronchial epithelial cells. …”