Tamoxifen injection induced efficient recombination within <i>Cdc25A</i> and <i>Cdc25B</i> loci. by Gwanghee Lee (271155)

“…The PCR primers detect transcript arising from the null allele but not the deleted floxed allele. Thus, a 50% decrease in relative expression indicates complete loss of <i>Cdc25B</i> expression.…”

An ice-obligate seabird responds to a multi-decadal decline in Arctic sea ice - age and state demographic parameters by George Divoky (17982751)

“…<p dir="ltr">The Arctic has experienced greatly decreased sea ice and increased ocean temperatures in recent decades but there is a paucity of biological time-series data allowing assessment of resulting temporal variation in the region’s marine ecosystems. …”

Transcriptomic analysis of the long-lived and short-lived Atg1 over-expressing flies reveals altered immunity and mitochondrial function. by Ivana Bjedov (75652)

NO concentration and iNOS expression in RGK36 cells. by Hiromi Kurokawa (7377806)

Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study by figshare admin karger (2628495)

“…Prior research has validated the correlation between antibodies directed towards the cysteine-rich(CysR) and C-type lectin 1, 7, and 8(CTLD1, CTLD7, and CTLD8) domains of PLA2R1 and outcomes in MN. Methods: In a prospective cohort of 52 patients with newly diagnosed PLA2R1-MN, with urine protein ≥ 3.5 g/24 hours and estimated glomerular filtration rate ≥30 mL/min/1.73 m², we studied epitope-spreading patterns and domain-specific PLA2R1-Ab clinically using western blot and ELISA. …”

Image_1_Aspirin Use on Incident Dementia and Mild Cognitive Decline: A Systematic Review and Meta-Analysis.tif by Hui Li (32376)

“…However, low-dose aspirin (75–100 mg/day) was associated with a decreased likelihood of developing dementia or MCI (the pooled RR = 0.75; 95% CI = 0.63–0.9; Ifor heterogeneity2 = 50.5%). …”

Table1_Enhancing decellularized vascular scaffolds with PVDF and PCL reinforcement: a fused deposition modeling approach.docx by Kirill Yu. Klyshnikov (11151429)

“…In contrast, both PVDF and PCL reinforced scaffolds did not exhibit significant property degradation, with deformations ranging 0.1–0.13 mm depending on the model, and a maximum decrease in the modulus of elasticity of 23%.…”

Intranasal Ketamine as an Adjunct to Fentanyl for the Prehospital Treatment of Acute Traumatic Pain: Design and Rationale of a Randomized Controlled Trial by Jason McMullan (9357677)

“…The proportion achieving a reduction of ≥2-points will be compared between study arms using a Chi-square test. …”

Use of Patient-Specific Instrumentation (PSI) for glenoid component positioning in shoulder arthroplasty. A systematic review and meta-analysis by Guillaume Villatte (5675465)

“…<div><p>Introduction</p><p>Total Shoulder Arthroplasty (TSA) anatomical, reverse or both is an increasingly popular procedure but the glenoid component is still a weak element, accounting for 30–50% of mechanical complications and contributing to the revision burden. …”

Demonstration of a Direct Interaction between β₂-Adrenergic Receptor and Insulin Receptor by BRET and Bioinformatics by Maja Mandić (662591)

“…Calculated acceptor/donor (AD₅₀) values as a measure of the relative affinity for homo- and heteromer formation differed among the heteromers that could not be explained by a simple dimer model. …”

Image1_Enhancing decellularized vascular scaffolds with PVDF and PCL reinforcement: a fused deposition modeling approach.jpeg by Kirill Yu. Klyshnikov (11151429)

“…In contrast, both PVDF and PCL reinforced scaffolds did not exhibit significant property degradation, with deformations ranging 0.1–0.13 mm depending on the model, and a maximum decrease in the modulus of elasticity of 23%.…”

A Randomized, Controlled, Trial of Short Cycle Intermittent Compared to Continuous Antiretroviral Therapy for the Treatment of HIV Infection in Uganda by Steven J. Reynolds (247956)

“…</p><h3>Methods</h3><p>A 72 week, non-inferiority trial enrolled one hundred forty six HIV positive persons receiving ART (CD4+ cell count ≥125 cells/mm³ and HIV RNA plasma levels <50 copies/ml) in one of three arms: continuous, 7 days on/7 days off and 5 days on/2 days off treatment. …”

Data_Sheet_1_Influence of the First Wave of the COVID-19 Pandemic on Cancer Care in a German Comprehensive Cancer Center.docx by Johanna Kirchberg (11745386)

“…During the first shutdown, March–May 2020, the total number of presentations was 9.4% (−18.7, 1) less than during March–May 2019. This decrease was significant for curable cases of esophageal cancer [N = 37, 25.5% (−41.8, −4.4)] and colon cancer [N = 36, 17.5% (−32.6, 1.1)] as well as for all cases of biliary tract cancer [N = 26, 50% (−69.9, −15)] during the first shutdown from March 2020 to May 2020.…”

Supplementary Material for: Association between Preoperative Monocyte-to-Lymphocyte Ratio and Late Arteriovenous Fistula Dysfunction in Hemodialysis Patients: A Cohort Study by Hu S. (5689703)

“…Association of preoperative MLR with AVF dysfunction (thrombosis or decrease of normal vessel diameter by >50%, requiring either surgical revision or percutaneous transluminal angioplasty) was assessed by multivariable Cox proportional hazard regression. …”

Supplementary Material for: Understanding the growing burden of Malignant Pleural Effusion – epidemiology, health care utilization and cost, a Canadian perspective by Czarnecka-Kujawa K. (9038435)

“…Annual mortality among prevalent patients decreased from 32% to 28%. In 2004, 57% of patients were hospitalized, decreasing to 50% in 2018. …”

A simple stochastic step model explains Reactive Oxygen Species production in cell populations undergoing senescence and in immortal cells. by Conor Lawless (183686)

“…B) Normalised, mean MitoSOX fluorescence measured by flow cytometry varies with PD in MRC5 fibroblasts cultivated until senescence (blue points). …”

Data_Sheet_1_The micro and macro interactions in acute autoimmune encephalitis: a study of resting-state EEG.DOCX by Xin Luo (428648)

“…</p>Results<p>Compared with the HC group, significantly decreased FC across whole brain regions at alpha and beta bands were found in AIE patients. …”

[A] Histopathological images of pancreas, liver, kidney, and heart tissues from the studied rat groups, stained with H&E. by Mohamed Lotfy (18599184)

“…Pancreas: Untreated diabetic rats show a reduction in the size of pancreatic islets of Langerhans (IL), correlated with a decrease in insulin-secreting beta cells. …”

FIGURE 1 from Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer by Siddharth Mehra (15666660)

“…Scale bar = 50 μm. Individual datapoints with mean ± SEM are shown and compared by two-tailed unpaired <i>t</i> test for two group comparison and one-way ANOVA for multiple comparisons; *, <i>P</i> < 0.05; **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001; ^ns, <i>P</i> > 0.05.…”

Evolution of climate parameters in the AEZ2 from the 1990 to 2022 data series. by Jean M. Mondo (12883464)