Image_1_Thermoresponsive Copolymer Nanovectors Improve the Bioavailability of Retrograde Inhibitors in the Treatment of Leishmania Infections.tif by Evan Craig (4025492)

“…It is, therefore, imperative that more effective drug formulations with decreased toxicity profiles are developed. Previous studies had shown that 2-(((5-Methyl-2-thienyl)methylene)amino)-N-phenylbenzamide (also called Retro-2) has efficacy against Leishmania infections. …”

Data_Sheet_1_Differential Genome Size and Repetitive DNA Evolution in Diploid Species of Melampodium sect. Melampodium (Asteraceae).PDF by Jamie McCann (3111606)

“…The investigated genomes range in size from 0.49 to 2.27 pg/1C (ca. 4.5-fold variation), despite having the same base chromosome number (x = 10) and very strong phylogenetic affinities. …”

Image1_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopausal... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Data_Dheet_1_Endothelial Progenitor Cells Produced From Human Pluripotent Stem Cells by a Synergistic Combination of Cytokines, Small Compounds, and Serum-Free Medium.zip by Simon Farkas (8848784)

“…This differentiation process yields up to 15 differentiated cells per seeded hPSC in 5 days. Endothelial progenitor cells constitute up to 97% of these derived cells. …”

Image3_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…Maximum cyanobacteria richness was observed at approximately 27.5°C, declining at higher and lower temperatures (polynomial fit, R² = 0.2, p<0.0001). …”

Supplementary Material for: Characteristics and Outcomes of Endoscopies before and during the COVID-19 Pandemic in New York by Annadurai V. (10645559)

“…<b><i>Methods:</i></b> Across 3 hospitals, we compared demographics, indications, and yield of endoscopies before and after March 16, 2020, the date on which elective procedures were canceled, as well as a recovery period for 5 months after they were resumed. …”

Image_4_Identification of Immune-Related Genes MSR1 and TLR7 in Relation to Macrophage and Type-2 T-Helper Cells in Osteosarcoma Tumor Micro-Environments as Anti-metastasis Signatu... by Zhiyu Chen (669085)

“…Both internal and external data were verified. We found that macrophages and Type-2 T-helper cells were significantly decreased in patients with OS metastases. …”

Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…The effect of RNA2.7 on other forms of cell death is still unclear. In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Table_1_RNA 2’-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.docx by Panpan Li (484033)

“…Once FBL is down-regulated, the decreased Nm modifications of RNA in macrophages may act as “non-self” RNA and be recognized by RNA sensor interferon induced with helicase C domain 1 (MDA5), leading to innate immune activation by inducing the expression of IFN-I and ISGs. …”

Table 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.docx by Songtao Li (186776)

“…DASH scores had a negative association with the risk of OSA (OR = 0.91, 95%CI: 0.88–0.95, p < 0.01). Next, we divided DASH scores into quintiles groups. In comparison to the reference group Q1, groups Q5 had adjusted OR values of 0.63 (95%CI: 0.52–0.76, p < 0.01). …”

Data Sheet 1_Assessing the importance of acoustic backscatter and bottom trawling impact as predictor variables for mapping deep sea coral reefs.docx by Christopher Berry (6418166)

“…The reduction in extent of coral VME area was dependent on the probability threshold of habitat suitability used in the model, decreasing by 20.44%–26.07% following trawling across a range of thresholds from 0.5–0.85. …”

Presentation_2_Genome-Wide CRISPR/Cas9 Screen Identifies New Genes Critical for Defense Against Oxidant Stress in Toxoplasma gondii.pdf by Yun Chen (279569)

“…In addition, several previously uncharacterized genes were identified, among which five hypothetical protein-coding genes, namely, HP1–HP5, were selected for further functional characterization. …”

Physiology and effects of nucleosides in mice lacking all four adenosine receptors by Cuiying Xiao (78044)

“…However, the mice showed decreased survival starting at about 15 weeks of age. …”

Table_3_RNA 2’-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.docx by Panpan Li (484033)

“…Once FBL is down-regulated, the decreased Nm modifications of RNA in macrophages may act as “non-self” RNA and be recognized by RNA sensor interferon induced with helicase C domain 1 (MDA5), leading to innate immune activation by inducing the expression of IFN-I and ISGs. …”

Self-Healable, Recyclable, and Strengthened Epoxidized Natural Rubber/Carboxymethyl Chitosan Biobased Composites with Hydrogen Bonding Supramolecular Hybrid Networks by Chuanhui Xu (516106)

“…To solve this problem, in this paper, we constructed a hydrogen bonding supramolecular hybrid network by incorporating carboxymethyl chitosan (CMCS) into epoxidized natural rubber (ENR) through a solution-mixing method. …”

Table 1_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc by Yi Shan (160293)

“…</p>Results<p>The total all-age prevalence and DALYs due to IOFBs rose by 41.9 and 35.5%, respectively, from 1990 to 2021, and the age-standardized prevalence and DALYs rates decreased by 15.2 and 19.6%. …”

Image_7_Genome Analysis Coupled With Transcriptomics Reveals the Reduced Fitness of a Hot Spring Cyanobacterium Mastigocladus laminosus UU774 Under Exogenous Nitrogen Supplement.TI... by Mayuri Mukherjee (11009623)

“…Among genes showing extreme downregulation when grown in a medium supplemented with nitrogen with the fold change > 5 are transcriptional regulator gene WalR, carbonic anhydrases, RNA Polymerase Sigma F factor, fimbrial protein, and twitching mobility protein. …”

FA_<i>x</i>Cs_1–<i>x</i>PbI₃ Nanocrystals: Tuning Crystal Symmetry by A‑Site Cation Composition by Julian A. Vigil (1768927)

“…All compositions crystallize in the perovskite structure; however, the average structure lowers in symmetry from the α (cubic) to β (tetragonal) to γ (orthorhombic) perovskite phases with decreasing <i>x</i> (Cs addition). The corresponding α- to β- and β- to γ-phase transitions occur between <i>x</i> = 0.75–0.5 and <i>x</i> = 0.25–0.1, respectively. …”

Cs₄CuSb₂Cl₁₂ Nanostructured Layered Films for Humidity and Temperature Sensing Applications by Julfikar Ali Sarkar (22088806)

DataSheet_1_Will previous antimicrobial therapy reduce the positivity rate of metagenomic next-generation sequencing in periprosthetic joint infections? A clinical study.pdf by Linjie Hao (13866158)

“…</p>Results<p>Among 131 included PJIs, 91 (69.5%) had positive cultures and 115 (87.8%) had positive mNGS results. …”